(Q84393677)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706160%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706160%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Long Zhang

1

1 reference

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5 February 2020

FangFang Zhou

2

1 reference

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5 February 2020

Yvette Drabsch

3

1 reference

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5 February 2020

Rui Gao

4

1 reference

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5 February 2020

B Ewa Snaar-Jagalska

5

1 reference

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5 February 2020

Craig Mickanin

6

1 reference

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5 February 2020

Huizhe Huang

7

1 reference

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5 February 2020

Kelly-Ann Sheppard

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706160%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Jeff A Porter

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706160%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Chris X Lu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22706160%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Peter ten Dijke

11

1 reference

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5 February 2020

publication date

17 June 2012

1 reference

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5 February 2020

1 reference

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5 February 2020

volume

14

1 reference

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5 February 2020

page(s)

717-726

1 reference

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5 February 2020

issue

7

1 reference

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https://scigraph.springernature.com/pub.10.1038/ncb2522

5 February 2020

exact match

0 references

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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

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UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself

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Non-Smad pathways in TGF-beta signaling

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12 December 2020

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

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12 December 2020

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis

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12 December 2020

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

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12 December 2020

Key role for ubiquitin protein modification in TGFβ signal transduction

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12 December 2020

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

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12 December 2020

Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration.

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12 December 2020

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.

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12 December 2020

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

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12 December 2020

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

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12 December 2020

Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors

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12 December 2020

AKT/PKB signaling: navigating downstream

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12 December 2020

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

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12 December 2020

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

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The regulation of TGFbeta signal transduction

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USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

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USP15 is a deubiquitylating enzyme for receptor-activated SMADs

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A genomic and functional inventory of deubiquitinating enzymes

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12 December 2020

USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation

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A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition

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TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

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12 December 2020

Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

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12 December 2020

Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

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12 December 2020

Regulating the stability of TGFbeta receptors and Smads

1 reference

12 December 2020