(Q24318857)

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RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-specific nucleotide exchange

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RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-specific nucleotide exchange (English)

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RasGEF domain family member 1B

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GOA release 2020-03-11

RasGEF domain family member 1A

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GOA release 2020-03-11

guanyl-nucleotide exchange factor activity

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GOA release 2020-03-11

Alfred Wittinghofer

4

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author name string

Elif Yaman

1

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Raphael Gasper

2

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Carolin Koerner

3

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Uygar H Tazebay

5

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language of work or name

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publication date

August 2009

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276

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16

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4607-16

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The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.

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Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors

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The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes

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Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins

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Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation

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Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins

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GEFs and GAPs: critical elements in the control of small G proteins

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Recognizing and defining true Ras binding domains I: biochemical analysis

1 reference

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Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach

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The role of the conserved switch II glutamate in guanine nucleotide exchange factor-mediated nucleotide exchange of GTP-binding proteins

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Expression of rasgef1b in zebrafish

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Structural and mechanistic insights into ras association domains of phospholipase C epsilon

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Rap2-JNK removes synaptic AMPA receptors during depotentiation

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Epac proteins: multi-purpose cAMP targets

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Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements

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Analysis of interaction between Ras and CDC25 guanine nucleotide exchange factor using yeast GAL4 two-hybrid system

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The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

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The structural basis of the activation of Ras by Sos

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Rap1 signalling: adhering to new models

1 reference

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Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

1 reference

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Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

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A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

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Ras oncogenes: split personalities

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Rap2 is required for Wnt/beta-catenin signaling pathway in Xenopus early development

1 reference

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Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

1 reference

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Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex

1 reference

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Mitogenic and oncogenic properties of the small G protein Rap1b

1 reference

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Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors

1 reference

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Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts

1 reference

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1 reference

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Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition

1 reference

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1 reference

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Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase

1 reference

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Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Small GTP-binding proteins

1 reference

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inferred from DOI database lookup

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10.1111/J.1742-4658.2009.07166.X

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