(Q28200748)

4

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Fabiola Moretti

7

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Francesca Gentiletti

1

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Francesca Mancini

2

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author name string

Francesca Gentiletti

1

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Marco D'Angelo

3

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Alfredo Pontecorvi

5

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Aart G Jochemsen

New de-ubiquitinating enzyme, ubiquitin C-terminal hydrolase 8, in chick skeletal muscle

6

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language of work or name

English

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publication date

31 January 2002

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published in

Oncogene

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volume

21

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issue

6

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page(s)

867-77

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Mapping of the p53 and mdm-2 interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Proteolytic cleavage of the mdm2 oncoprotein during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Constitutive mdmx expression during cell growth, differentiation, and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

MdmX protects p53 from Mdm2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Interpreting cDNA sequences: some insights from studies on translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

The G(2) checkpoint is maintained by redundant pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Activation of an MDM2-specific caspase by p53 in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

p53 associates with and targets Delta Np63 into a protein degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Differential responses of proliferating versus quiescent cells to adriamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Kinetics of p53 binding to promoter sites in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

MDM2 interacts with MDMX through their RING finger domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

Suicidal tendencies: apoptotic cell death by caspase family proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

mdm2 expression is induced by wild type p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

7 January 2021

Comparative study of the p53-mdm2 and p53-MDMX interfaces

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

7 January 2021

A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

7 January 2021

Multiple murine double minute gene 2 (MDM2) proteins are induced by ultraviolet light

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205137

7 January 2021