(Q89877356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

review article

1 reference

title

Age-related NAD+ decline (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

author name string

Melanie R McReynolds

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Karthikeyani Chellappa

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Joseph A Baur

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

publication date

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

published in

Experimental Gerontology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

volume

134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

page(s)

110888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32097708%20AND%20SRC:MED&resulttype=core&format=json

Rat liver cytosolic malate dehydrogenase: purification, kinetic properties, role in control of free cytosolic NADH concentration. Analysis of control of ethanol metabolism using computer simulation.

9 April 2020

cites work

1 reference

12 December 2020

[Kinetic and regulatory properties of alpha-ketoglutarate dehydrogenase complex from bovine adrenals].

1 reference

12 December 2020

Connexin 43 hemi channels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells

1 reference

12 December 2020

CD38 expression and functional activities are up-regulated by IFN-gamma on human monocytes and monocytic cell lines

1 reference

12 December 2020

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.

1 reference

12 December 2020

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

1 reference

12 December 2020

Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

1 reference

12 December 2020

Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids

1 reference

12 December 2020

NAD+ metabolism in health and disease

1 reference

12 December 2020

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

12 December 2020

Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress

1 reference

12 December 2020

Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle

1 reference

12 December 2020

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction

1 reference

12 December 2020

Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool

1 reference

12 December 2020

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

1 reference

12 December 2020

1 reference

12 December 2020

Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma

1 reference

12 December 2020

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

1 reference

12 December 2020

CD38: a NAADP degrading enzyme

1 reference

12 December 2020

The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+

1 reference

12 December 2020

Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase

1 reference

12 December 2020

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

1 reference

12 December 2020

Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases

1 reference

12 December 2020

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

1 reference

12 December 2020

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

1 reference

12 December 2020

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

1 reference

12 December 2020

Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid.

1 reference

12 December 2020

Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe.

1 reference

12 December 2020

Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging

1 reference

12 December 2020

Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction.

1 reference

12 December 2020

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

1 reference

12 December 2020

Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism

1 reference

12 December 2020

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

1 reference

12 December 2020

Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage

1 reference

12 December 2020

In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

1 reference

12 December 2020

SARM1 activation triggers axon degeneration locally via NAD⁺ destruction

1 reference

12 December 2020

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice

1 reference

12 December 2020

CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis.

1 reference

12 December 2020

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

1 reference

12 December 2020

Disruption of NAD(+) binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions

1 reference

12 December 2020

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

1 reference

12 December 2020

Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing.

1 reference

12 December 2020

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

1 reference

12 December 2020

Biosensor reveals multiple sources for mitochondrial NAD⁺.

1 reference

12 December 2020

NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice.

1 reference

12 December 2020

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

1 reference

12 December 2020

SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation

1 reference

12 December 2020

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

1 reference

12 December 2020

Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration.

1 reference

12 December 2020

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

1 reference

12 December 2020

Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Sirt1.

1 reference

12 December 2020

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

1 reference

12 December 2020

Nicotinamide Mononucleotide, an NAD+ Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1-Dependent Manner

1 reference

12 December 2020

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase

1 reference

12 December 2020

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.

1 reference

12 December 2020

A conserved NAD+ binding pocket that regulates protein-protein interactions during aging

1 reference

12 December 2020

Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging.

1 reference

12 December 2020

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

1 reference

12 December 2020

Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy

1 reference

12 December 2020

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.

1 reference

12 December 2020

Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.

1 reference

12 December 2020

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.

1 reference

12 December 2020

Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice

1 reference

12 December 2020

Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice.

1 reference

12 December 2020

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.

1 reference

12 December 2020

NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity.

1 reference

12 December 2020

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults.

1 reference

12 December 2020

CD38 produces nicotinic acid adenosine dinucleotide phosphate in the lysosome.

1 reference

12 December 2020

Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.

1 reference

12 December 2020

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline

1 reference

12 December 2020

CD38-cADPR-SERCA Signaling Axis Determines Skeletal Muscle Contractile Force in Response to β-Adrenergic Stimulation

1 reference

12 December 2020

Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis.

1 reference

12 December 2020

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides.

1 reference

12 December 2020

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria.

1 reference

12 December 2020

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

1 reference

12 December 2020

Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence

1 reference

12 December 2020

Dysregulation of NAD+ Metabolism Induces a Schwann Cell Dedifferentiation Program.

1 reference

12 December 2020

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

1 reference

12 December 2020

Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

1 reference

12 December 2020

CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions

1 reference

12 December 2020

Inflammaging: a new immune-metabolic viewpoint for age-related diseases

1 reference

12 December 2020

The Plasma NAD Metabolome Is Dysregulated in "Normal" Aging

1 reference

12 December 2020

Exogenous nicotinamide adenine dinucleotide regulates energy metabolism via hypothalamic connexin 43

1 reference

12 December 2020

Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock

1 reference

12 December 2020

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

1 reference

12 December 2020

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

1 reference

12 December 2020

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice

1 reference

12 December 2020

NMNAT2-mediated NAD+ generation is essential for quality control of aged oocytes

1 reference

12 December 2020

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD decline

1 reference

12 December 2020

Optical Redox Imaging of Fixed Unstained Muscle Slides Reveals Useful Biological Information.

1 reference

12 December 2020

Slc12a8 is a nicotinamide mononucleotide transporter

1 reference

12 December 2020

Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice

1 reference

12 December 2020

Aerobic and resistance exercise training reverses age-dependent decline in NAD+ salvage capacity in human skeletal muscle

1 reference

12 December 2020

Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

1 reference

12 December 2020

Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

1 reference

12 December 2020

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

1 reference

12 December 2020

Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice

1 reference

12 December 2020

Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program

1 reference

12 December 2020

Single-Voxel 1 H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD+ ) in humans at 7T using a 32-channel volume coil

1 reference

12 December 2020

Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria

1 reference

12 December 2020

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

1 reference

12 December 2020

Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men

1 reference

12 December 2020

Two-Photon Autofluorescence Imaging of Fixed Tissues: Feasibility and Potential Values for Biomedical Applications

1 reference

12 December 2020

Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus

1 reference

12 December 2020