(Q59352927)

Interferon induced with helicase C domain 1

15 December 2019

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28 September 2019

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3 May 2021

periodic fever syndrome

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30201512

innate immune response

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30201512

viral RNA

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Natalia Guimaraes Sampaio

3

Jan Rehwinkel

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object named as

Natalia G Sampaio

series ordinal

2

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author name string

Antonio Gregorio Dias Junior

series ordinal

1

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language of work or name

English

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publication date

7 September 2018

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1 January 2019

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28 September 2019

15 December 2019

3 May 2021

25 May 2022

Trends in Microbiology

2 references

3 May 2021

25 May 2022

27

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issue

1

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page(s)

75-85

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copyright license

Creative Commons Attribution 4.0 International

2 references

Europe PubMed Central

28 September 2019

Europe PubMed Central

Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts

15 December 2019

cites work

1 reference

12 December 2020

Enzymic synthesis of polynucleotides. I. Polynucleotide phosphorylase of Azotobacter vinelandii. 1956.

1 reference

12 December 2020

The specificity of interferon induction in chick embryo cells by helical RNA.

1 reference

12 December 2020

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

1 reference

12 December 2020

Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

1 reference

12 December 2020

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

12 December 2020

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

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12 December 2020

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

1 reference

12 December 2020

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

1 reference

12 December 2020

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 reference

12 December 2020

5'-Triphosphate RNA is the ligand for RIG-I

1 reference

12 December 2020

Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

1 reference

12 December 2020

Association of the IFIH1-GCA-KCNH7 chromosomal region with rheumatoid arthritis

1 reference

12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 reference

12 December 2020

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

1 reference

12 December 2020

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

1 reference

12 December 2020

Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1.

1 reference

12 December 2020

Approaching the asymptote: 20 years later

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12 December 2020

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

1 reference

12 December 2020

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

1 reference

12 December 2020

Activation of MDA5 requires higher-order RNA structures generated during virus infection

1 reference

12 December 2020

Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses.

1 reference

12 December 2020

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

1 reference

12 December 2020

Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells

1 reference

12 December 2020

MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.

1 reference

12 December 2020

Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo

1 reference

12 December 2020

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

12 December 2020

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

1 reference

12 December 2020

Peroxisomes are signaling platforms for antiviral innate immunity

1 reference

12 December 2020

Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis

1 reference

12 December 2020

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

1 reference

12 December 2020

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

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12 December 2020

Reduced expression of IFIH1 is protective for type 1 diabetes

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12 December 2020

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

1 reference

12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

1 reference

12 December 2020

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

1 reference

12 December 2020

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

1 reference

12 December 2020

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease

1 reference

12 December 2020

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

1 reference

12 December 2020

Intrinsic antiviral immunity

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12 December 2020

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

1 reference

12 December 2020

Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses

1 reference

12 December 2020

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

1 reference

12 December 2020

Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments

1 reference

12 December 2020

MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells.

1 reference

12 December 2020

Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo

1 reference

12 December 2020

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

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12 December 2020

Cytosolic sensing of viruses

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12 December 2020

Melanoma differentiation-associated gene 5 senses hepatitis B virus and activates innate immune signaling to suppress virus replication

1 reference

12 December 2020

RADAR: a rigorously annotated database of A-to-I RNA editing

1 reference

12 December 2020

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.

1 reference

12 December 2020

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

1 reference

12 December 2020

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

1 reference

12 December 2020

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

1 reference

12 December 2020

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells

1 reference

12 December 2020

The enemy within: endogenous retroelements and autoimmune disease

1 reference

12 December 2020

TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner.

1 reference

12 December 2020

MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction

1 reference

12 December 2020

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

1 reference

12 December 2020

Aicardi-Goutières syndrome is caused by IFIH1 mutations.

1 reference

12 December 2020

Sequencing-based approach identified three new susceptibility loci for psoriasis

1 reference

12 December 2020

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

1 reference

12 December 2020

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly

1 reference

12 December 2020

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

1 reference

12 December 2020

MDA5 plays a critical role in interferon response during hepatitis C virus infection

1 reference

12 December 2020

Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes

1 reference

12 December 2020

Type I interferons in infectious disease

1 reference

12 December 2020

A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome

1 reference

12 December 2020

Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways

1 reference

12 December 2020

ATP-dependent effector-like functions of RIG-I-like receptors

1 reference

12 December 2020

Aicardi-Goutières syndrome and the type I interferonopathies

1 reference

12 December 2020

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

1 reference

12 December 2020

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome

1 reference

12 December 2020

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

1 reference

12 December 2020

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

1 reference

12 December 2020

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

1 reference

12 December 2020

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

1 reference

12 December 2020

MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.

1 reference

12 December 2020

Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity

1 reference

12 December 2020

Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode

1 reference

12 December 2020

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.

1 reference

12 December 2020

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus

1 reference

12 December 2020

Activation of the MDA-5-IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity

1 reference

12 December 2020

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

1 reference

12 December 2020

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction

1 reference

12 December 2020

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

1 reference

12 December 2020

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

1 reference

12 December 2020

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.

1 reference

12 December 2020

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

1 reference

12 December 2020

ALUternative Regulation for Gene Expression

1 reference

12 December 2020

Nucleic Acid Immunity

1 reference

12 December 2020

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.

1 reference

12 December 2020

The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.

1 reference

12 December 2020

Recurrent rhinovirus infections in a child with inherited MDA5 deficiency.

1 reference

12 December 2020

Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection

1 reference

12 December 2020

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations.

1 reference

12 December 2020

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

1 reference

12 December 2020

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

1 reference

12 December 2020

Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.

1 reference

12 December 2020

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

1 reference

12 December 2020

The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy

1 reference

12 December 2020

Recurrent and Prolonged Infections in a Child with a Homozygous IFIH1 Nonsense Mutation

1 reference

12 December 2020

Dynamic landscape and regulation of RNA editing in mammals.

1 reference

12 December 2020

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

1 reference

12 December 2020

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

1 reference

12 December 2020

The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells

1 reference

12 December 2020

Advances in CLIP Technologies for Studies of Protein-RNA Interactions.

1 reference

12 December 2020

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.

1 reference

12 December 2020

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation.

1 reference

12 December 2020

DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity.

1 reference

12 December 2020

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

1 reference

12 December 2020

LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways

1 reference

12 December 2020

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling.

1 reference

12 December 2020

A-to-I RNA editing — immune protector and transcriptome diversifier

1 reference

12 December 2020

Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response.

1 reference

12 December 2020

Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

1 reference

12 December 2020

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

1 reference

12 December 2020

10.1016/J.TIM.2018.08.007

Identifiers

DOI

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PMC publication ID

6319154

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