(Q85167441)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Activated Sterol Regulatory Element-Binding Protein-2 Suppresses Hepatocyte Nuclear Factor-4-Mediated Cyp3a11 Expression in Mouse Liver (English)

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

enzymologic gene expression regulation

28 July 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20926756

cytochrome P-450 CYP3A inhibitors

28 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20926756

28 July 2024

2

Kouichi Yoshinari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20926756

28 July 2024

author name string

Shin-ichi Inoue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Mika Sugawara

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Yasushi Yamazoe

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20926756

28 July 2024

publication date

6 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

15 February 2020

http://molpharm.aspetjournals.org/cgi/content/abstract/79/1/148

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20926756

https://syndication.highwire.org/content/doi/10.1124/mol.110.068577

28 July 2024

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

28 July 2024

published in

Molecular Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

148-156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver

15 February 2020

cites work

1

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.

28 July 2024

2

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Metabolism of 4 beta -hydroxycholesterol in humans.

28 July 2024

3

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.

28 July 2024

4

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

28 July 2024

5

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

CYP3A genetics in drug metabolism

28 July 2024

6

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Human cytochromes P450: problems and prospects

28 July 2024

7

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription

28 July 2024

8

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

28 July 2024

9

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis.

28 July 2024

10

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Exclusive Homodimerization of the Orphan Receptor Hepatocyte Nuclear Factor 4 Defines a New Subclass of Nuclear Receptors

28 July 2024

12

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

28 July 2024

13

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA

28 July 2024

14

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.

28 July 2024

15

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver.

28 July 2024

16

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha

28 July 2024

17

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Transcriptional elements directing a liver-specific expression of P450/6 beta A (CYP3A2) gene-encoding testosterone 6 beta-hydroxylase

28 July 2024

18

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

28 July 2024

19

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Cytochrome P450s and cholesterol homeostasis

28 July 2024

20

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c

28 July 2024

21

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Activation of PPARgamma coactivator-1 through transcription factor docking

28 July 2024

22

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

28 July 2024

23

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state

28 July 2024

24

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Catalytic characteristics of CYP3A4: requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O-demethylated methoxychlor

28 July 2024

25

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics

28 July 2024

26

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

28 July 2024

27

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

28 July 2024

28

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4alpha-deficient mice

28 July 2024

29

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

28 July 2024

30

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

28 July 2024

31

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet

28 July 2024

32

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5'-flanking region

28 July 2024

33

1 reference

https://api.crossref.org/works/10.1124/MOL.110.068577

28 July 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926756%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference