(Q82705613)

English

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

scientific article published on 01 February 2011

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17 January 2020

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways (English)

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17 January 2020

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Roser Gorina

1

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17 January 2020

Miriam Font-Nieves

2

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17 January 2020

Leonardo Márquez-Kisinousky

3

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17 January 2020

Tomàs Santalucia

4

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17 January 2020

Anna M Planas

5

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17 January 2020

publication date

1 February 2011

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17 January 2020

1 reference

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17 January 2020

59

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17 January 2020

2

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17 January 2020

242-255

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17 January 2020

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The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)

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Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association

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Immune function of astrocytes

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IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking

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Mig and IP-10: CXC chemokines that target lymphocytes

1 reference

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7 January 2021

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Astrocytes are active players in cerebral innate immunity

1 reference

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7 January 2021

based on heuristic

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

1 reference

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Egr-1 target genes in human endothelial cells identified by microarray analysis

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Blockade of IL-15 activity inhibits microglial activation through the NFkappaB, p38, and ERK1/2 pathways, reducing cytokine and chemokine release

1 reference

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7 January 2021

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Astrocyte control of the cerebrovasculature.

1 reference

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7 January 2021

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Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490

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Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA.

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7 January 2021

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LPS induction of gene expression in human monocytes

1 reference

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7 January 2021

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Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway

1 reference

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7 January 2021

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STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

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7 January 2021

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Neurological autoimmunity targeting aquaporin-4.

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7 January 2021

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Triggering the interferon response: the role of IRF-3 transcription factor

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7 January 2021

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Endotoxin-induced maturation of MyD88-deficient dendritic cells

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7 January 2021

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Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21094

7 January 2021

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Signaling to NF-kappaB by Toll-like receptors

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7 January 2021

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Early growth response-1 in cardiovascular pathobiology

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7 January 2021

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TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.21094

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Kinetics of inflammatory response of astrocytes induced by TLR 3 and TLR4 ligation

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Suppressors of cytokine signalling: SOCS.

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Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Toll-like Receptors in Multiple Sclerosis Mouse Experimental Models

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Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

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Differential roles of ICAM-1 and VCAM-1 in leukocyte-endothelial cell interactions in skin and brain of MRL/faslpr mice

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1 reference

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Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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1 reference

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Chemokines and matrix metalloproteinase-9 in leukocyte recruitment to the central nervous system.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

10.1002/GLIA.21094

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21125645%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21125645%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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