(Q90590779)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

review article

1 reference

title

RIG-I-like receptors: their regulation and roles in RNA sensing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

Michaela Gack

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

publication date

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

14 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

Virus interference. I. The interferon

14 April 2020

cites work

1 reference

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7 January 2021

Type I interferons in infectious disease

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7 January 2021

Intrinsic antiviral immunity

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7 January 2021

Interferons and the Immunogenic Effects of Cancer Therapy

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7 January 2021

STING: infection, inflammation and cancer

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7 January 2021

Type I interferons in anticancer immunity

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7 January 2021

Aicardi-Goutières syndrome and the type I interferonopathies

1 reference

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7 January 2021

Do Type I Interferons Link Systemic Autoimmunities and Metabolic Syndrome in a Pathogenetic Continuum?

1 reference

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7 January 2021

Interferons, interferon-like cytokines, and their receptors

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7 January 2021

The JAK-STAT pathway at twenty

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7 January 2021

The molecular basis for functional plasticity in type I interferon signaling

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7 January 2021

Nucleic Acid Immunity

1 reference

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7 January 2021

Cytosolic sensing of viruses

1 reference

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7 January 2021

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

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7 January 2021

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

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7 January 2021

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural Insights into RNA Recognition by RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

5'-Triphosphate RNA is the ligand for RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I Uses an ATPase-Powered Translocation-Throttling Mechanism for Kinetic Proofreading of RNAs and Oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

How RIG-I like receptors activate MAVS.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I Selectively Discriminates against 5'-Monophosphate RNA

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mini viral RNAs act as innate immune agonists during influenza virus infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I Recognizes the 5' Region of Dengue and Zika Virus Genomes

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Targeting the viral Achilles' heel: recognition of 5'-triphosphate RNA in innate anti-viral defence

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Cellular functions of vaults and their involvement in multidrug resistance.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Small self-RNA generated by RNase L amplifies antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Aicardi-Goutières syndrome is caused by IFIH1 mutations.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Association of the IFIH1-GCA-KCNH7 chromosomal region with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Human Respiratory Syncytial Virus NS 1 Targets TRIM25 to Suppress RIG-I Ubiquitination and Subsequent RIG-I-Mediated Antiviral Signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Viral evasion of intracellular DNA and RNA sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM25 in the Regulation of the Antiviral Innate Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Hepatitis C Virus Infection Is Inhibited by a Noncanonical Antiviral Signaling Pathway Targeted by NS3-NS4A

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ubiquitination in the antiviral immune response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Stratified ubiquitination of RIG-I creates robust immune response and induces selective gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

USP4 positively regulates RIG-I-mediated antiviral response through deubiquitination and stabilization of RIG-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Phosphorylation-mediated negative regulation of RIG-I antiviral activity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Phosphorylation of RIG-I by casein kinase II inhibits its antiviral response.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Conventional protein kinase C-α (PKC-α) and PKC-β negatively regulate RIG-I antiviral signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

DHX15 Is a Coreceptor for RLR Signaling That Promotes Antiviral Defense Against RNA Virus Infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM25 binds RNA to modulate cellular anti-viral defense

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Epigenetic regulation of the innate immune response to infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Downregulation of microRNA miR-526a by enterovirus inhibits RIG-I-dependent innate immune response.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A Human Long Non-coding RNA LncATV Promotes Virus Replication Through Restricting RIG-I-Mediated Innate Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Immunobiology of Long Noncoding RNAs.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Long Non-Coding RNA-Mediated Regulation of the Interferon Response: A New Perspective on a Familiar Theme

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Autophagy in infection, inflammation, and immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

LRRC25 inhibits type I IFN signaling by targeting ISG15-associated RIG-I for autophagic degradation.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The Atg5 Atg12 conjugate associates with innate antiviral immune responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MAVS maintains mitochondrial homeostasis via autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I activation induces the release of extracellular vesicles with antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity toward autologous melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I activation is critical for responsiveness to checkpoint blockade

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Sensing Self and Foreign Circular RNAs by Intron Identity.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

N6-Methyladenosine Modification Controls Circular RNA Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM Proteins and Their Roles in Antiviral Host Defenses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM family proteins and their emerging roles in innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ubiquitin in the activation and attenuation of innate antiviral immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Human TRIM gene expression in response to interferons

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM23 mediates virus-induced autophagy via activation of TBK1.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The TRIMendous Role of TRIMs in Virus-Host Interactions

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Nasopharyngeal carcinoma progression is mediated by EBER-triggered inflammation via the RIG-I pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus in primary human macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Activation of MDA5 requires higher-order RNA structures generated during virus infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Adenovirus virus-associated RNAs induce type I interferon expression through a RIG-I-mediated pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 plays a critical role in interferon response during hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

Melanoma differentiation-associated gene 5 senses hepatitis B virus and activates innate immune signaling to suppress virus replication

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus

1 reference

https://api.crossref.org/works/10.1038%2FS41577-020-0288-3

7 January 2021

REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I

1 reference

12 December 2020

Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

1 reference

12 December 2020

Sequencing-based approach identified three new susceptibility loci for psoriasis

1 reference

12 December 2020

Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells

1 reference

12 December 2020

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction

1 reference

12 December 2020

Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform

1 reference

12 December 2020

The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling

1 reference

12 December 2020

The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling.

1 reference

12 December 2020

The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells

1 reference

12 December 2020

Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

1 reference

12 December 2020

Nuclear-resident RIG-I senses viral replication inducing antiviral immunity

1 reference

12 December 2020

RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection

1 reference

12 December 2020

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

1 reference

12 December 2020

The 14-3-3η chaperone protein promotes antiviral innate immunity via facilitating MDA5 oligomerization and intracellular redistribution

1 reference

12 December 2020

RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection

1 reference

12 December 2020

10.1038/S41577-020-0288-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32203325%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 April 2020

1125625986

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference