(Q102075636)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

title

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

Jair Machado Espindola-Netto

18 November 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Lilian S Gomez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Amrutesh S Puranik

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Guillermo Agorrody

11

1 reference

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18 November 2020

Bennett G Childs

15

1 reference

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18 November 2020

Melanie R McReynolds

22

1 reference

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18 November 2020

Connor Jankowski

23

1 reference

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18 November 2020

Tamar Tchkonia

24

1 reference

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18 November 2020

James L. Kirkland

25

1 reference

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18 November 2020

Joshua D Rabinowitz

30

1 reference

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18 November 2020

Joseph A. Baur

31

1 reference

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18 November 2020

Eduardo N. Chini

32

1 reference

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18 November 2020

27

Jan M van Deursen

1 reference

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18 November 2020

28

Darren J Baker

1 reference

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18 November 2020

author name string

Claudia C S Chini

1

1 reference

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18 November 2020

Gina M Warner

3

1 reference

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18 November 2020

Sonu Kashyap

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Guilherme C de Oliveira

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Kelly A Hogan

8

1 reference

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18 November 2020

Mariana G Tarragó

9

1 reference

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18 November 2020

Katie L Thompson

12

1 reference

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18 November 2020

Kevin Dang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Starlynn Clarke

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Karina S Kanamori

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Micaela A Witte

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Paola Vidal

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Anna L Kirkland

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Marco De Cecco

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Karthikeyani Chellappa

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

John M Sedivy

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

Wim van Schooten

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

publication date

16 November 2020

1 reference

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18 November 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

18 November 2020

page(s)

1284-1304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33199925%20AND%20SRC:MED&resulttype=core&format=json

The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases

18 November 2020

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Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

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Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice

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7 January 2021

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

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7 January 2021

Whole Chromosome Instability induces senescence and promotes SASP.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD decline

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7 January 2021

Ectocellular CD38-catalyzed synthesis and intracellular Ca2+-signalling activity of cyclic ADP-ribose in T-lymphocytes are not functionally related

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7 January 2021

NAD⁺-Metabolizing Ectoenzymes in Remodeling Tumor-Host Interactions: The Human Myeloma Model

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7 January 2021

Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma

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7 January 2021

CD38 antibodies in multiple myeloma: back to the future.

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7 January 2021

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor

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7 January 2021

CD38 is methylated in prostate cancer and regulates extracellular NAD

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7 January 2021

Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

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7 January 2021

Regulation of intracellular levels of NAD: a novel role for CD38.

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7 January 2021

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7 January 2021

Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.

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7 January 2021

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7 January 2021

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

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7 January 2021

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7 January 2021

Novel Markers to Delineate Murine M1 and M2 Macrophages

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38

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7 January 2021

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7 January 2021

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

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7 January 2021

A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157

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7 January 2021

Lipopolysaccharide activates ERK-PARP-1-RelA pathway and promotes nuclear factor-κB transcription in murine macrophages.

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7 January 2021

Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.

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7 January 2021

Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue

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7 January 2021

Lymphoid neogenesis and immune infiltration in aged liver

1 reference

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7 January 2021

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

1 reference

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7 January 2021

Elevated muscle TLR4 expression and metabolic endotoxemia in human aging

1 reference

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7 January 2021

Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice

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7 January 2021

CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells

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7 January 2021

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

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7 January 2021

Modulation of mammalian life span by the short isoform of p53.

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7 January 2021

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

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7 January 2021

Next generation immunotherapeutics--honing the magic bullet

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7 January 2021

Naturally occurring antibodies devoid of light chains

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7 January 2021

Camelid and shark single domain antibodies: structural features and therapeutic potential

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7 January 2021

Engineered antibody fragments and the rise of single domains

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7 January 2021

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

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7 January 2021

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

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7 January 2021

Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential.

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7 January 2021

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.

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7 January 2021

High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region

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7 January 2021

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

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7 January 2021

Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography

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7 January 2021

Aging, depot origin, and preadipocyte gene expression

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7 January 2021

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

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7 January 2021

10.1038/S42255-020-00298-Z

Identifiers

DOI

1 reference

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18 November 2020

1 reference