(Q90460856)

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14 April 2020

title

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers (English)

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14 April 2020

13

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14 April 2020

Trudy G Oliver

16

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14 April 2020

Zeping Hu

18

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14 April 2020

author name string

Fang Huang

1

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14 April 2020

Min Ni

2

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14 April 2020

Milind D Chalishazar

3

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14 April 2020

Kenneth E Huffman

4

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14 April 2020

Jiyeon Kim

5

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14 April 2020

Ling Cai

6

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14 April 2020

Xiaolei Shi

7

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14 April 2020

Feng Cai

8

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14 April 2020

Lauren G Zacharias

9

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14 April 2020

Abbie S Ireland

10

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14 April 2020

Kailong Li

11

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14 April 2020

Wen Gu

12

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14 April 2020

Xin Liu

14

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14 April 2020

Adi F Gazdar

15

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14 April 2020

John D Minna

17

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14 April 2020

Ralph J DeBerardinis

19

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14 April 2020

publication date

28 June 2018

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14 April 2020

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14 April 2020

volume

28

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14 April 2020

issue

3

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14 April 2020

page(s)

369-382.e5

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myc family DNA amplification in tumors and tumor cell lines from patients with small-cell lung cancer

14 April 2020

cites work

1 reference

12 December 2020

Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties

1 reference

12 December 2020

Mizoribine and mycophenolate mofetil

1 reference

12 December 2020

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

1 reference

12 December 2020

Inhibitors of de novo nucleotide biosynthesis as drugs

1 reference

12 December 2020

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

1 reference

12 December 2020

Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: analysis of a nationwide study in Japan

1 reference

12 December 2020

IMP dehydrogenase: structural schizophrenia and an unusual base

1 reference

12 December 2020

Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database

1 reference

12 December 2020

Mycophenolate mofetil inhibits tumor growth and angiogenesis in vitro but has variable antitumor effects in vivo, possibly related to bioavailability

1 reference

12 December 2020

Global regulation of nucleotide biosynthetic genes by c-Myc

1 reference

12 December 2020

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells

1 reference

12 December 2020

Treatment of extensive-stage small cell lung carcinoma: current status and future prospects

1 reference

12 December 2020

Mizoribine: a new approach in the treatment of renal disease

1 reference

12 December 2020

Surveillance epidemiology and end results evaluation of the role of surgery for stage I small cell lung cancer.

1 reference

12 December 2020

Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma

1 reference

12 December 2020

Advances in neuroendocrine lung tumors

1 reference

12 December 2020

Neuroendocrine tumors of the lung: an update

1 reference

12 December 2020

Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogene

1 reference

12 December 2020

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

1 reference

12 December 2020

GTP depletion synergizes the anti-proliferative activity of chemotherapeutic agents in a cell type-dependent manner

1 reference

12 December 2020

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

12 December 2020

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

1 reference

12 December 2020

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

1 reference

12 December 2020

Transcriptional amplification in tumor cells with elevated c-Myc.

1 reference

12 December 2020

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

1 reference

12 December 2020

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

1 reference

12 December 2020

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer

1 reference

12 December 2020

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

1 reference

12 December 2020

MYC, metabolism, cell growth, and tumorigenesis.

1 reference

12 December 2020

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

1 reference

12 December 2020

Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing

1 reference

12 December 2020

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

1 reference

12 December 2020

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

1 reference

12 December 2020

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

1 reference

12 December 2020

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung

1 reference

12 December 2020

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1.

1 reference

12 December 2020

A roadmap for interpreting (13)C metabolite labeling patterns from cells

1 reference

12 December 2020

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

1 reference

12 December 2020

Metabolic pathways promoting cancer cell survival and growth

1 reference

12 December 2020

Comprehensive genomic profiles of small cell lung cancer

1 reference

12 December 2020

MYC, Metabolism, and Cancer

1 reference

12 December 2020

Drug target molecules to guide immunosuppression

1 reference

12 December 2020

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

1 reference

12 December 2020

Metabolic Heterogeneity in Human Lung Tumors.

1 reference

12 December 2020

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

1 reference

12 December 2020

Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

1 reference

12 December 2020

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

1 reference

12 December 2020

Using MetaboAnalyst 3.0 for Comprehensive Metabolomics Data Analysis

1 reference

12 December 2020

MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.

1 reference

12 December 2020

Understanding the Intersections between Metabolism and Cancer Biology

1 reference

12 December 2020

NOTCH1-mutated chronic lymphocytic leukemia cells are characterized by a MYC-related overexpression of nucleophosmin 1 and ribosome-associated components.

1 reference

12 December 2020

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

1 reference

12 December 2020

mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability

1 reference

12 December 2020

10.1016/J.CMET.2018.06.005

Identifiers

DOI

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14 April 2020

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14 April 2020

PubMed publication ID

30043754

1 reference