(Q95301171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

title

Structure of replicating SARS-CoV-2 polymerase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

EXC 2067: Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells (MBExC)

24 May 2020

sponsor

0 references

RU2848: "Nanoscale Architecture and Heterogeneity of the Mitochondrial Inner Membrane"

0 references

1 reference

RNA-directed RNA polymerase [SARS-CoV-2]

1 reference

based on heuristic

inferred from abstract

Non-structural protein nsp8 [SARS-CoV-2]

1 reference

based on heuristic

inferred from abstract

Non-structural protein 7 [SARS-CoV-2]

1 reference

based on heuristic

inferred from abstract

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

Goran Kokic

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

Lucas Farnung

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

Dimitry Tegunov

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

Patrick Cramer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

author name string

Christian Dienemann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

language of work or name

English

0 references

publication date

21 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

https://mbexc.uni-goettingen.de/literature/publications/44

24 May 2020

official website

0 references

https://for2848.gwdguser.de/literature/publications/22

0 references

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses

24 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Hopes rise for coronavirus drug remdesivir

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

A new coronavirus associated with human respiratory disease in China

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

A pneumonia outbreak associated with a new coronavirus of probable bat origin

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Nucleosides for the treatment of respiratory RNA virus infections.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Race to find COVID-19 treatments accelerates

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

PCNA, the maestro of the replication fork

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Architecture and RNA binding of the human negative elongation factor.

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Automated electron microscope tomography using robust prediction of specimen movements

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Real-time cryo-electron microscopy data preprocessing with Warp

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Features and development of Coot

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Real-space refinement in PHENIX for cryo-EM and crystallography

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

Enhancing UCSF Chimera through web services

13 August 2020

1 reference

https://api.crossref.org/works/10.1038/S41586-020-2368-8

10.1038/S41586-020-2368-8

13 August 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json

24 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32438371%20AND%20SRC:MED&resulttype=core&format=json