(Q24337421)

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Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase

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scholarly article

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Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase (English)

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Elastase, neutrophil expressed

1 reference

GOA release 2020-03-11

NEDD4 binding protein 2 like 2

1 reference

GOA release 2020-03-11

Growth factor independent 1 transcriptional repressor

1 reference

GOA release 2020-03-11

NEDD4 binding protein 2-like 2

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

H. Leighton Grimes

8

object named as

H Leighton Grimes

author given names

H Leighton

author last names

Grimes

1 reference

PubMed publication ID

20 October 2023

author name string

Stephen J Salipante

1

author given names

Stephen J

author last names

Salipante

1 reference

PubMed publication ID

20 October 2023

Meghan E B Rojas

2

author given names

Meghan E B

author last names

Rojas

1 reference

PubMed publication ID

20 October 2023

Brice Korkmaz

3

author given names

Brice

author last names

Korkmaz

1 reference

PubMed publication ID

20 October 2023

Zhijun Duan

4

author given names

Zhijun

author last names

Duan

1 reference

PubMed publication ID

20 October 2023

Jeremy Wechsler

5

author given names

Jeremy

author last names

Wechsler

1 reference

PubMed publication ID

20 October 2023

Kathleen F Benson

6

author given names

Kathleen F

author last names

Benson

1 reference

PubMed publication ID

20 October 2023

Richard E Person

7

author given names

Richard E

author last names

Person

1 reference

PubMed publication ID

20 October 2023

Marshall S Horwitz

9

author given names

Marshall S

author last names

Horwitz

1 reference

PubMed publication ID

20 October 2023

language of work or name

0 references

publication date

August 2009

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Molecular and Cellular Biology

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29

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16

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4394-405

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A syndrome with congenital neutropenia and mutations in G6PC3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

19 March 2017

Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor

1 reference

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19 March 2017

Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5

1 reference

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19 March 2017

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

1 reference

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19 March 2017

Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon gene

1 reference

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19 March 2017

Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

19 March 2017

Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

19 March 2017

Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2

1 reference

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19 March 2017

Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination

1 reference

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Neutrophil extracellular traps kill bacteria

1 reference

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19 March 2017

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

19 March 2017

Mimicking cellular sorting improves prediction of subcellular localization

1 reference

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19 March 2017

Hereditary neutropenia: dogs explain human neutrophil elastase mutations

1 reference

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19 March 2017

Processing and targeting of granule proteins in human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

19 March 2017

Large-scale analysis of the human and mouse transcriptomes

1 reference

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7 April 2017

Novel cell death program leads to neutrophil extracellular traps

1 reference

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7 April 2017

Finding nuclear localization signals

1 reference

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Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

1 reference

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7 April 2017

Gfi1 integrates progenitor versus granulocytic transcriptional programming

1 reference

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27 September 2017

WHIM syndrome: congenital immune deficiency disease

1 reference

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The expanding role of arsenic in acute promyelocytic leukemia

1 reference

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27 September 2017

Genetic heterogeneity in severe congenital neutropenia: how many aberrant pathways can kill a neutrophil?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

Novel insights from adaptor protein 3 complex deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

Severe congenital neutropenia: new genes explain an old disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

Riding tandem: circadian clocks and the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

Neutrophil elastase in cyclic and severe congenital neutropenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

27 September 2017

5. Mechanisms of disordered granulopoiesis in congenital neutropenia

1 reference

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Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population

1 reference

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Transcriptional feedback oscillators: maybe, maybe not...

1 reference

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27 September 2017

Arsenic trioxide (AT) is a novel human neutrophil pro-apoptotic agent: effects of catalase on AT-induced apoptosis, degradation of cytoskeletal proteins and de novo protein synthesis

1 reference

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Automated prediction of domain boundaries in CASP6 targets using Ginzu and RosettaDOM.

1 reference

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ATP citrate lyase is an important component of cell growth and transformation

1 reference

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27 September 2017

Neutrophil elastase is important for PML-retinoic acid receptor alpha activities in early myeloid cells

1 reference

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Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place

1 reference

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Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

1 reference

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27 September 2017

Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice

1 reference

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Congenital neutropenia

1 reference

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27 September 2017

Targets of the transcriptional repressor oncoprotein Gfi-1

1 reference

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Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum

1 reference

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27 September 2017

Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis.

1 reference

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Changes in chromatin organization at the neutrophil elastase locus associated with myeloid cell differentiation

1 reference

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27 September 2017

Cyclical neutropenia and other periodic hematological disorders: a review of mechanisms and mathematical models.

1 reference

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27 September 2017

The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal

1 reference

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Role of chalone in granulopoiesis

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Cyclic hemopoiesis and feedback control

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27 September 2017

Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL.

1 reference

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Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

29 November 2018

Mutations in the ELA2 gene correlate with more severe expression of neutropenia: a study of 81 patients from the French Neutropenia Register.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

29 November 2018

Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

29 November 2018

Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

29 November 2018

Characterization of mutant neutrophil elastase in severe congenital neutropenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

29 November 2018

Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2725743

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Characterization and localization of the genes for mouse proteinase-3 (Prtn3) and neutrophil elastase (Ela2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

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inferred from PubMed ID database lookup

Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of TRF2 by radiation-induced apoptosis in HL60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of transcriptions in primary granule constituents during myeloid proliferation and differentiation in patients with severe congenital neutropenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of CAMAL-mediated alterations of normal and leukemic in vitro myelopoiesis using inhibitors of proteolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506020

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00596-09

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release_ykgkhctymrhwlg37vgcocspahi

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