(Q81320653)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18496560%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16 (English)

1 reference

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7 January 2020

3

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7 January 2020

author name string

U Modlich

1

1 reference

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7 January 2020

A Schambach

2

1 reference

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7 January 2020

D C Wicke

4

1 reference

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7 January 2020

S Knoess

5

1 reference

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7 January 2020

Z Li

6

1 reference

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7 January 2020

T Maetzig

7

1 reference

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7 January 2020

C Rudolph

8

1 reference

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7 January 2020

B Schlegelberger

9

1 reference

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7 January 2020

C Baum

10

1 reference

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7 January 2020

publication date

22 May 2008

1 reference

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7 January 2020

1 reference

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7 January 2020

volume

22

1 reference

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7 January 2020

issue

8

1 reference

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7 January 2020

page(s)

1519-1528

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https://scigraph.springernature.com/pub.10.1038/leu.2008.118

7 January 2020

exact match

0 references

cites work

Efficacy of gene therapy for SCID is being confirmed

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7 January 2021

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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7 January 2021

Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning

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7 January 2021

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

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7 January 2021

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

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7 January 2021

Murine leukemia induced by retroviral gene marking

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7 January 2021

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque

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7 January 2021

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

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7 January 2021

Gene therapy for severe combined immunodeficiency: are we there yet?

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7 January 2021

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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7 January 2021

Case of leukaemia associated with X-linked severe combined immunodeficiency gene therapy trial in London

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7 January 2021

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Physiological promoters reduce the genotoxic risk of integrating gene vectors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Gene therapy: therapeutic gene causing lymphoma

1 reference

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7 January 2021

Gene therapy: X-SCID transgene leukaemogenicity

1 reference

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7 January 2021

Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.

1 reference

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7 January 2021

Gene therapy: is IL2RG oncogenic in T-cell development?

1 reference

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7 January 2021

Design of 5' untranslated sequences in retroviral vectors developed for medical use.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Context Dependence of Different Modules for Posttranscriptional Enhancement of Gene Expression from Retroviral Vectors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

A third-generation lentivirus vector with a conditional packaging system

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Retroviral transduction of human CD34+ cells on fibronectin fragment CH-296 is inhibited by high concentrations of vector containing medium

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Cancer biology: summing up cancer stem cells.

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7 January 2021

New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy

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https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

RTCGD: retroviral tagged cancer gene database

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https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Hot spots of retroviral integration in human CD34+ hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

EVI1 and hematopoietic disorders: history and perspectives

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

EVI1 induces myelodysplastic syndrome in mice

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Erythroid defects and increased retrovirally-induced tumor formation in Evi1 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Breakpoints at 1p36.3 in three MDS/AML(M4) patients with t(1;3)(p36;q21) occur in the first intron and in the 5' region of MEL1.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

MEL1S, not MEL1, is overexpressed in myelodysplastic syndromes patients with t(1;3)(p36;q21)

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Overexpression of PRDM16 in the presence and absence of the RUNX1/PRDM16 fusion gene in myeloid leukemias.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functions

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Leukemogenesis of the EVI1/MEL1 gene family

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021

Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.118

7 January 2021