(Q92977826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

review article

4 references

14 September 2020

8 February 2021

3 October 2022

Molecular mechanisms of ferroptosis and its role in cancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference

14 September 2020

1 reference

1 reference

2 references

8 February 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Ying Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Jianxun Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

author name string

Wei Ding

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Xiaoyu Ji

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Xiang Ao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Wanpeng Yu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

publication date

24 June 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular and Molecular Medicine

2 May 2020

1 August 2019

3 references

14 September 2020

8 February 2021

3 October 2022

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

14 September 2020

8 February 2021

3 October 2022

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

page(s)

4900-4912

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

2 May 2020

copyright license

3 references

14 September 2020

8 February 2021

3 October 2022

0 references

Ferroptosis: an iron-dependent form of nonapoptotic cell death

1 reference

The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-) : cystine supplier and beyond

9 October 2020

1 reference

Glutathione--a review on its role and significance in Parkinson's disease

9 October 2020

1 reference

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

9 October 2020

1 reference

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

9 October 2020

1 reference

RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels

9 October 2020

1 reference

Regulation of ferroptotic cancer cell death by GPX4

9 October 2020

1 reference

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

9 October 2020

1 reference

9 October 2020

Glutathione peroxidase

1 reference

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

9 October 2020

1 reference

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

9 October 2020

1 reference

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

9 October 2020

1 reference

Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death

9 October 2020

1 reference

Glutaminolysis and Transferrin Regulate Ferroptosis

9 October 2020

1 reference

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.

9 October 2020

1 reference

Glutaminolysis and autophagy in cancer

9 October 2020

1 reference

miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma

9 October 2020

1 reference

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

9 October 2020

1 reference

Role of Mitochondria in Ferroptosis

9 October 2020

1 reference

Polyunsaturated fatty acids as antioxidants.

9 October 2020

1 reference

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

9 October 2020

1 reference

Ferroptosis: Oxidized PEs trigger death.

9 October 2020

1 reference

Mammalian long-chain acyl-CoA synthetases

9 October 2020

1 reference

Acyl-CoA:lysophospholipid acyltransferases

9 October 2020

1 reference

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

9 October 2020

1 reference

Toxicity of iron and hydrogen peroxide: the Fenton reaction

9 October 2020

1 reference

The role of iron in the initiation of lipid peroxidation

9 October 2020

1 reference

9 October 2020

1 reference

Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.

9 October 2020

1 reference

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

9 October 2020

1 reference

Ferritin, cellular iron storage and regulation

9 October 2020

1 reference

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents.

9 October 2020

1 reference

Programmed cell death via mitochondria: different modes of dying.

9 October 2020

1 reference

Ferroptosis as a target for protection against cardiomyopathy

9 October 2020

1 reference

Ferroptosis is an autophagic cell death process

9 October 2020

1 reference

An essential role for functional lysosomes in ferroptosis of cancer cells.

9 October 2020

1 reference

Ferroptosis is a lysosomal cell death process

9 October 2020

1 reference

Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts

9 October 2020

1 reference

Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

9 October 2020

1 reference

Release of iron from ferritin requires lysosomal activity

9 October 2020

1 reference

Autophagy promotes ferroptosis by degradation of ferritin

9 October 2020

1 reference

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

9 October 2020

1 reference

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.

9 October 2020

1 reference

Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5

9 October 2020

1 reference

Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.

9 October 2020

1 reference

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.

9 October 2020

1 reference

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

9 October 2020

1 reference

A novel transcription mechanism activated by ethanol: induction of Slc7a11 gene expression via inhibition of the DNA-binding activity of transcriptional repressor octamer-binding transcription factor 1 (OCT-1)

9 October 2020

1 reference

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

9 October 2020

1 reference

Ferroptosis as a p53-mediated activity during tumour suppression

9 October 2020

1 reference

Ferroptosis in p53-dependent oncosuppression and organismal homeostasis

9 October 2020

1 reference

Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

9 October 2020

1 reference

Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

9 October 2020

1 reference

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.

9 October 2020

1 reference

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

9 October 2020

1 reference

Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway

9 October 2020

1 reference

Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron.

9 October 2020

1 reference

Heme Oxygenase-1 Mitigates Ferroptosis in Renal Proximal Tubule Cells.

9 October 2020

1 reference

A Dual Role of Heme Oxygenase-1 in Cancer Cells

9 October 2020

1 reference

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

9 October 2020

1 reference

FANCD2 protects against bone marrow injury from ferroptosis.

9 October 2020

1 reference

AMPK regulates autophagy by phosphorylating BECN1 at threonine 388.

9 October 2020

1 reference

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity

9 October 2020

1 reference

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

9 October 2020

1 reference

Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells.

9 October 2020

1 reference

Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

9 October 2020

1 reference

Critical role of ABCG2 in ALA-photodynamic diagnosis and therapy of human brain tumor

9 October 2020

1 reference

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

9 October 2020

1 reference

Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

9 October 2020

1 reference

Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate

9 October 2020

1 reference

Iron addiction: a novel therapeutic target in ovarian cancer

9 October 2020

1 reference

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

9 October 2020

1 reference

Expression of selected gene for acquired drug resistance to EGFR-TKI in lung adenocarcinoma.

9 October 2020

1 reference

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

9 October 2020

1 reference

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

9 October 2020

1 reference

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

9 October 2020

1 reference

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

9 October 2020

1 reference

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

9 October 2020

1 reference

Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer.

9 October 2020

1 reference

HSPB1 as a novel regulator of ferroptotic cancer cell death

9 October 2020

1 reference

miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma.

9 October 2020

1 reference

Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion

9 October 2020

1 reference

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

9 October 2020

1 reference

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

9 October 2020

1 reference

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

9 October 2020

1 reference

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

9 October 2020

1 reference

Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells

9 October 2020

1 reference

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

9 October 2020

1 reference

Ferroptosis: A Novel Anti-Tumor Action for Cisplatin.

9 October 2020

1 reference

The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

9 October 2020

1 reference

Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death

9 October 2020

1 reference

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

9 October 2020

1 reference

Mutational and Expressional Analyses of NRF2 and KEAP1 in Sarcomas

9 October 2020

0 references

Knockdown of ferroportin accelerates erastin-induced ferroptosis in neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Antisense lncRNA As-SLC7A11 suppresses epithelial ovarian cancer progression mainly by targeting SLC7A11.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Sorafenib induces ferroptosis in human cancer cell lines originating from different solid tumors.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Mutational and expressional analyses of NRF2 and KEAP1 in sarcomas.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Menin associates with FANCD2, a protein involved in repair of DNA damage

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro. Role of the mixed disulfide of 2-mercaptoethanol and cysteine

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6653007

11 February 2021

Identifiers

DOI

10.1111/JCMM.14511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31232522%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference