(Q90341588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30526882%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis (English)

1 reference

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13 April 2020

1 reference

11

George Sandusky

1 reference

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13 April 2020

author name string

Zhigang Cai

1

1 reference

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13 April 2020

Jonathan J Kotzin

2

1 reference

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13 April 2020

Baskar Ramdas

3

1 reference

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13 April 2020

Sisi Chen

4

1 reference

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13 April 2020

Sai Nelanuthala

5

1 reference

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13 April 2020

Lakshmi Reddy Palam

6

1 reference

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13 April 2020

Ruchi Pandey

7

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13 April 2020

Raghuveer Singh Mali

8

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13 April 2020

Yan Liu

9

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13 April 2020

Mark R Kelley

10

1 reference

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13 April 2020

Morvarid Mohseni

12

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13 April 2020

Adam Williams

13

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13 April 2020

Jorge Henao-Mejia

14

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13 April 2020

Reuben Kapur

15

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13 April 2020

publication date

1 December 2018

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13 April 2020

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13 April 2020

volume

23

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13 April 2020

issue

6

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13 April 2020

page(s)

833-849.e5

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

13 April 2020

cites work

1 reference

12 December 2020

Cancer risk in patients with inflammatory bowel disease: a population-based study

1 reference

12 December 2020

Bacterial infection promotes colon tumorigenesis in Apc(Min/+) mice

1 reference

12 December 2020

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

12 December 2020

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

1 reference

12 December 2020

LPS/TLR4 signal transduction pathway

1 reference

12 December 2020

Cancer-related inflammation

1 reference

12 December 2020

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

1 reference

12 December 2020

IFNalpha activates dormant haematopoietic stem cells in vivo.

1 reference

12 December 2020

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis

1 reference

12 December 2020

Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).

1 reference

12 December 2020

Awakening dormant haematopoietic stem cells

1 reference

12 December 2020

Immunity, Inflammation, and Cancer

1 reference

12 December 2020

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection

1 reference

12 December 2020

Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression.

1 reference

12 December 2020

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

1 reference

12 December 2020

Hallmarks of Cancer: The Next Generation

1 reference

12 December 2020

Apurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophages.

1 reference

12 December 2020

Chronic exposure to a TLR ligand injures hematopoietic stem cells

1 reference

12 December 2020

Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes

1 reference

12 December 2020

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

1 reference

12 December 2020

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

1 reference

12 December 2020

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

1 reference

12 December 2020

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

1 reference

12 December 2020

Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response

1 reference

12 December 2020

Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells

1 reference

12 December 2020

IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development

1 reference

12 December 2020

Dnmt3a is essential for hematopoietic stem cell differentiation

1 reference

12 December 2020

Demand-adapted regulation of early hematopoiesis in infection and inflammation

1 reference

12 December 2020

Clonal evolution in cancer

1 reference

12 December 2020

Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?

1 reference

12 December 2020

The role of mutations in epigenetic regulators in myeloid malignancies

1 reference

12 December 2020

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

1 reference

12 December 2020

FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm

1 reference

12 December 2020

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

1 reference

12 December 2020

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

1 reference

12 December 2020

APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival

1 reference

12 December 2020

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

1 reference

12 December 2020

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

1 reference

12 December 2020

Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis

1 reference

12 December 2020

Emergency granulopoiesis

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12 December 2020

Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?

1 reference

12 December 2020

Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis

1 reference

12 December 2020

Clone wars--the emergence of neoplastic blood-cell clones with aging.

1 reference

12 December 2020

1 reference

12 December 2020

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

1 reference

12 December 2020

Preleukemia: the normal side of cancer

1 reference

12 December 2020

IL-6 as a keystone cytokine in health and disease

1 reference

12 December 2020

Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cells

1 reference

12 December 2020

Regulation of stress-induced hematopoiesis

1 reference

12 December 2020

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

1 reference

12 December 2020

Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm

1 reference

12 December 2020

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors

1 reference

12 December 2020

How hematopoietic stem/progenitors and their niche sense and respond to infectious stress

1 reference

12 December 2020

Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both

1 reference

12 December 2020

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

1 reference

12 December 2020

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

1 reference

12 December 2020

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

1 reference

12 December 2020

The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia

1 reference

12 December 2020

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

1 reference

12 December 2020

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

1 reference

12 December 2020

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.

1 reference

12 December 2020

An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis.

1 reference

12 December 2020

Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.

1 reference

12 December 2020

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

1 reference

12 December 2020

10.1016/J.STEM.2018.10.013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30526882%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30526882%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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