(Q89631276)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

review article

1 reference

title

Fibroblasts in the Tumor Microenvironment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

author name string

Marta Truffi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

Luca Sorrentino

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

Fabio Corsi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

publication date

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

Advances in Experimental Medicine and Biology

7 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

volume

1234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

page(s)

15-29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.

7 April 2020

cites work

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Fibroblasts in the Tumor Microenvironment: Shield or Spear?

31 March 2020

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Overexpression of TGF-beta by infiltrated granulocytes correlates with the expression of collagen mRNA in pancreatic cancer

31 March 2020

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The tumor microenvironment at a glance.

31 March 2020

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T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets

31 March 2020

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Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

31 March 2020

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Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer.

31 March 2020

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PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

31 March 2020

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Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy

31 March 2020

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Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines

31 March 2020

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Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15.

31 March 2020

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Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

31 March 2020

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Stromal gene expression defines poor-prognosis subtypes in colorectal cancer.

31 March 2020

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

31 March 2020

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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

31 March 2020

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Turning foes to friends: targeting cancer-associated fibroblasts

31 March 2020

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A tenascin C targeted nanoliposome with navitoclax for specifically eradicating of cancer-associated fibroblasts.

31 March 2020

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Remodeling the Tumor Microenvironment with Emerging Nanotherapeutics.

31 March 2020

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Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer.

31 March 2020

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Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling

31 March 2020

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GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment

31 March 2020

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HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis

31 March 2020

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Understanding fibroblast heterogeneity in the skin

31 March 2020

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Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics

31 March 2020

1 reference

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Alteration of the tumor stroma using a consensus DNA vaccine targeting Fibroblast Activation Protein (FAP) synergizes with anti-tumor vaccine therapy in mice

31 March 2020

1 reference

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Fibroblasts from patients with breast cancer show abnormal migratory behaviour in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

31 March 2020

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Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer.

31 March 2020

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Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma

31 March 2020

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New functions for the matrix metalloproteinases in cancer progression

31 March 2020

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Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation

31 March 2020

1 reference

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Stromal gene expression predicts clinical outcome in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Focal Irradiation And Systemic Transforming Growth Factor β Blockade in Metastatic Breast Cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.

31 March 2020

1 reference

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Regulation of the anti-tumour immune response by cancer-associated fibroblasts

31 March 2020

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Gold Nanoparticle Transforms Activated Cancer-Associated Fibroblasts to Quiescence

31 March 2020

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Regulation of in situ to invasive breast carcinoma transition

31 March 2020

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Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.

31 March 2020

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Tumor microenvironment: Sanctuary of the devil.

31 March 2020

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Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment

31 March 2020

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Basement membranes: structure, assembly and role in tumour angiogenesis

31 March 2020

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The biology and function of fibroblasts in cancer

31 March 2020

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31 March 2020

Fibroblasts in cancer

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Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy

31 March 2020

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Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition.

31 March 2020

1 reference

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The role of myofibroblasts in upregulation of S100A8 and S100A9 and the differentiation of myeloid cells in the colorectal cancer microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Cancer-associated fibroblasts induce antigen-specific deletion of CD8 + T Cells to protect tumour cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Molecular mechanisms of epithelial-mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Origin and function of myofibroblasts in kidney fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Growth regulatory peptide production by human breast carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Fibroblast heterogeneity: implications for human disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Fibroblasts as architects of cancer pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

TGFβ signalling in context

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Using Gold Nanoparticles To Disrupt the Tumor Microenvironment: An Emerging Therapeutic Strategy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

The dynamic roles of TGF-β in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Phase I study of the angiogenesis inhibitor BIBF 1120 in patients with advanced solid tumors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Friends or foes - bipolar effects of the tumour stroma in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Phase II trial of single agent Val-boroPro (Talabostat) inhibiting Fibroblast Activation Protein in patients with metastatic colorectal cancer.

31 March 2020

1 reference

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Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Matrix metalloproteinases: biologic activity and clinical implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

In search of definitions: Cancer-associated fibroblasts and their markers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine

31 March 2020

1 reference

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

31 March 2020

1 reference

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Prognostic relevance of cancer-associated fibroblasts in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

PDGF receptors in tumor biology: prognostic and predictive potential

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Nintedanib plus docetaxel as second-line therapy in patients with non-small-cell lung cancer: a network meta-analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Fusion of Dendritic Cells and Cancer-Associated Fibroblasts for Activation of Anti-Tumor Cytotoxic T Lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Microenvironmental regulation of tumor progression and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Classification and biology of tumour associated stromal cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

A phase II double-blind study to investigate efficacy and safety of two doses of the triple angiokinase inhibitor BIBF 1120 in patients with relapsed advanced non-small-cell lung cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

The fibroblast: sentinel cell and local immune modulator in tumor tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Tumor cell interactions with the extracellular matrix during invasion and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Identification and characterization of a fibroblast marker: FSP1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Identification of fibroblast heterogeneity in the tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Myofibroblasts and mechano-regulation of connective tissue remodelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Crosstalk between fibroblasts and inflammatory cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Antibody targeting in metastatic colon cancer: a phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Improvement of anti-tumor immunity of fibroblast activation protein α based vaccines by combination with cyclophosphamide in a murine model of breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Vascular mimicry formation is promoted by paracrine TGF-β and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Targeting tumor architecture to favor drug penetration: a new weapon to combat chemoresistance in pancreatic cancer?

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

The role of promoter hypermethylation in fibroblast activation and fibrogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Gold Nanoparticles Disrupt Tumor Microenvironment - Endothelial Cell Cross Talk To Inhibit Angiogenic Phenotypes in Vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

Protein Nanocage Mediated Fibroblast-Activation Protein Targeted Photoimmunotherapy To Enhance Cytotoxic T Cell Infiltration and Tumor Control.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-030-37184-5_2

10.1007/978-3-030-37184-5_2

31 March 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32040852%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference