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The RAG1 N-terminal domain is an E3 ubiquitin ligase
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scholarly article
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title
The RAG1 N-terminal domain is an E3 ubiquitin ligase
(English)
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main subject
Ubiquitin like modifier activating enzyme 1
1 reference
stated in
GOA release 2020-03-11
Ubiquitin conjugating enzyme E2 C
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stated in
GOA release 2020-03-11
ubiquitin activating enzyme activity
1 reference
stated in
GOA release 2020-03-11
Recombination activating gene 2
1 reference
stated in
GOA release 2020-03-11
Recombination activating 1
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stated in
GOA release 2020-03-11
author name string
Vyacheslav Yurchenko
series ordinal
1
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Zhu Xue
series ordinal
2
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Moshe Sadofsky
series ordinal
3
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language of work or name
English
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publication date
1 March 2003
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published in
Genes & Development
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volume
17
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issue
5
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page(s)
581-5
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cites work
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
Histone ubiquitination: a tagging tail unfolds?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
Themes and variations on ubiquitylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
Expression and V(D)J recombination activity of mutated RAG-1 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
19 March 2017
RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
V(D)J recombination: RAG proteins, repair factors, and regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
The mechanism and regulation of chromosomal V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Assembly of the RAG1/RAG2 synaptic complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Functional organization of single and paired V(D)J cleavage complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
The RAG proteins in V(D)J recombination: more than just a nuclease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Analysis of regions of RAG-2 important for V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
Definition of a core region of RAG-2 that is functional in V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
27 September 2017
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=196008
retrieved
29 November 2018
Regions of RAG1 protein critical for V(D)J recombination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12629039
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A zinc-binding domain involved in the dimerization of RAG1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12629039
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The U box is a modified RING finger — a common domain in ubiquitination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12629039
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.1058103
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4496756
OpenCitations bibliographic resource ID
4496756
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4496756
PMC publication ID
196008
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4496756
PubMed publication ID
12629039
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4496756
ResearchGate publication ID
10863315
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