(Q85277884)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25203160%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Activation of G-protein-coupled receptors correlates with the formation of a continuous internal water pathway (English)

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16 February 2020

1

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16 February 2020

Slawomir Filipek

series ordinal

2

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16 February 2020

3

Krzysztof Palczewski

1 reference

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16 February 2020

author name string

Horst Vogel

series ordinal

4

1 reference

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16 February 2020

publication date

9 September 2014

1 reference

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16 February 2020

published in

Nature Communications

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16 February 2020

volume

5

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16 February 2020

page(s)

4733

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https://scigraph.springernature.com/pub.10.1038/ncomms5733

16 February 2020

exact match

0 references

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Molecular signatures of G-protein-coupled receptors

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Role of bulk water in hydrolysis of the rhodopsin chromophore

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Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

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Crystal structure of metarhodopsin II

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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

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The role of water and sodium ions in the activation of the μ-opioid receptor

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Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling

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7 January 2021

Mechanism of signal propagation upon retinal isomerization: insights from molecular dynamics simulations of rhodopsin restrained by normal modes

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7 January 2021

The signaling pathway of rhodopsin

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Molecular control of δ-opioid receptor signalling

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

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7 January 2021

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

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7 January 2021

The structural basis of agonist-induced activation in constitutively active rhodopsin

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7 January 2021

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

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7 January 2021

Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

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7 January 2021

Structural Features for Functional Selectivity at Serotonin Receptors

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7 January 2021

The dynamic process of β(2)-adrenergic receptor activation

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7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

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7 January 2021

Ligand-dependent activation and deactivation of the human adenosine A(2A) receptor.

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7 January 2021

Action of molecular switches in GPCRs--theoretical and experimental studies.

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7 January 2021

Arrestin specificity for G protein-coupled receptors in human airway smooth muscle

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7 January 2021

Activation mechanism of the β2-adrenergic receptor

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7 January 2021

Structural Basis for Molecular Recognition at Serotonin Receptors

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7 January 2021

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

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7 January 2021

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

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7 January 2021

Opsin, a structural model for olfactory receptors?

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7 January 2021

The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations

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7 January 2021

Lipid receptor S1P₁ activation scheme concluded from microsecond all-atom molecular dynamics simulations

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7 January 2021

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling

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7 January 2021

Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKa Values.

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7 January 2021

Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: decrease in activity after chronic morphine treatment

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7 January 2021

In vitro autoradiographic localization of 5-HT1A receptor-activated G-proteins in the rat brain

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7 January 2021

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7 January 2021

Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution.

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7 January 2021

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7 January 2021

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

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7 January 2021

g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbation

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7 January 2021

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7 January 2021

Anisotropic solvent model of the lipid bilayer. 1. Parameterization of long-range electrostatics and first solvation shell effects

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7 January 2021

Anisotropic solvent model of the lipid bilayer. 2. Energetics of insertion of small molecules, peptides, and proteins in membranes

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7 January 2021

Improved side-chain torsion potentials for the Amber ff99SB protein force field

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7 January 2021

Derivation and systematic validation of a refined all-atom force field for phosphatidylcholine lipids

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7 January 2021

An Extension and Further Validation of an All-Atomistic Force Field for Biological Membranes.

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7 January 2021

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7 January 2021

Time-resolved WAXS reveals accelerated conformational changes in iodoretinal-substituted proteorhodopsin

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7 January 2021

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7 January 2021

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7 January 2021

Well-Tempered Metadynamics: A Smoothly Converging and Tunable Free-Energy Method

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7 January 2021

Mechanism of membrane curvature sensing by amphipathic helix containing proteins

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7 January 2021

Reconstructing the equilibrium Boltzmann distribution from well-tempered metadynamics.

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7 January 2021

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7 January 2021

Features and development of Coot

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7 January 2021

Identifiers

DOI

10.1038/NCOMMS5733

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25203160%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 February 2020

ADS bibcode

2014NatCo...5.4733Y

0 references

1023610465

0 references

1 reference