(Q90080170)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

review article

1 reference

title

Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story (English)

1 reference

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11 April 2020

8

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11 April 2020

author name string

Rand Naffouje

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Punita Grover

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Hongyang Yu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Arun Sendilnathan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Kara Wolfe

5

1 reference

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11 April 2020

Nazanin Majd

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Eric P Smith

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Toshiya Senda

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Satoshi Kofuji

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Atsuo T Sasaki

11

1 reference

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11 April 2020

publication date

11 September 2019

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11 April 2020

1 reference

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11 April 2020

volume

11

1 reference

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11 April 2020

issue

9

1 reference

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Creative Commons Attribution 4.0 International

11 April 2020

copyright license

start time

11 September 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Synthesis and antiviral activity of certain thiazole C-nucleosides

1 reference

12 December 2020

Action of bredinin on mammalian cells

1 reference

12 December 2020

Treatment Of Psoriasis With Oral Mycophenolic Acid

1 reference

12 December 2020

Antitumor activity of derivatives of mycophenolic acid

1 reference

12 December 2020

Politics and pellagra: the epidemic of pellagra in the U.S. in the early twentieth century

1 reference

12 December 2020

Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells

1 reference

12 December 2020

Increased inosine-5'-phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell lines

1 reference

12 December 2020

Antitumor activity of tiazofurin in human colon carcinoma HT-29

1 reference

12 December 2020

Inhibition by tiazofurin of inosine 5'-phosphate dehydrogenase (IMP DH) activity in extracts of ovarian carcinomas

1 reference

12 December 2020

Supratentorial malignant glioma: patterns of recurrence and implications for external beam local treatment

1 reference

12 December 2020

Clinical pharmacokinetic study of tiazofurin administered as a 1-hour infusion.

1 reference

12 December 2020

Expression of IMP dehydrogenase in differentiating HL-60 cells

1 reference

12 December 2020

Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen

1 reference

12 December 2020

Induction of cell differentiation in melanoma cells by inhibitors of IMP dehydrogenase: altered patterns of IMP dehydrogenase expression and activity.

1 reference

12 December 2020

Nucleosides and nucleotides. 96. Synthesis and antitumor activity of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives

1 reference

12 December 2020

In vitro immunosuppressive effects of mycophenolic acid and an ester pro-drug, RS-61443.

1 reference

12 December 2020

Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds

1 reference

12 December 2020

Clinical toxicity associated with tiazofurin

1 reference

12 December 2020

Bioavailability improvement of mycophenolic acid through amino ester derivatization

1 reference

12 December 2020

Phase I study of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).

1 reference

12 December 2020

IMP dehydrogenase: inhibition by the anti-leukemic drug, tiazofurin.

1 reference

12 December 2020

Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of inosine 5'-phosphate dehydrogenase activity.

1 reference

12 December 2020

[Phase I study and early phase II of SM-108 (4-carbamoylimidazolium-5-olate) in lung cancer. SM-108 Study Group]

1 reference

12 December 2020

Phase II study of SM-108 (4-carbamoylimidazolium-5-olate) in hematological malignancies

1 reference

12 December 2020

Growth inhibition and induction of phenotypic alterations by tiazofurin: differential effects on MCF-7 breast cancer and HBL-100 breast cell lines

1 reference

12 December 2020

Dual inhibitory effect of bredinin

1 reference

12 December 2020

Phase II study of tiazofurin (NSC 286193) in the treatment of advanced small cell bronchogenic carcinoma

1 reference

12 December 2020

Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase

1 reference

12 December 2020

Induction of erythroid differentiation and modulation of gene expression by tiazofurin in K-562 leukemia cells

1 reference

12 December 2020

A novel fibrillar structure in cultured cells detected by a monoclonal antibody

1 reference

12 December 2020

[Clinical trial of SM-108 in myeloproliferative disorders]

1 reference

12 December 2020

[Treatment of myelodysplastic syndrome using SM-108 in relation to stem cell kinetics]

1 reference

12 December 2020

Hematological and biochemical action of tiazofurin (NSC 286193) in a case of refractory acute myeloid leukemia.

1 reference

12 December 2020

Phase II trial of tiazofurin in recurrent squamous cell carcinoma of the head and neck.

1 reference

12 December 2020

Phase II study of tiazofurin in colorectal cancer: a National Cancer Institute of Canada Study

1 reference

12 December 2020

Selective sensitivity to tiazofurin of human leukemic cells.

1 reference

12 December 2020

Ribavirin aerosol approved for severe cases of RSV in infants and young children

1 reference

12 December 2020

Phase I trial of tiazofurin administered by i.v. bolus daily for 5 days, with pharmacokinetic evaluation.

1 reference

12 December 2020

Biochemical mechanisms of resistance to tiazofurin.

1 reference

12 December 2020

Phase I and pharmacokinetic study of tiazofurin (NSC 286193) administered by 5-day continuous infusion.

1 reference

12 December 2020

Phase I clinical study with pharmacokinetic analysis of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193) administered as a five-day infusion

1 reference

12 December 2020

Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).

1 reference

12 December 2020

Phase I and pharmacokinetic study of tiazofurin (TCAR, NSC 286193) administered by continuous infusion.

1 reference

12 December 2020

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

1 reference

12 December 2020

Mycophenolic acid: antiviral and antitumor properties

1 reference

12 December 2020

Antitumor activity of mycophenolic acid

1 reference

12 December 2020

Experimental antitumor activity and preclinical toxicology of mycophenolic acid

1 reference

12 December 2020

Studies on bredinin. I. Isolation, characterization and biological properties

1 reference

12 December 2020

Metabolism and biochemistry of mycophenolic acid

1 reference

12 December 2020

Immunosuppressive effect of mycophenolic acid.

1 reference

12 December 2020

Mycophenolic Acid: an Anti-cancer Compound with Unusual Properties

1 reference

12 December 2020

The inhibition of nucleic acid synthesis by mycophenolic acid

1 reference

12 December 2020

The conversion of 2-β-D-ribofuranosylthiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties

1 reference

12 December 2020

Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193).

1 reference

12 December 2020

Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193)--II. Relationship between dose level and biochemical effects in P388 leukemia in vivo.

1 reference

12 December 2020

Comparative in vitro studies of Tiazofurin and a selenazole analog.

1 reference

12 December 2020

Genetic and biochemical studies on the activation and cytotoxic mechanism of bredinin, a potent inhibitor of purine biosynthesis in mammalian cells.

1 reference

12 December 2020

Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide--V. Factors governing the response of murine tumors to tiazofurin

1 reference

12 December 2020

Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide)

1 reference

12 December 2020

Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity

1 reference

12 December 2020

The immunosuppressive mode of action of mizoribine

1 reference

12 December 2020

Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme

1 reference

12 December 2020

Tiazofurin: a new antitumor agent.

1 reference

12 December 2020

Novel nucleoside inhibitors of guanosine metabolism as antitumor agents.

1 reference

12 December 2020

Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin

1 reference

12 December 2020

Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent

1 reference

12 December 2020

Synthesis and antitumor activity of 2-beta-D-ribofuranosylselenazole-4- carboxamide and related derivatives

1 reference

12 December 2020

Immunosuppressive effect of bredinin on cell-mediated and humoral immune reactions in experimental animals

1 reference

12 December 2020

2-beta-D-Ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases.

1 reference

12 December 2020

Antitumor activities of newly synthesized 5-carbamoyl-1 H-imidazol-4yl 1-adamantanecarboxylate and 5-carbamoyl-1H-imidazol-4yl piperonylate

1 reference

12 December 2020

Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.

1 reference

12 December 2020

Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group

1 reference

12 December 2020

Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. European Mycophenolate Mofetil Cooperative Study Group

1 reference

12 December 2020

Physiological concentrations of purines and pyrimidines

1 reference

12 December 2020

Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.

1 reference

12 December 2020

Characterization of human type I and type II IMP dehydrogenases

1 reference

12 December 2020

Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase

1 reference

12 December 2020

Tissue-differential expression of two distinct genes for human IMP dehydrogenase (E.C.1.1.1.205).

1 reference

12 December 2020

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin.

1 reference

12 December 2020

Biochemical consequences of resistance to tiazofurin in human myelogenous leukemic K562 cells

1 reference

12 December 2020

Chromosomal localization and structure of the human type II IMP dehydrogenase gene (IMPDH2)

1 reference

12 December 2020

Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo

1 reference

12 December 2020

Phase II study of tiazofurin in gliomas in adults. A National Cancer Institute of Canada study

1 reference

12 December 2020

A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group

1 reference

12 December 2020

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

1 reference

12 December 2020

The structure of a domain common to archaebacteria and the homocystinuria disease protein

1 reference

12 December 2020

The antitumor effect of Tiazofurin (TR) consists of anti-proliferative and anti-invasive elements.

1 reference

12 December 2020

Biochemically targeted therapy of refractory leukemia and myeloid blast crisis of chronic granulocytic leukemia with Tiazofurin, a selective blocker of inosine 5'-phosphate dehydrogenase activity.

1 reference

12 December 2020

IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells.

1 reference

12 December 2020

Human colorectal carcinoma cells in vitro as a means to assess the metabolism of analogs of mycophenolic acid

1 reference

12 December 2020

Tacrolimus (FK506) and mycophenolate mofetil combination therapy versus tacrolimus in adult liver transplantation

1 reference

12 December 2020

Synthesis of a methylenebis(phosphonate) analogue of mycophenolic adenine dinucleotide: a glucuronidation-resistant MAD analogue of NAD.

1 reference

12 December 2020

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

1 reference

12 December 2020

Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design

1 reference

12 December 2020

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

1 reference

12 December 2020

Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells

1 reference

12 December 2020

Occurrence of cancers in immunosuppressed organ transplant recipients.

1 reference

12 December 2020

Biochemical analysis of the modular enzyme inosine 5'-monophosphate dehydrogenase

1 reference

12 December 2020

Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon

1 reference

12 December 2020

Domain architecture of the heme-independent yeast cystathionine beta-synthase provides insights into mechanisms of catalysis and regulation

1 reference

12 December 2020

Differential sensitivity of ovarian carcinoma cell lines to apoptosis induced by the IMPDH inhibitor benzamide riboside

1 reference

12 December 2020

Antitumor activity of benzamide riboside and its combination with cisplatin and staurosporine

1 reference

12 December 2020

Tiazofurine ICN Pharmaceuticals.

1 reference

12 December 2020

VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent

1 reference

12 December 2020

Tacrolimus versus cyclosporine after lung transplantation: a prospective, open, randomized two-center trial comparing two different immunosuppressive protocols

1 reference

12 December 2020

Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management

1 reference

12 December 2020

Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase

1 reference

12 December 2020

Toxicity and efficacy of benzamide riboside in cancer chemotherapy models

1 reference

12 December 2020

Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.

1 reference

12 December 2020

A modified approach to 2-(N-aryl)-1,3-oxazoles: application to the synthesis of the IMPDH inhibitor BMS-337197 and analogues

1 reference

12 December 2020

Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor

1 reference

12 December 2020

Enterohepatic recirculation: a powerful incentive for drug discovery in the inosine monophosphate dehydrogenase field

1 reference

12 December 2020

Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment

1 reference

12 December 2020

Cyclosporine A versus tacrolimus in combination with mycophenolate mofetil and steroids as primary immunosuppression after lung transplantation: One-year results of a 2-center prospective randomized trial

1 reference

12 December 2020

Merimepodib (Vertex).

1 reference

12 December 2020

Biosynthesis of nucleic acid purines. II. Role of hypoxanthine and xanthine compounds

1 reference

12 December 2020

Biosynthesis of nucleic acid purines. I. Formation of guanine from adenine compounds in bone marrow extracts

1 reference

12 December 2020

Association of the type of induction immunosuppression with posttransplant lymphoproliferative disorder, graft survival, and patient survival after primary kidney transplantation

1 reference

12 December 2020

Mycophenolate mofetil for myasthenia gravis: an analysis of efficacy, safety, and tolerability

1 reference

12 December 2020

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

1 reference

12 December 2020

Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata

1 reference

12 December 2020

Sequential therapies for proliferative lupus nephritis

1 reference

12 December 2020

De novo internal neoplasms after liver transplantation: increased risk and aggressive behavior in recent years?

1 reference

12 December 2020

Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part I. In vivo studies

1 reference

12 December 2020

Phase I clinical trial of the inosine monophosphate dehydrogenase inhibitor mycophenolate mofetil (cellcept) in advanced multiple myeloma patients.

1 reference

12 December 2020

Guanine nucleotide depletion induces differentiation and aberrant neurite outgrowth in human dopaminergic neuroblastoma lines: a model for basal ganglia dysfunction in Lesch-Nyhan disease.

1 reference

12 December 2020

Mycophenolate mofetil vs. azathioprine is associated with decreased acute rejection, late acute rejection, and risk for cardiovascular death in renal transplant recipients with pre-transplant diabetes

1 reference

12 December 2020

Mechanisms of action of mycophenolate mofetil

1 reference

12 December 2020

Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients.

1 reference

12 December 2020

Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway

1 reference

12 December 2020

Mycophenolate mofetil combination therapy improves long-term outcomes after liver transplantation in patients with and without hepatitis C.

1 reference

12 December 2020

Mechanism of action of interferon and ribavirin in treatment of hepatitis C

1 reference

12 December 2020

A randomized, double-blind, placebo-controlled dose-escalation trial of merimepodib (VX-497) and interferon-alpha in previously untreated patients with chronic hepatitis C.

1 reference

12 December 2020

Randomized controlled trial of pulse intravenous cyclophosphamide versus mycophenolate mofetil in the induction therapy of proliferative lupus nephritis

1 reference

12 December 2020

Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.

1 reference

12 December 2020

CBS domains: structure, function, and pathology in human proteins

1 reference

12 December 2020

Prospective registry-based observational cohort study of the long-term risk of malignancies in renal transplant patients treated with mycophenolate mofetil

1 reference

12 December 2020

The effect of benzamide riboside on the VX2 model of liver cancer in rabbits

1 reference

12 December 2020

Mycophenolic acid-induced replication arrest, differentiation markers and cell death of androgen-independent prostate cancer cells DU145.

1 reference

12 December 2020

Tacrolimus with mycophenolate mofetil (MMF) or sirolimus vs. cyclosporine with MMF in cardiac transplant patients: 1-year report.

1 reference

12 December 2020

Treatment of severe aplastic anaemia with combined immunosuppression: anti-thymocyte globulin, ciclosporin and mycophenolate mofetil

1 reference

12 December 2020

Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase

1 reference

12 December 2020

Mycophenolate mofetil and risk of developing malignancy after orthotopic heart transplantation: analysis of the transplant registry of the International Society for Heart and Lung Transplantation.

1 reference

12 December 2020

Gnidilatimonoein from Daphne mucronata induces differentiation and apoptosis in leukemia cell lines

1 reference

12 December 2020

Tumor-stroma interactions in pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption

1 reference

12 December 2020

Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

1 reference

12 December 2020

Effect of mycophenolate mofetil on pulmonary function in scleroderma-associated interstitial lung disease.

1 reference

12 December 2020

An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis.

1 reference

12 December 2020

Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase

1 reference

12 December 2020

Malignancy after solid organ transplantation: an overview

1 reference

12 December 2020

A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers

1 reference

12 December 2020

Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard-dose or reduced-dose tacrolimus in liver transplant recipients

1 reference

12 December 2020

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin.

1 reference

12 December 2020

Etanercept, mycophenolate, denileukin, or pentostatin plus corticosteroids for acute graft-versus-host disease: a randomized phase 2 trial from the Blood and Marrow Transplant Clinical Trials Network

1 reference

12 December 2020

Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents.

1 reference

12 December 2020

Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality

1 reference

12 December 2020

Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection

1 reference

12 December 2020

A prospective open-label study of mycophenolate mofetil for the treatment of diffuse systemic sclerosis

1 reference

12 December 2020

Mizoribine: a new approach in the treatment of renal disease

1 reference

12 December 2020

Mycophenolate mofetil reduces alveolar inflammation, acute rejection and graft loss due to bronchiolitis obliterans syndrome after lung transplantation

1 reference

12 December 2020

Diagnosis and management of autoimmune hepatitis

1 reference

12 December 2020

Consensus conference on clinical practice in chronic graft-versus-host disease (GVHD): first-line and topical treatment of chronic GVHD.

1 reference

12 December 2020

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

1 reference

12 December 2020

Mycophenolic acid; an antibiotic from Penicillium brevicompactum Dlerckx

1 reference

12 December 2020

Long-term experience of mycophenolate mofetil for treatment of diffuse cutaneous systemic sclerosis.

1 reference

12 December 2020

Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer

1 reference

12 December 2020

Enteric-coated mycophenolate sodium in de novo and maintenance kidney-pancreas transplant recipients

1 reference

12 December 2020

In vitro and in vivo characterization of AS2643361, a novel and highly potent inosine 5'-monophosphate dehydrogenase inhibitor

1 reference

12 December 2020

Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis

1 reference

12 December 2020

Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells

1 reference

12 December 2020

A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset

1 reference

12 December 2020

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

1 reference

12 December 2020

A preclinical and clinical study of mycophenolate mofetil in pancreatic cancer

1 reference

12 December 2020

Therapeutic effect of mizoribine on pemphigus vulgaris and pemphigus foliaceus

1 reference

12 December 2020

A second target of benzamide riboside: dihydrofolate reductase

1 reference

12 December 2020

Novel inhibitors of inosine monophosphate dehydrogenase in patent literature of the last decade

1 reference

12 December 2020

Dynamic reorganization of metabolic enzymes into intracellular bodies

1 reference

12 December 2020

Standards of care for treatment of recurrent glioblastoma--are we there yet?

1 reference

12 December 2020

Tacrolimus with mycophenolate mofetil or sirolimus compared with calcineurin inhibitor-free immunosuppression (sirolimus/mycophenolate mofetil) after heart transplantation: 5-year results

1 reference

12 December 2020

Myasthenia gravis: an update for the clinician

1 reference

12 December 2020

Molecular cell biology and immunobiology of mammalian rod/ring structures.

1 reference

12 December 2020

Glutamine deprivation initiates reversible assembly of mammalian rods and rings.

1 reference

12 December 2020

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

1 reference

12 December 2020

Imatinib: a breakthrough of targeted therapy in cancer

1 reference

12 December 2020

Ultrastructure of cytoplasmic and nuclear inosine-5'-monophosphate dehydrogenase 2 "rods and rings" inclusions.

1 reference

12 December 2020

Everolimus initiation and early calcineurin inhibitor withdrawal in heart transplant recipients: a randomized trial.

1 reference

12 December 2020

Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis

1 reference

12 December 2020

Cytoophidium assembly reflects upregulation of IMPDH activity.

1 reference

12 December 2020

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

1 reference

12 December 2020

Lack of cross-resistance to FF-10501, an inhibitor of inosine-5'-monophosphate dehydrogenase, in azacitidine-resistant cell lines selected from SKM-1 and MOLM-13 leukemia cell lines

1 reference

12 December 2020

A real-world study focused on the long-term efficacy of mycophenolate mofetil as first-line treatment of autoimmune hepatitis

1 reference

12 December 2020

Metabolic regulation via enzyme filamentation

1 reference

12 December 2020

'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway

1 reference

12 December 2020

Myricetin is a novel inhibitor of human inosine 5'-monophosphate dehydrogenase with anti-leukemia activity.

1 reference

12 December 2020

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial

1 reference

12 December 2020

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016).

1 reference

12 December 2020

Higher order structures in purine and pyrimidine metabolism

1 reference

12 December 2020

Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS).

1 reference

12 December 2020

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma.

1 reference

12 December 2020

Anti-cancer activity of myricetin against human papillary thyroid cancer cells involves mitochondrial dysfunction-mediated apoptosis.

1 reference

12 December 2020

A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases.

1 reference

12 December 2020

Myricetin induces apoptosis and enhances chemosensitivity in ovarian cancer cells

1 reference

12 December 2020

Preclinical activity of FF-10501-01, a novel inosine-5'-monophosphate dehydrogenase inhibitor, in acute myeloid leukemia.

1 reference

12 December 2020

mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability

1 reference

12 December 2020

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens

1 reference

12 December 2020

Efficacy of ribavirin against malignant glioma cell lines: Follow-up study

1 reference

12 December 2020

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia.

1 reference

12 December 2020

Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15 cells.

1 reference

12 December 2020

Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide.

1 reference

12 December 2020

Impact of intensive dosing of mycophenolate on pancreas allograft survival

1 reference

12 December 2020

Current status and future directions of cancer immunotherapy.

1 reference

12 December 2020

IMP/GTP balance modulates cytoophidium assembly and IMPDH activity.

1 reference

12 December 2020

Inhibition of eukaryotic translation initiation factor 4E is effective against chemo-resistance in colon and cervical cancer

1 reference

12 December 2020

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

1 reference

12 December 2020

The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction

1 reference

12 December 2020

Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy

1 reference

12 December 2020

Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia

1 reference

12 December 2020

Myricetin inhibits panel of kinases implicated in tumorigenesis

1 reference

12 December 2020

Mizoribine is as Effective as Methotrexate for the Treatment of Polymyalgia Rheumatica: A Retrospective Case Series Analysis

1 reference

12 December 2020

A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity

1 reference

12 December 2020

Usefulness of mizoribine administration in children with frequently relapsing nephrotic syndrome, and the relationship between pharmacokinetic parameters and efficacy: a multicenter prospective cohort study in China

1 reference

12 December 2020

Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP

1 reference

12 December 2020

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

1 reference

12 December 2020

Identifiers

DOI

10.3390/CANCERS11091346

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514446%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

PubMed publication ID

31514446

1 reference