(Q19856779)

Gene Ontology release 2019-11-16

mitomycin C catabolic process

subject has role

reactant

1 reference

Gene Ontology release 2019-11-16

mitomycin C biosynthetic process

subject has role

product

1 reference

Gene Ontology release 2019-11-16

has use

medication

0 references

chemical structure

Mitomycin 2.svg
397 × 362; 31 KB

1 reference

imported from Wikimedia project

German Wikipedia

mass

334.12772 dalton

1 reference

mitomycin C (English)

3 October 2016

1 reference

C₁₅H₁₈N₄O₅

1 reference

mitomycin C (English)

19 November 2016

canonical SMILES

CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N

1 reference

mitomycin C (English)

19 November 2016

isomeric SMILES

CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N

1 reference

mitomycin C (English)

19 November 2016

1 reference

14 February 2018

Streptomyces lavendulae

2 references

Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564

Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae

Streptomyces purpurascens

1 reference

Production of mitomycin C and porfiromycin by Streptomyces species

Streptomyces violaceus

1 reference

Production of mitomycin C and porfiromycin by Streptomyces species

Streptomyces

1 reference

The Structures of Mitomycins A, B and C and Porfiromycin--Part I

Streptomyces caespitosus

2 references

New mitomycin analogs produced by directed biosynthesis

Effect of sodium arsenite on the biosynthesis of mitomycins by Streptomyces caespitosus and mode of action of mitomycin C on Bacillus subtilis NRRL B-543

Scoparia dulcis

1 reference

Cytotoxic diterpenes from Scoparia dulcis

Cedrus deodara

1 reference

Tubulin inhibitors from an endophytic fungus isolated from Cedrus deodara

Micromonospora yangpuensis

1 reference

Yangpumicins F and G, Enediyne Congeners from Micromonospora yangpuensis DSM 45577

medical condition treated

1 reference

13 December 2016

large intestine cancer

1 reference

13 December 2016

1 reference

13 December 2016

2 references

13 December 2016

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

vinblastine

side effect

bone marrow failure

1 reference

sourcing circumstances

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

vinblastine

side effect

embolism

1 reference

sourcing circumstances

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

legal status (medicine)

boxed warning

1 reference

reference URL

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

Australian pregnancy category D

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

2 references

5 March 2018

MeSH descriptor ID

D016685

DNA polymerase inhibitors

15 March 2018

2 references

5 March 2018

MeSH descriptor ID

D016685

antineoplastic antibiotics

15 March 2018

1 reference

MeSH descriptor ID

D016685

15 March 2018

cross-linking reagent

1 reference

California Proposition 65 list of chemicals

15 March 2018

1 reference

https://oehha.ca.gov/chemicals/mitomycin-c

18 March 2020

reference URL

1 reference

Identifiers

InChI

InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

1 reference

mitomycin C (English)

NWIBSHFKIJFRCO-WUDYKRTCSA-N

19 November 2016

InChIKey

2 references

mitomycin C (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

50-07-7

2 references

NWIBSHFKIJFRCO-WUDYKRTCSA-N

mitomycin (English)

19 November 2016

9 April 2021

https://commonchemistry.cas.org/detail?cas_rn=50-07-7

1 reference

Mitomycin (English)

19 November 2016

1 reference

mitomycin C (English)

19 November 2016

Reaxys registry number

3570056

1 reference

mitomycin C (English)

3 October 2016

ChEBI ID

27504

mapping relation type

1 reference

MITOMYCIN (English)

19 November 2016

1 reference

Hazardous Substances Data Bank

MITOMYCIN (English)

19 November 2016

1 reference

MassBank accession ID

MSBNK-Waters-WA000767

0 references

MSBNK-Waters-WA000768

0 references

MSBNK-Waters-WA000769

0 references

MSBNK-Waters-WA000770

0 references

MSBNK-Waters-WA000771

0 references

0 references

0 references

1 reference

28 October 2019

MITOMYCIN C (English)

10 May 2021

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

200-008-6

1 reference

mitomycin (English)

ECHA Substance Infocard ID

19 November 2016

100.000.008

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Mitomycin (English)

CAS no.: 50-07-7 (English)

AICS Chemical ID (BEING DELETED)

386

0 references

Guide to Pharmacology Ligand ID

7089

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7089

mitomycin C (English)

19 November 2016

Mitomycin

1 reference

D03.633.100.473.412.249.350

14 March 2018

0 references

0 references

0 references

RxNorm ID

632

1 reference

mitomycin (English)

19 November 2016

1 reference

Mitomycin (English)

19 November 2016

1 reference

mitomycin C (English)

3 October 2016

1 reference

mitomycin (English)

MedlinePlus drug identifier

19 November 2016

0 references

1 reference

mitomycin (English)

19 November 2016

0 references

1 reference

1 reference

California Proposition 65 list of chemicals

mitomycin C (English)

3 October 2016

1 reference

https://oehha.ca.gov/chemicals/mitomycin-c

6 January 2020

reference URL

Google Knowledge Graph ID

/g/11bc7p_4hz

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0002475

1 reference

YSO-Wikidata mapping project

mitomycin (English)

19 November 2016

0 references

1 reference