(Q83975861)

English

Inhibition of nuclear factor erythroid 2-related factor 2 exacerbates HIV-1 gp120-induced oxidative and inflammatory response: role in HIV associated neurocognitive disorder

scientific article published on 25 April 2012

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scholarly article

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Europe PubMed Central

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29 January 2020

Inhibition of nuclear factor erythroid 2-related factor 2 exacerbates HIV-1 gp120-induced oxidative and inflammatory response: role in HIV associated neurocognitive disorder (English)

1 reference

Europe PubMed Central

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29 January 2020

3

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29 January 2020

author name string

Pichili Vijaya Bhaskar Reddy

1

1 reference

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29 January 2020

Marisela Agudelo

2

1 reference

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29 January 2020

Madhavan P Nair

4

1 reference

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29 January 2020

publication date

25 April 2012

1 reference

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29 January 2020

Neurochemical Research

1 reference

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29 January 2020

37

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29 January 2020

8

1 reference

Europe PubMed Central

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29 January 2020

1697-1706

1 reference

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29 January 2020

https://scigraph.springernature.com/pub.10.1007/s11064-012-0779-0

0 references

Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive neuropsychology of HIV-associated neurocognitive disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the blood-brain barrier disruption in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of sulforaphane against oxidative stress: recent advances

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2-Keap1 defines a physiologically important stress response mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death in HIV dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What is oxidative stress?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH oxidase drives cytokine and neurotoxin release from microglia and macrophages in response to HIV-Tat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between neurological progression and astrocyte apoptosis in HIV-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 is involved in inhibiting Tat-induced HIV-1 long terminal repeat transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure to gp120 of HIV‐1 Induces an Increased Release of Arachidonic Acid in Rat Primary Neuronal Cell Culture Followed by NMDA Receptor‐mediated Neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species generated by glia are responsible for neuron death induced by human immunodeficiency virus-glycoprotein 120 in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-associated neurocognitive disorders: is there a hidden epidemic?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel markers of oxidative stress in actively progressive HIV dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants, oxidative damage and oxygen deprivation stress: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinflammatory cytokines and HIV-1 synergistically enhance CXCL10 expression in human astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nox2-based NADPH oxidase mediates HIV-1 Tat-induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of matrix metalloproteinase-9 activity in the cerebrospinal fluid of human immunodeficiency virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Nrf2 enhances the upregulation of nuclear factor-kappaB activity, tumor necrosis factor-α, and matrix metalloproteinase-9 after spinal cord injury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and modulation of an NADPH oxidase in mammalian astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Models of neuronal injury in AIDS: another role for the NMDA receptor?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage induced by the injection of HIV-1 Tat protein in the rat striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat activates dual Nox pathways leading to independent activation of ERK and JNK MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helicobacter pylori induces matrix metalloproteinase-9 through activation of nuclear factor kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular HIV-1 Tat up-regulates expression of matrix metalloproteinase-9 via a MAPK-NF-kappaB dependent pathway in human astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of HIV-1 proteins gp120 and Tat in the rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV and antiretroviral therapy in the brain: neuronal injury and repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal relationships between HIV-1 Tat-induced neuronal degeneration, OX-42 immunoreactivity, reactive astrocytosis, and protein oxidation in the rat striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gp120 modulates hypothalamic cytokine mRNAs in vivo: implications to cytokine feedback systems.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: role in HIV associated neurocognitive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The aging of human-immunodeficiency-virus-associated neurocognitive disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22528837

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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