(Q107112050)

1

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Virginie Girault

2

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Vincent Grass

3

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Ozge Karayel

4

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Valter Bergant

5

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Christian Urban

6

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Darya A. Haas

7

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Yiqi Huang

8

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Lila Oubraham

9

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Anqi Wang

10

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M. Sabri Hamad

11

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Antonio Piras

12

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Fynn M. Hansen

13

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Maria C. Tanzer

14

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Igor Paron

15

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Luca Zinzula

16

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Thomas Engleitner

17

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Maria Reinecke

18

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Teresa M. Lavacca

19

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Rosina Ehmann

20

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Roman Wölfel

21

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Jörg Jores

22

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Bernhard Kuster

23

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Roland Rad

25

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John Ziebuhr

26

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Volker Thiel

27

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Pietro Scaturro

28

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Matthias Mann

29

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Andreas Pichlmair

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

30

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publication date

12 April 2021

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published in

Nature

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cites work

1 reference

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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

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Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

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Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection

5 June 2021

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A SARS-CoV-2 – host proximity interactome

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Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms

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Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication

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SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

5 June 2021

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Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

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Virus-host interactome and proteomic survey of PBMCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

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Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

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Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling

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ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β

5 June 2021

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TGF-beta is a critical mediator of acute lung injury

5 June 2021

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Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

5 June 2021

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Abnormal pulmonary function in COVID-19 patients at time of hospital discharge

5 June 2021

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Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

5 June 2021

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SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome

5 June 2021

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Statin therapy in COVID-19 infection

5 June 2021

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Cholesterol in Relation to COVID-19: Should We Care about It?

5 June 2021

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Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

5 June 2021

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From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses

5 June 2021

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The Contribution of EDF1 to PPARγ Transcriptional Activation in VEGF-Treated Human Endothelial Cells

5 June 2021

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Endothelial Dysfunction in COVID-19: Lessons Learned from Coronaviruses

5 June 2021

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Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells

5 June 2021

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PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.

5 June 2021

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Surface vimentin is critical for the cell entry of SARS-CoV.

5 June 2021

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Vimentin regulates activation of the NLRP3 inflammasome.

5 June 2021

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Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral Infections

5 June 2021

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High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2

5 June 2021

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Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA

5 June 2021

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Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway

5 June 2021

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Hierarchical HotNet: identifying hierarchies of altered subnetworks

5 June 2021

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Coronavirus NSP6 restricts autophagosome expansion

5 June 2021

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Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Molecular interactions leading to lipoprotein retention and the initiation of atherosclerosis

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

5 June 2021

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Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

5 June 2021

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Antiviral activities of type I interferons to SARS-CoV-2 infection

5 June 2021

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Clinical development of targeted and immune based anti-cancer therapies

5 June 2021

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Janus kinase inhibitors in autoimmune diseases

5 June 2021

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The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer

5 June 2021

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ACE/ACE2 ratio and MMP-9 activity as potential biomarkers in tuberculous pleural effusions

5 June 2021

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Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure

5 June 2021

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Role of MMP2 and MMP9 in TRPV4-induced lung injury

5 June 2021

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Single-cell landscape of immunological responses in patients with COVID-19

5 June 2021

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Genomewide Association Study of Severe Covid-19 with Respiratory Failure

5 June 2021

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A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape

5 June 2021

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An orthogonal proteomic survey uncovers novel Zika virus host factors

5 June 2021

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

5 June 2021

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The alternative cap-binding complex is required for antiviral defense in vivo

5 June 2021

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Enzymatic synthesis and purification of a defined RIG-I ligand

5 June 2021

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Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

5 June 2021

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Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Large-scale identification of ubiquitination sites by mass spectrometry

5 June 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-021-03493-4

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

5 June 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-021-03493-4

Stan: A Probabilistic Programming Language

5 June 2021

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The Horseshoe+ Estimator of Ultra-Sparse Signals

5 June 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-021-03493-4

Peptide-level Robust Ridge Regression Improves Estimation, Sensitivity, and Specificity in Data-dependent Quantitative Label-free Shotgun Proteomics

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Cytoscape: a software environment for integrated models of biomolecular interaction networks

5 June 2021

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limma powers differential expression analyses for RNA-sequencing and microarray studies

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

5 June 2021

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Complex Portal 2018: extended content and enhanced visualization tools for macromolecular complexes

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

CORUM: the comprehensive resource of mammalian protein complexes-2019

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

The Perseus computational platform for comprehensive analysis of (prote)omics data

5 June 2021

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ChEA3: transcription factor enrichment analysis by orthogonal omics integration

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

UCSF Chimera--a visualization system for exploratory research and analysis

5 June 2021

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PyTMs: a useful PyMOL plugin for modeling common post-translational modifications

5 June 2021

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Bioinformatics Tools and Resources for Analyzing Protein Structures.

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

PBEQ-Solver for online visualization of electrostatic potential of biomolecules

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

The interferon antagonist ML protein of thogoto virus targets general transcription factor IIB.

5 June 2021

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Rapid and simple detection of IFN-neutralizing antibodies in chronic hepatitis C non-responsive to IFN-α

5 June 2021

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The PRIDE database and related tools and resources in 2019: improving support for quantification data

5 June 2021

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The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases

5 June 2021

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https://api.crossref.org/works/10.1038/S41586-021-03493-4

The Role of Metalloproteinases in Corona Virus Infection

5 June 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-021-03493-4

Modulating the transcriptional landscape of SARS-CoV-2 as an effective method for developing antiviral compounds

5 June 2021

1 reference

https://api.crossref.org/works/10.1038/S41586-021-03493-4