(Q116166980)

1

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Nicole D Wagner

2

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Angela J Zou

3

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Srirupa Chatterjee

4

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Dominika Borek

5

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Aidan R Cole

6

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Preston J Kim

7

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Christopher F Basler

8

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Zbyszek Otwinowski

9

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Michael L Gross

10

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Gaya K Amarasinghe

11

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Daisy W Leung

Proceedings of the National Academy of Sciences of the United States of America

12

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language of work or name

English

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publication date

9 March 2021

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published in

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volume

118

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issue

10

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cites work

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Molecular replacement with MOLREP

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

The Buccaneer software for automated model building. 1. Tracing protein chains

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infection

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

How RIG-I like receptors activate MAVS.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus nonstructural proteins decrease levels of multiple members of the cellular interferon pathways

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Identification of patterns in diffraction intensities affected by radiation exposure

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Refinement of macromolecular structures by the maximum-likelihood method

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growth

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Cytosolic sensing of viruses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Macromolecular TLS refinement in REFMAC at moderate resolutions

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Dali server: conservation mapping in 3D

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

VISA is an adapter protein required for virus-triggered IFN-beta signaling

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

RNA recognition and signal transduction by RIG-I-like receptors

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Identification of Respiratory Syncytial Virus Nonstructural Protein 2 Residues Essential for Exploitation of the Host Ubiquitin System and Inhibition of Innate Immune Responses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Viral and host factors in human respiratory syncytial virus pathogenesis

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

RIGorous detection: exposing virus through RNA sensing.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

RIG-I-like receptors: cytoplasmic sensors for non-self RNA.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Multiple functional domains and complexes of the two nonstructural proteins of human respiratory syncytial virus contribute to interferon suppression and cellular location

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Nonstructural protein-1 of respiratory syncytial virus regulates HOX gene expression through interacting with histone

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Comment on Houde, D; Berkowitz, S. A; Engen, J. R, The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies. J. Pharm. Sci. 2011, 100, 2071-2086

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Human Respiratory Syncytial Virus NS 1 Targets TRIM25 to Suppress RIG-I Ubiquitination and Subsequent RIG-I-Mediated Antiviral Signaling

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

RIG-I-like receptors: their regulation and roles in RNA sensing

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

RNA binding activates RIG-I by releasing an autorepressed signaling domain

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Human metapneumovirus glycoprotein G inhibits innate immune responses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural Insights into RNA Recognition by RIG-I

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Recent developments in classical density modification

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Diffraction data analysis in the presence of radiation damage

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

The Ebola virus VP35 protein functions as a type I IFN antagonist.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Coot: model-building tools for molecular graphics

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Efficient anisotropic refinement of macromolecular structures using FFT

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

The interactome of the human respiratory syncytial virus NS1 protein highlights multiple effects on host cell biology

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Evaluation of recombinant respiratory syncytial virus gene deletion mutants in African green monkeys for their potential as live attenuated vaccine candidates

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Structural insights into RNA recognition and activation of RIG-I-like receptors

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Viral evasion of intracellular DNA and RNA sensing

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering particles

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Gene expression of nucleic acid-sensing pattern recognition receptors in children hospitalized for respiratory syncytial virus-associated acute bronchiolitis

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus non-structural protein 1 facilitates virus replication through miR-29a-mediated inhibition of interferon-α receptor

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Viral degradasome hijacks mitochondria to suppress innate immunity

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Identification of the respiratory syncytial virus proteins required for formation and passage of helper-dependent infectious particles.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Handling ligands with Coot

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Processing of X-ray diffraction data collected in oscillation mode

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Multiparametric scaling of diffraction intensities

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory Syncytial Virus: Infection, Detection, and New Options for Prevention and Treatment

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Respiratory syncytial virus-mediated NF-kappa B p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKK beta

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

ICTV Virus Taxonomy Profile: Pneumoviridae

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Measurement errors and their consequences in protein crystallography

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity

11 January 2023

1 reference

https://api.crossref.org/works/10.1073/PNAS.2020587118