(Q97687171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

title

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

Lars Pache

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

Sebastian Burgstaller-Muehlbacher

26 July 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

Michael Schotsaert

23

1 reference

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26 July 2020

Luis Martinez-Sobrido

28

1 reference

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26 July 2020

Kris M White

30

1 reference

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26 July 2020

Randy A. Albrecht

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

Andrew D. Mesecar

36

1 reference

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26 July 2020

Ren Sun

39

1 reference

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26 July 2020

Andrew I. Su

41

1 reference

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26 July 2020

Adolfo García-Sastre

42

1 reference

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26 July 2020

Arnab K Chatterjee

43

1 reference

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26 July 2020

Yuen Kwok-yung

44

1 reference

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26 July 2020

Sumit K Chanda

45

1 reference

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26 July 2020

12

Jasper Fuk-Woo Chan

1 reference

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26 July 2020

40

Peter G Schultz

1 reference

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26 July 2020

24

Lisa Miorin

1 reference

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26 July 2020

26

Thomas P Zwaka

1 reference

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26 July 2020

2

Shuofeng Yuan

1 reference

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26 July 2020

13

Jianli Cao

1 reference

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26 July 2020

27

Ko-Yung Sit

1 reference

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26 July 2020

11

Max W Chang

1 reference

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26 July 2020

22

Raveen Rathnasinghe

1 reference

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26 July 2020

Paul Jesús Tejada Llacsa

8

object named as

Paul D De Jesus

1 reference

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26 July 2020

21

Angela Choi

1 reference

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26 July 2020

4

Laura Martin-Sancho

1 reference

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26 July 2020

20

Courtney Nguyen

1 reference

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26 July 2020

15

Kristina M Herbert

1 reference

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26 July 2020

10

Mitchell V Hull

1 reference

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26 July 2020

25

Marion Dejosez

1 reference

26 July 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

author name string

Laura Riva

1

1 reference

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26 July 2020

Naoko Matsunaga

5

1 reference

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26 July 2020

Peter Teriete

9

1 reference

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26 July 2020

Vincent Kwok-Man Poon

14

1 reference

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26 July 2020

Kuoyuan Cheng

16

1 reference

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26 July 2020

Tu-Trinh H Nguyen

17

1 reference

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26 July 2020

Andrey Rubanov

18

1 reference

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26 July 2020

Yuan Pu

19

1 reference

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26 July 2020

Wen-Chun Liu

29

1 reference

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26 July 2020

Mackenzie E Chapman

31

1 reference

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26 July 2020

Emma K Lendy

32

1 reference

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26 July 2020

Richard J Glynne

33

1 reference

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26 July 2020

Eytan Ruppin

35

1 reference

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26 July 2020

Jeffrey R Johnson

37

1 reference

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26 July 2020

Christopher Benner

38

1 reference

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26 July 2020

publication date

24 July 2020

1 reference

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26 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation

26 July 2020

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PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling

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7 January 2021

First Clinical Study Using HCV Protease Inhibitor Danoprevir to Treat Naive and Experienced COVID-19 Patients

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7 January 2021

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

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7 January 2021

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7 January 2021

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

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7 January 2021

The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors

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7 January 2021

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

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7 January 2021

A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis

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7 January 2021

Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis

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7 January 2021

Drug repositioning for personalized medicine.

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7 January 2021

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

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7 January 2021

Virus Isolation from the First Patient with SARS-CoV-2 in Korea

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7 January 2021

Consistent detection of 2019 novel coronavirus in saliva

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7 January 2021

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection

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7 January 2021

Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry

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7 January 2021

HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

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7 January 2021

Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

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7 January 2021

Nelfinavir Is Active Against SARS-CoV-2 in Vero E6 Cells

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7 January 2021

Virtual screening for finding natural inhibitor against cathepsin-L for SARS therapy.

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7 January 2021

Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain

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7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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7 January 2021

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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7 January 2021

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

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7 January 2021

A Single-cell Atlas of the Human Healthy Airways

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7 January 2021

Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

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7 January 2021

Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)

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7 January 2021

Cardiovascular risks of hydroxychloroquine in treatment and prophylaxis of COVID-19 patients: A scientific statement from the Indian Heart Rhythm Society

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7 January 2021

The Use of Antimalarial Drugs against Viral Infection

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7 January 2021

A TIBO derivative, R82913, is a potent inhibitor of HIV-1 reverse transcriptase with heteropolymer templates

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7 January 2021

Pharmacokinetics of R 82913 in AIDS patients: a phase I dose-finding study of oral administration compared with intravenous infusion

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7 January 2021

Clofazimine: a review of its use in leprosy and Mycobacterium avium complex infection.

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7 January 2021

Development of novel entry inhibitors targeting emerging viruses

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7 January 2021

Processing of Capsid Protein by Cathepsin L Plays a Crucial Role in Replication of Japanese Encephalitis Virus in Neural and Macrophage Cells

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7 January 2021

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

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7 January 2021

Cathepsin B & L are not required for ebola virus replication

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7 January 2021

Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study

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7 January 2021

Effect of ONO-5334 on bone mineral density and biochemical markers of bone turnover in postmenopausal osteoporosis: 2-year results from the OCEAN study.

1 reference

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7 January 2021

The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.

1 reference

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7 January 2021

Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.

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7 January 2021

Snx10 and PIKfyve are required for lysosome formation in osteoclasts

1 reference

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7 January 2021

Mavyret: A Pan-Genotypic Combination Therapy for the Treatment of Hepatitis C InfectionPublished as part of the Biochemistry series "Biochemistry to Bedside".

1 reference

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7 January 2021

New anti-HCV drug combinations: who will benefit?

1 reference

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7 January 2021

Current status and prospects of HIV treatment

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7 January 2021

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

1 reference

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7 January 2021

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study

1 reference

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7 January 2021

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

1 reference

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7 January 2021

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

1 reference

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7 January 2021

STAR: ultrafast universal RNA-seq aligner

1 reference

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7 January 2021

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

1 reference

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7 January 2021

Molecular signatures database (MSigDB) 3.0.

1 reference

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7 January 2021

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

1 reference

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7 January 2021

Broad-spectrum inhibition of coronavirus main and papain-like proteases by HCV drugs

1 reference

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7 January 2021

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

1 reference

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7 January 2021

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

1 reference

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7 January 2021

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

1 reference

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7 January 2021

Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells

1 reference

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7 January 2021

Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix.

1 reference

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7 January 2021

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

1 reference

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7 January 2021

10.1038/S41586-020-2577-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32707573%20AND%20SRC:MED&resulttype=core&format=json

26 July 2020

1 reference