(Q37003216)

English

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

scientific article published on 29 May 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

apoptotic process

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toll-like receptor

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10

object named as

Mark P Mattson

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Justin D Lathia

2

object named as

Justin D Lathia

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

William R. Markesbery

8

object named as

William R Markesbery

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Sung-Chun Tang

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Pradeep K Selvaraj

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Dong-Gyu Jo

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Mohamed R Mughal

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Aiwu Cheng

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Dominic A Siler

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Thiruma V Arumugam

9

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17 August 2017

language of work or name

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publication date

29 May 2008

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Europe PubMed Central

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17 August 2017

Experimental Neurology

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Europe PubMed Central

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17 August 2017

213

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Europe PubMed Central

PMC publication ID

17 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

114-121

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

Toll-like receptor signal transduction

1 reference

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29 September 2017

Toll-like receptors modulate adult hippocampal neurogenesis

1 reference

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29 September 2017

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

1 reference

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29 September 2017

Viral recognition by Toll-like receptors

1 reference

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29 September 2017

Cooperation of Toll-like receptor signals in innate immune defence

1 reference

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29 September 2017

TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage

1 reference

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29 September 2017

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).

1 reference

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29 September 2017

TLR signaling pathways: opportunities for activation and blockade in pursuit of therapy

1 reference

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29 September 2017

The innate immune facet of brain: human neurons express TLR-3 and sense viral dsRNA.

1 reference

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29 September 2017

Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

1 reference

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29 September 2017

Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage.

1 reference

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29 September 2017

Role of toll-like receptor signalling in Abeta uptake and clearance

1 reference

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29 September 2017

Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

1 reference

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29 September 2017

Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.

1 reference

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29 September 2017

Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta.

1 reference

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29 September 2017

Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

The Toll-like receptors: analysis by forward genetic methods

1 reference

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29 September 2017

Glia and their cytokines in progression of neurodegeneration

1 reference

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29 September 2017

The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia

1 reference

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29 September 2017

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

1 reference

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29 September 2017

Pathways towards and away from Alzheimer's disease

1 reference

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29 September 2017

Endogenous ligands of Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

1 reference

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29 September 2017

Yin and Yang: complement activation and regulation in Alzheimer’s disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

29 September 2017

Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide

1 reference

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29 September 2017

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

1 reference

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29 September 2017

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

1 reference

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29 September 2017

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

1 reference

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29 September 2017

Complement anaphylatoxin receptors on neurons: new tricks for old receptors?

1 reference

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29 September 2017

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

1 reference

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29 September 2017

Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4.

1 reference

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29 September 2017

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

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29 September 2017

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

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29 September 2017

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

1 reference

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27 June 2018

Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

Glycosaminoglycans in cortical autopsy samples from Alzheimer brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

27 June 2018

Hyaluronan expression following middle cerebral artery occlusion in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Changes in hyaluronan production and metabolism following ischaemic stroke in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Complement activation in very early Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 September 2018

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

20 October 2018

Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597513

4 December 2018

beta-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal pattern of C1q deposition after transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18586243

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPNEUROL.2008.05.014

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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