(Q81944524)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Role of protein flexibility in the design of Bcl-X(L) targeting agents: insight from molecular dynamics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

author name string

William Novak

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Hongming Wang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Goran Krilov

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

publication date

9 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

Journal of Computer - Aided Molecular Design

13 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

page(s)

49-61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10822-008-9237-0

13 January 2020

exact match

0 references

cites work

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

1 reference

12 December 2020

The role of the Bcl-2 protein family in cancer

1 reference

12 December 2020

Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL

1 reference

12 December 2020

Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.

1 reference

12 December 2020

Design, synthesis, and computational studies of inhibitors of Bcl-XL.

1 reference

12 December 2020

Canonical dynamics: Equilibrium phase-space distributions

1 reference

12 December 2020

Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo

1 reference

12 December 2020

Molecular dynamics study of peptide segments of the BH3 domain of the proapoptotic proteins Bak, Bax, Bid and Hrk bound to the Bcl-xL and Bcl-2 proteins.

1 reference

12 December 2020

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

1 reference

12 December 2020

Strategies for targeting protein-protein interactions with synthetic agents.

1 reference

12 December 2020

Modulation of protein-protein interactions with small organic molecules

1 reference

12 December 2020

Structural biology of the Bcl-2 family of proteins

1 reference

12 December 2020

A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors

1 reference

12 December 2020

Transient Pockets on Protein Surfaces Involved in Protein−Protein Interaction

1 reference

12 December 2020

An informatics approach identifying markers of chemosensitivity in human cancer cell lines.

1 reference

12 December 2020

The role of Bcl-2 family members in tumorigenesis

1 reference

12 December 2020

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

12 December 2020

Construction of a three-dimensional pharmacophore for Bcl-2 inhibitors by flexible docking and the multiple copy simultaneous search method.

1 reference

12 December 2020

GROMACS: fast, flexible, and free

1 reference

12 December 2020

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

12 December 2020

Discovering high-affinity ligands for proteins: SAR by NMR

1 reference

12 December 2020

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis

1 reference

12 December 2020

Bcl-XL Mutations Suppress Cellular Sensitivity to Antimycin A

1 reference

12 December 2020

Molecular dynamics simulation and automated docking of the pro-apoptotic Bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70

1 reference

12 December 2020

A matter of life and death

1 reference

12 December 2020

Protein-protein interactions: lessons learned

1 reference

12 December 2020

How the Bcl-2 family of proteins interact to regulate apoptosis.

1 reference

12 December 2020

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

12 December 2020

pi-Stacking interactions. Alive and well in proteins

1 reference

12 December 2020

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

12 December 2020

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

1 reference

12 December 2020

10.1007/S10822-008-9237-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780145%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

DBLP publication ID

journals/jcamd/NovakWK09

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference