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English
PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication
scientific article published on 18 December 2005
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
title
PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author
Johannes C Walter
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
Emily E Arias
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
publication date
18 December 2005
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
8
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
page(s)
84-90
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/ncb1346
0 references
cites work
Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferating cell nuclear antigen (PCNA): a dancer with many partners
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of DNA replication in eukaryotic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of DNA replication in Xenopus egg extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic DNA Polymerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of peptides from p21 (Waf1/Cip1) to investigate PCNA function in Xenopus egg extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function and regulation of cullin-RING ubiquitin ligases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualization of replication initiation and elongation in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two modes of FEN1 binding to PCNA regulated by DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein associations in DnaA-ATP hydrolysis mediated by the Hda-replicase clamp complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated chromosomal DNA replication in the absence of a nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCB1346
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
Dimensions Publication ID
1043088176
0 references
PubMed ID
16362051
1 reference
stated in
Europe PubMed Central
PubMed ID
16362051
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362051%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
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