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FAM35A/SHLD2/RINN2: A Novel Determinant of DSB Repair Pathway Choice and Genome Stability in Cancer
scientific article published on 19 April 2020
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Europe PubMed Central
PubMed publication ID
32306447
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
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26 April 2020
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title
FAM35A/SHLD2/RINN2: A Novel Determinant of DSB Repair Pathway Choice and Genome Stability in Cancer
(English)
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Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 April 2020
main subject
genome stability
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Junya Tomida
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4
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Junya Tomida
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Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
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26 April 2020
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Kylie Fackrell
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1
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Europe PubMed Central
PubMed publication ID
32306447
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
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26 April 2020
LoriAnn Bobins
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2
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PubMed publication ID
32306447
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retrieved
26 April 2020
Parul
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3
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Europe PubMed Central
PubMed publication ID
32306447
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26 April 2020
publication date
19 April 2020
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Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 April 2020
published in
Environmental and Molecular Mutagenesis
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stated in
Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 April 2020
cites work
Chromosome aberrations in solid tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
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inferred from DOI database lookup
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage response genes and the development of cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of MAD2B and other mitotic spindle checkpoint genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic landscape of DNA repair genes in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-homologous DNA end joining and alternative pathways to double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATR: an essential regulator of genome integrity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RIF1 in DNA break repair pathway choice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An OB-fold complex controls the repair pathways for DNA double-strand breaks
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-damage response in human biology and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systematic and quantitative assessment of the ubiquitin-modified proteome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NBS1 and multiple regulations of DNA damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulators of homologous recombination repair as novel targets for cancer treatment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular biology. Shielding broken DNA for a quick fix.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage sensing by the ATM and ATR kinases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The identification of FANCD2 DNA binding domains reveals nuclear localization sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The shieldin complex mediates 53BP1-dependent DNA repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor genetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A critical function of Mad2l2 in primordial germ cell development of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shieldin – the protector of DNA ends
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Principles of tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary immunodeficiencies associated with DNA-repair disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosomal stability and the DNA double-stranded break connection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Do DNA Double-Strand Breaks Drive Aging?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA repair disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
53BP1 regulates DSB repair using Rif1 to control 5' end resection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEM.22379
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EM.22379
1 reference
stated in
Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 April 2020
PubMed publication ID
32306447
1 reference
stated in
Europe PubMed Central
PubMed publication ID
32306447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32306447%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 April 2020
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