(Q81455974)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

Reporter mice and drug discovery and development (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Paolo Ciana

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

publication date

1 March 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

4

1 reference

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9 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

249-255

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

A brief history of novel drug discovery technologies

9 January 2020

cites work

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Knockouts model the 100 best-selling drugs--will they model the next 100?

31 March 2020

1 reference

A guide to drug discovery: Target selection in drug discovery

31 March 2020

1 reference

Ligand-inducible and liver-specific target gene expression in transgenic mice

31 March 2020

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Retinoid-X receptor signalling in the developing spinal cord

31 March 2020

1 reference

Feedback-inducible nuclear-receptor-driven reporter gene expression in transgenic mice

31 March 2020

1 reference

Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs), and Xenobiotics.

31 March 2020

1 reference

Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis

31 March 2020

1 reference

Analysis of perinatal gene expression: hormone response elements mediate activation of a lacZ reporter gene in liver of transgenic mice

31 March 2020

1 reference

In vivo imaging of transcriptionally active estrogen receptors.

31 March 2020

1 reference

Tumor induction of VEGF promoter activity in stromal cells

31 March 2020

1 reference

Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice

31 March 2020

1 reference

In vivo imaging of NF-kappa B activity

31 March 2020

1 reference

Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid

31 March 2020

1 reference

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

31 March 2020

1 reference

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

31 March 2020

1 reference

The price of innovation: new estimates of drug development costs

31 March 2020

1 reference

Science, pharmacoeconomics and ethics in drug R&D: a sustainable future scenario?

31 March 2020

1 reference

Cutting the cost of drug development?

31 March 2020

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Pharmaceutical use of mouse models humanized for the xenobiotic receptor

31 March 2020

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Predicting therapeutic value in the lead optimization phase of drug discovery

31 March 2020

1 reference

The molecular properties and applications of Anthozoa fluorescent proteins and chromoproteins.

31 March 2020

1 reference

Kindling fluorescent proteins for precise in vivo photolabeling

31 March 2020

1 reference

Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies

31 March 2020

1 reference

Fluorescence-based assays for RGS box function

31 March 2020

1 reference

Noninvasive quantitative imaging of protein-protein interactions in living subjects

31 March 2020

1 reference

Molecular imaging in living subjects: seeing fundamental biological processes in a new light

31 March 2020

1 reference

Advances in in vivo bioluminescence imaging of gene expression

31 March 2020

1 reference

Technicolour transgenics: imaging tools for functional genomics in the mouse

31 March 2020

1 reference

In vivo visualization of gene expression using magnetic resonance imaging

31 March 2020

1 reference

Human transferrin receptor gene as a marker gene for MR imaging

31 March 2020

1 reference

Noninvasive imaging of reporter gene expression in living subjects

31 March 2020

1 reference

Molecular imaging in drug discovery and development

31 March 2020

1 reference

Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD1661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15738979%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference