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Drug repositioning for personalized medicine.
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Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
title
Drug repositioning for personalized medicine
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
main subject
drug repositioning
1 reference
based on heuristic
inferred from title
personalized medicine
1 reference
based on heuristic
inferred from title
author
Steven Jones
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author name string
Yvonne Y Li
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
publication date
30 March 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
published in
Genome Medicine
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stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
volume
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
page(s)
27
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Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
exact match
https://scigraph.springernature.com/pub.10.1186/gm326
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
TarFisDock: a web server for identifying drug targets with docking approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Global mapping of pharmacological space
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Screening in a spirit haunted world
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Virtual ligand screening: strategies, perspectives and limitations
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
What do we know about duloxetine's mode of action? Evidence from animals to humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Statistical practice in high-throughput screening data analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
DrugBank: a comprehensive resource for in silico drug discovery and exploration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
From genomics to chemical genomics: new developments in KEGG
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Drug discovery: playing dirty
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
A small molecule-kinase interaction map for clinical kinase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Imatinib as a paradigm of targeted therapies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Can the pharmaceutical industry reduce attrition rates?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Drug repositioning: identifying and developing new uses for existing drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
The protein kinase complement of the human genome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Molecular portraits of human breast tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Drug discovery: a historical perspective
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Pharmacogenomics: translating functional genomics into rational therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
The biology of chronic myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
1 October 2017
Crizotinib--latest champion in the cancer wars?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
29 June 2018
Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
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29 June 2018
International group seeks to dispel incontinence "taboo".
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
29 June 2018
Crizotinib.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
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22 September 2018
Trial watch: Phase II failures: 2008-2010.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
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22 September 2018
Phase III and submission failures: 2007–2010
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
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22 September 2018
Rare diseases, orphan drugs and their regulation: questions and misconceptions
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Saving lives with accurate HER2 testing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Computational approaches for drug repositioning and combination therapy design.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Mechanisms of Resistance to Imatinib and Second-Generation Tyrosine Inhibitors in Chronic Myeloid Leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Lessons from 60 years of pharmaceutical innovation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Paul Ehrlich's magic bullet concept: 100 years of progress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
IDMap: facilitating the detection of potential leads with therapeutic targets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
The presence of a BCR-ABL mutant allele in CML does not always explain clinical resistance to imatinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Adopting orphan drugs--two dozen years of treating rare diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Cellular targets of gefitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
22 September 2018
Identification of small molecules enhancing autophagic function from drug network analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
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21 October 2018
Preparing for Precision Medicine
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446277
retrieved
5 December 2018
Bupropion and naltrexone: a review of their use individually and in combination for the treatment of obesity
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A novel structure-based virtual screening model for the hERG channel blockers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Why big pharma needs to learn the three 'R's
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Trial watch: Adaptive BATTLE trial uses biomarkers to guide lung cancer treatment
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
How melanomas bypass new therapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Vemurafenib
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
KRAS mutation detection: a new look at an old gene
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Duloxetine use in painful conditions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The bitterest pill
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22494857
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/GM326
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Dimensions Publication ID
1078547184
0 references
PMC publication ID
3446277
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PubMed publication ID
22494857
1 reference
stated in
Europe PubMed Central
PMC publication ID
3446277
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22494857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
ResearchGate publication ID
223976174
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