(Q24294849)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

Transformation related protein 53

9 February 2020

main subject

1 reference

Transformed mouse 3T3 cell double minute 4

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Marsha Pellegrino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fabiola Moretti

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

S Giglio

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

F Mancini

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

G Di Conza

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

E Puxeddu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

A Sacchi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

A Pontecorvi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

9 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

5935-5945

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

9 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H(2)O(2)-induced oxidative stress in neonatal rat cardiac myocytes

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.324

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Human MDM2 isoforms translated differentially on constitutive versus p53-regulated transcripts have distinct functions in the p53/MDM2 and TSG101/MDM2 feedback control loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

p53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

DNA damage-induced MDMX degradation is mediated by MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

MDM4 (MDMX) and its Transcript Variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Mitochondrial MDM4 (MDMX): an unpredicted role in the p53-mediated intrinsic apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Mdm2-mediated ubiquitylation: p53 and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

MDM2 promotes ubiquitination and degradation of MDMX

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Induction of MDM2-P2 transcripts correlates with stabilized wild-type p53 in betel- and tobacco-related human oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

MDM2 and MDM4: p53 regulators as targets in anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Guarding the guardian: Mdmx plays important roles in setting p53 basal activity and determining biological responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

IFN regulatory factor 8 regulates MDM2 in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Abnormal expression of MDM-2 in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

Multiple murine double minute gene 2 (MDM2) proteins are induced by ultraviolet light

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.324

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.324

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20697359%20AND%20SRC:MED&resulttype=core&format=json