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Identification of the LEDGF/p75 binding site in HIV-1 integrase
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title
Identification of the LEDGF/p75 binding site in HIV-1 integrase
(English)
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author
Zeger Debyser
series ordinal
8
object named as
Zeger Debyser
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Marc De Maeyer
series ordinal
3
object named as
Marc De Maeyer
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Frauke Christ
series ordinal
9
object named as
Frauke Christ
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author name string
Katrien Busschots
series ordinal
1
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Arnout Voet
series ordinal
2
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Jean-Christophe Rain
series ordinal
4
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Stéphane Emiliani
series ordinal
5
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Richard Benarous
series ordinal
6
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Linda Desender
series ordinal
7
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language of work or name
English
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publication date
2 February 2007
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published in
Journal of Molecular Biology
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volume
365
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issue
5
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page(s)
1480-92
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cites work
Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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Cellular co-factors of HIV-1 integration
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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Molecular mechanisms in retrovirus DNA integration
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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HIV-1 infection requires a functional integrase NLS.
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis
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Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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The dead-end elimination theorem and its use in protein side-chain positioning
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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Comparative architecture of transposase and integrase complexes
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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A role for LEDGF/p75 in targeting HIV DNA integration
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
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reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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inferred from DOI database lookup
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
inferred from DOI database lookup
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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HIV integrase, a brief overview from chemistry to therapeutics
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Swiss-PDB Viewer (Deep View).
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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An improved PCR-mutagenesis strategy for two-site mutagenesis or sequence swapping between related genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
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High-level expression of active HIV-1 integrase from a synthetic gene in human cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for LEDGF/p75 in HIV integration
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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inferred from DOI database lookup
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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inferred from DOI database lookup
Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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inferred from DOI database lookup
Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
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Lys-34, dispensable for integrase catalysis, is required for preintegration complex function and human immunodeficiency virus type 1 replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
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Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus
1 reference
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https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
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Intracellular transport of human immunodeficiency virus type 1 integrase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
based on heuristic
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Human cell proteins and human immunodeficiency virus DNA integration
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094
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7 January 2021
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Identifiers
DOI
10.1016/J.JMB.2006.10.094
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2600267
Fatcat ID
release_j7zalgamrrarje2t5hhfbqrcxm
0 references
OpenCitations bibliographic resource ID
2600267
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2600267
PubMed publication ID
17137594
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2600267
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