(Q90042455)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30505656%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

title

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives (English)

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10 April 2020

6

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10 April 2020

author name string

Gantumur Battogtokh

1

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10 April 2020

Yeon Su Choi

2

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10 April 2020

Dong Seop Kang

3

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10 April 2020

Sang Jun Park

4

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10 April 2020

Min Suk Shim

5

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10 April 2020

Yong-Yeon Cho

7

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10 April 2020

Joo Young Lee

8

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10 April 2020

Hye Suk Lee

9

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10 April 2020

Han Chang Kang

10

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10 April 2020

publication date

18 May 2018

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Acta Pharmaceutica Sinica B

10 April 2020

published in

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10 April 2020

volume

8

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10 April 2020

issue

6

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10 April 2020

page(s)

862-880

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Hydroquinone Dehydrogenases

10 April 2020

cites work

1 reference

12 December 2020

Differential retention of rhodamine 123 by breast carcinoma and normal human mammary tissue

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12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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12 December 2020

Study of the selective cytotoxic properties of cationic, lipophilic mitochondrial-specific compounds in gynecologic malignancies.

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12 December 2020

Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation

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12 December 2020

Selective killing of carcinoma cells "in vitro" by lipophilic-cationic compounds: a cellular basis

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12 December 2020

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

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12 December 2020

Mitochondria: a historical review

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12 December 2020

Synthesis and characterization of thiobutyltriphenylphosphonium bromide, a novel thiol reagent targeted to the mitochondrial matrix

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12 December 2020

Selective targeting of bioactive compounds to mitochondria

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12 December 2020

Photodynamic tumor therapy: mitochondrial benzodiazepine receptors as a therapeutic target.

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12 December 2020

DQAsomes: a novel potential drug and gene delivery system made from Dequalinium

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12 December 2020

Quantitative analysis of Pc 4 localization in mouse lymphoma (LY-R) cells via double-label confocal fluorescence microscopy

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12 December 2020

Mitochondrion as a novel target of anticancer chemotherapy

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12 December 2020

Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

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12 December 2020

Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells

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12 December 2020

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.

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12 December 2020

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

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12 December 2020

Delivery of bioactive molecules to mitochondria in vivo.

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12 December 2020

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

1 reference

12 December 2020

The fine structure of mitochondria

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12 December 2020

Studies on the enzymatic basis for the Janus green B staining reaction

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12 December 2020

THE ORGANIZATION OF LIVING MATTER

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12 December 2020

Rhodamine 123 as a probe of mitochondrial membrane potential: evaluation of proton flux through F(0) during ATP synthesis

1 reference

12 December 2020

The molecular machinery of Keilin's respiratory chain

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12 December 2020

Flavonoids: antioxidants or signalling molecules?

1 reference

12 December 2020

Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

1 reference

12 December 2020

Mitochondrial disorders

1 reference

12 December 2020

Mitochondrial dysfunction and type 2 diabetes

1 reference

12 December 2020

Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

1 reference

12 December 2020

Mitochondrial DNA mutations in human disease

1 reference

12 December 2020

Mitochondrial dysfunction in cancer

1 reference

12 December 2020

Reactive oxygen species: role in the development of cancer and various chronic conditions

1 reference

12 December 2020

Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario

1 reference

12 December 2020

Cell-permeable, mitochondrial-targeted, peptide antioxidants

1 reference

12 December 2020

Chlorinative stress: an under appreciated mediator of neurodegeneration?

1 reference

12 December 2020

Mitochondrial oxidative stress: implications for cell death

1 reference

12 December 2020

Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?

1 reference

12 December 2020

Mitochondrial dysfunction and molecular pathways of disease

1 reference

12 December 2020

Methods for the assessment of mitochondrial membrane permeabilization in apoptosis

1 reference

12 December 2020

Mitochondrial Aβ A potential cause of metabolic dysfunction in Alzheimer's disease

1 reference

12 December 2020

Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative

1 reference

12 December 2020

Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury

1 reference

12 December 2020

A biochemical approach to the problem of aging: "megaproject" on membrane-penetrating ions. The first results and prospects

1 reference

12 December 2020

Mitochondria targeting by guanidine- and biguanidine-porphyrin photosensitizers

1 reference

12 December 2020

Mitochondria in cancer cells: what is so special about them?

1 reference

12 December 2020

Mitochondria-penetrating peptides.

1 reference

12 December 2020

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis.

1 reference

12 December 2020

Opening and closing the metabolite gate

1 reference

12 December 2020

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.

1 reference

12 December 2020

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90

1 reference

12 December 2020

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

1 reference

12 December 2020

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

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12 December 2020

Targeting mitochondria with organelle-specific compounds: strategies and applications

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12 December 2020

Mitochondrial gateways to cancer

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12 December 2020

Mitochondrial dysfunction in Parkinson's disease

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12 December 2020

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.

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12 December 2020

A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator

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12 December 2020

Small mitochondria-targeting molecules as anti-cancer agents

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12 December 2020

Mitochondria-targeting properties and photodynamic activities of porphyrin derivatives bearing cationic pendant

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12 December 2020

Therapeutic targeting of mitochondrial superoxide in hypertension

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12 December 2020

Targeting mitochondria for cancer therapy

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12 December 2020

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

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12 December 2020

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

1 reference

12 December 2020

Quantitative proteomics discloses MET expression in mitochondria as a direct target of MET kinase inhibitor in cancer cells.

1 reference

12 December 2020

Approaches for targeting mitochondria in cancer therapy

1 reference

12 December 2020

Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis

1 reference

12 December 2020

Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

1 reference

12 December 2020

Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity

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12 December 2020

Identification and biological activities of a new antiangiogenic small molecule that suppresses mitochondrial reactive oxygen species

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12 December 2020

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

1 reference

12 December 2020

Derivatives of rhodamine 19 as mild mitochondria-targeted cationic uncouplers

1 reference

12 December 2020

Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells

1 reference

12 December 2020

Cell-permeable iminocoumarine-based fluorescent dyes for mitochondria

1 reference

12 December 2020

A highly selective, cell-permeable fluorescent nanoprobe for ratiometric detection and imaging of peroxynitrite in living cells

1 reference

12 December 2020

Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death

1 reference

12 December 2020

Targeting drugs to mitochondria

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12 December 2020

The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease.

1 reference

12 December 2020

A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic.

1 reference

12 December 2020

Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance

1 reference

12 December 2020

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

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12 December 2020

Targeting cancer cell mitochondria as a therapeutic approach

1 reference

12 December 2020

Folate conjugation to polymeric micelles via boronic acid ester to deliver platinum drugs to ovarian cancer cell lines

1 reference

12 December 2020

Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo

1 reference

12 December 2020

Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism

1 reference

12 December 2020

Targeted Delivery of Doxorubicin to Mitochondria

1 reference

12 December 2020

Antioxidants as therapies: can we improve on nature?

1 reference

12 December 2020

Membrane potential mediates the cellular binding of nanoparticles

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12 December 2020

Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death

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12 December 2020

Membrane potential and cancer progression

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12 December 2020

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines.

1 reference

12 December 2020

Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide

1 reference

12 December 2020

Evaluation of directly observed treatment short courses at a secondary health institution in Ibadan, Oyo State, Southwestern Nigeria

1 reference

12 December 2020

A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers

1 reference

12 December 2020

Targeting mitochondrial DNA with a platinum-based anticancer agent

1 reference

12 December 2020

Dual-targeting pro-apoptotic peptide for programmed cancer cell death via specific mitochondria damage

1 reference

12 December 2020

Mitochondrial form and function

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12 December 2020

Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis

1 reference

12 December 2020

Mitochondria-targeted spin traps: synthesis, superoxide spin trapping, and mitochondrial uptake

1 reference

12 December 2020

Peptide-chlorambucil conjugates combat pgp-dependent drug efflux

1 reference

12 December 2020

Nitric oxide donor doxorubicins accumulate into Doxorubicin-resistant human colon cancer cells inducing cytotoxicity

1 reference

12 December 2020

Design, synthesis and biological evaluation of mitochondria targeting theranostic agents

1 reference

12 December 2020

Mitochondria-targeted cancer therapy using a light-up probe with aggregation-induced-emission characteristics

1 reference

12 December 2020

Preventive and therapeutic effects of SkQ1-containing Visomitin eye drops against light-induced retinal degeneration.

1 reference

12 December 2020

Antihypertensive effect of mitochondria-targeted proxyl nitroxides

1 reference

12 December 2020

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

1 reference

12 December 2020

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism

1 reference

12 December 2020

Polyphenols as mitochondria-targeted anticancer drugs

1 reference

12 December 2020

Mitochondria-targeted antioxidants

1 reference

12 December 2020

Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity

1 reference

12 December 2020

A novel bifunctional mitochondria-targeted anticancer agent with high selectivity for cancer cells.

1 reference

12 December 2020

Tumor mitochondria-targeted photodynamic therapy with a translocator protein (TSPO)-specific photosensitizer

1 reference

12 December 2020

A mitochondria-targeted derivative of ascorbate: MitoC.

1 reference

12 December 2020

A mitochondria-targeted ratiometric fluorescent probe for rapid, sensitive and specific detection of biological SO2 derivatives in living cells.

1 reference

12 December 2020

Dual subcellular compartment delivery of doxorubicin to overcome drug resistant and enhance antitumor activity.

1 reference

12 December 2020

Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants

1 reference

12 December 2020

Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to Mitochondria.

1 reference

12 December 2020

Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ.

1 reference

12 December 2020

Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma

1 reference

12 December 2020

Mitochondrial-Targeting MET Kinase Inhibitor Kills Erlotinib-Resistant Lung Cancer Cells.

1 reference

12 December 2020

Mitochondrial-targeted photosensitizer-loaded folate-albumin nanoparticle for photodynamic therapy of cancer.

1 reference

12 December 2020

A fluorescent carbon-dots-based mitochondria-targetable nanoprobe for peroxynitrite sensing in living cells

1 reference

12 December 2020

The mitochondria-targeted imidazole substituted oleic acid 'TPP-IOA' affects mitochondrial bioenergetics and its protective efficacy in cells is influenced by cellular dependence on aerobic metabolism

1 reference

12 December 2020

Mitochondria targeting nano agents in cancer therapeutics (Review)

1 reference

12 December 2020

Photosensitizer-mediated mitochondria-targeting nanosized drug carriers: Subcellular targeting, therapeutic, and imaging potentials.

1 reference

12 December 2020

A novel mitochondria-targeted near-infrared fluorescence probe for ultrafast and ratiometric detection of SO2 derivatives in live cells.

1 reference

12 December 2020

A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells.

1 reference

12 December 2020

Mito-methyl coumarin, a novel mitochondria-targeted drug with great antitumor potential was synthesized

1 reference

12 December 2020

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications.

1 reference

12 December 2020

pH-Responsive de-PEGylated nanoparticles based on triphenylphosphine-quercetin self-assemblies for mitochondria-targeted cancer therapy.

1 reference

12 December 2020

10.1016/J.APSB.2018.05.006

Identifiers

DOI

1 reference

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10 April 2020

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10 April 2020

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