(Q99730760)

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SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

scientific article published on 18 September 2020

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29 September 2020

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response (English)

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29 September 2020

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Darrell N Kotton

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Darrell N Kotton

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29 September 2020

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Jessie Huang

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29 September 2020

Adam J Hume

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29 September 2020

Kristine M Abo

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Rhiannon B Werder

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29 September 2020

Carlos Villacorta-Martin

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Konstantinos-Dionysios Alysandratos

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Mary Lou Beermann

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29 September 2020

Chantelle Simone-Roach

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29 September 2020

Jonathan Lindstrom-Vautrin

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Judith Olejnik

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Ellen L Suder

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29 September 2020

Esther Bullitt

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29 September 2020

Anne Hinds

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29 September 2020

Arjun Sharma

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29 September 2020

Markus Bosmann

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29 September 2020

Ruobing Wang

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29 September 2020

Finn Hawkins

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29 September 2020

Eric J Burks

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29 September 2020

Mohsan Saeed

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29 September 2020

Andrew A Wilson

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29 September 2020

Elke Mühlberger

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publication date

18 September 2020

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29 September 2020

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29 September 2020

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Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

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1 reference

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1 reference

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1 reference

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1 reference

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Type 2 alveolar cells are stem cells in adult lung.

1 reference

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1 reference

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STAR: ultrafast universal RNA-seq aligner

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7500949

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1 reference

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1 March 2021

Identifiers

10.1016/J.STEM.2020.09.013

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29 September 2020

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29 September 2020

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