(Q23923209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation (English)

2 references

12 July 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

NIOSH Health Effects Laboratory Division

29 February 2020

sponsor

object named as

HELD

1 reference

25 September 2023

1 reference

19 July 2017

1 reference

29 March 2020

1 reference

29 March 2020

non-small-cell lung carcinoma

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Todd A. Stueckle

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

George A O'Doherty

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Pithi Chanvorachote

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Varisa Pongrakhananon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Hua-Yu Leo Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Cerasela Zoica Dinu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

11 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

published in

Biochemical Pharmacology

2 references

8 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

88

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

23-35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

on focus list of Wikimedia project

29 February 2020

Wikimedia–NIOSH collaboration

0 references

2 references

2 February 2024

inferred from email address

cites work

Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells

2 references

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

19 March 2017

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

19 March 2017

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19 March 2017

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19 March 2017

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A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated Apoptosis

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Microenvironmental regulation of metastasis

7 April 2017

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Dissemination and growth of cancer cells in metastatic sites

7 April 2017

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Overexpression of Smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer A549 cells

7 April 2017

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The glycogen synthase kinase-3β/nuclear factor-kappa B pathway is involved in cinobufagin-induced apoptosis in cultured osteosarcoma cells

27 September 2017

1 reference

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Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell

27 September 2017

1 reference

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The sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors

27 September 2017

1 reference

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UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells

27 September 2017

1 reference

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Mcl-1; the molecular regulation of protein function

27 September 2017

1 reference

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Glycogen synthase kinase 3 beta: can it be a target for oral cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation

27 September 2017

1 reference

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Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis.

27 September 2017

1 reference

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Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex

27 September 2017

1 reference

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Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets

27 September 2017

1 reference

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Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation

27 September 2017

1 reference

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Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy

27 September 2017

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27 September 2017

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The de novo synthesis of oligosaccharides: application to the medicinal chemistry SAR-study of digitoxin

27 September 2017

1 reference

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Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells

27 September 2017

1 reference

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Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis

27 September 2017

1 reference

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The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours

27 September 2017

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27 September 2017

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Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

27 September 2017

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Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

27 September 2017

1 reference

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Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5.

27 September 2017

1 reference

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Oleandrin-mediated oxidative stress in human melanoma cells

27 September 2017

1 reference

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Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

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27 September 2017

1 reference

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Regulation of Bcl-2 proteins during anoikis and amorphosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Digitalis toxicity: mechanisms, diagnosis, and management

27 September 2017

1 reference

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Mcl-1 is required for melanoma cell resistance to anoikis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Human intestinal epithelial cell survival and anoikis. Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970117

Unraveling MCL-1 degradation

29 November 2018

1 reference

12 December 2020

P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation

1 reference

12 December 2020

Digitoxin is a potential anticancer agent for several types of cancer

1 reference

12 December 2020

Cardiac glycosides and breast cancer, revisited

1 reference

12 December 2020

Cardiac glycosides and breast cancer

1 reference

12 December 2020

Paradoxical angina after nitroglycerin--another variant

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.BCP.2013.10.027

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.BCP.2013.10.027

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24231508%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24231508

1 reference