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MYC, metabolism, cell growth, and tumorigenesis.
scientific article published on August 2013
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Europe PubMed Central
PMCID
3721271
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
title
MYC, metabolism, cell growth, and tumorigenesis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
main subject
cell growth
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inferred from title
author
Chi V. Dang
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3721271
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
author name string
Chi V Dang
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1
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Europe PubMed Central
PMCID
3721271
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17 August 2017
publication date
1 August 2013
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Europe PubMed Central
PMCID
3721271
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
published in
Cold Spring Harbor Perspectives in Medicine
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stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
volume
3
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Europe PubMed Central
PMCID
3721271
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth
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Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
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Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
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Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis
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29 September 2017
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
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Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
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LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis
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Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha
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29 September 2017
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
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29 September 2017
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation
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29 September 2017
Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry
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29 September 2017
Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway.
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29 September 2017
c-Myc regulates transcriptional pause release
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29 September 2017
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
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29 September 2017
MYC as a regulator of ribosome biogenesis and protein synthesis
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29 September 2017
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
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29 September 2017
Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation
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The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer
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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
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Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6.
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29 September 2017
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
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29 September 2017
A role for E2F activities in determining the fate of Myc-induced lymphomagenesis
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29 September 2017
c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry
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29 September 2017
LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer
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29 September 2017
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
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29 September 2017
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29 September 2017
MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc
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29 September 2017
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
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29 September 2017
Myc's broad reach
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29 September 2017
miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression
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29 September 2017
Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells
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29 September 2017
Global regulation of nucleotide biosynthetic genes by c-Myc
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29 September 2017
Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line
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29 September 2017
Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo
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29 September 2017
Widespread microRNA repression by Myc contributes to tumorigenesis
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29 September 2017
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.
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29 September 2017
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
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29 September 2017
Myc deletion rescues Apc deficiency in the small intestine
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29 September 2017
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
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29 September 2017
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
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29 September 2017
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
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29 September 2017
c-Myc-regulated microRNAs modulate E2F1 expression
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29 September 2017
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
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29 September 2017
Developmental context determines latency of MYC-induced tumorigenesis
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29 September 2017
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays
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29 September 2017
dMyc is required for larval growth and endoreplication in Drosophila
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29 September 2017
An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets
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29 September 2017
c-MYC apoptotic function is mediated by NRF-1 target genes
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29 September 2017
Direct activation of RNA polymerase III transcription by c-Myc
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Overexpression of c-Myc alters G(1)/S arrest following ionizing radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Repression of p15INK4b expression by Myc through association with Miz-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Identification of CDK4 as a target of c-MYC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Control of cell growth by c-Myc in the absence of cell division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
c-Myc overexpression uncouples DNA replication from mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
A unique glucose-dependent apoptotic pathway induced by c-Myc
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Induction of apoptosis in fibroblasts by c-myc protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
29 September 2017
Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
27 June 2018
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
27 June 2018
Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
27 June 2018
Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
4 September 2018
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
4 September 2018
Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
4 September 2018
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
4 September 2018
Drosophila myc regulates cellular growth during development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721271
retrieved
4 September 2018
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23906881
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/CSHPERSPECT.A014217
1 reference
stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PMCID
3721271
1 reference
stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PubMed ID
23906881
1 reference
stated in
Europe PubMed Central
PMCID
3721271
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906881%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
ResearchGate publication ID
254264228
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