(Q24643003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

0 references

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Gregory P McLennan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alexi Kiss

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mayumi Miyatake

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mariana M Belcheva

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Kari T Chambers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

John J Pozek

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Yasmin Mohabbat

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Robert A Moyer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Carmine J Coscia

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

10 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

17 January 2020

published in

1 reference

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17 January 2020

volume

107

1 reference

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17 January 2020

issue

6

1 reference

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17 January 2020

page(s)

1753-1765

1 reference

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describes a project that uses

17 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2606093/fullTextXML

inferred from PubMed Central ID database lookup

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Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase

7 April 2017

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Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase

7 April 2017

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Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes

7 April 2017

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Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes

7 April 2017

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beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

7 April 2017

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Mitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells: evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade

7 April 2017

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7 April 2017

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7 April 2017

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Glia-derived D-serine controls NMDA receptor activity and synaptic memory

7 April 2017

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7 April 2017

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7 April 2017

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Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube

7 April 2017

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Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

7 April 2017

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Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits

7 April 2017

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Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures

7 April 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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7 April 2017

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Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system

7 April 2017

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Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism

27 September 2017

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Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans.

27 September 2017

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Genome-wide transcriptional analysis of the human cell cycle identifies genes differentially regulated in normal and cancer cells

27 September 2017

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New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors

27 September 2017

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Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor

27 September 2017

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An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization

27 September 2017

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Astrocyte dysfunction in neurological disorders: a molecular perspective

27 September 2017

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27 September 2017

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beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

27 September 2017

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Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues

27 September 2017

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27 September 2017

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Pathobiology of dynorphins in trauma and disease

27 September 2017

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Salvinorin A: a novel and highly selective kappa-opioid receptor agonist

27 September 2017

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Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

27 September 2017

1 reference

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Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine.

27 September 2017

1 reference

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Roles of Src and epidermal growth factor receptor transactivation in transient and sustained ERK1/2 responses to gonadotropin-releasing hormone receptor activation

27 September 2017

1 reference

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mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation

27 September 2017

1 reference

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Diversity of the endogenous opioid system in development. Novel signal transduction translates multiple extracellular signals into neural cell growth and differentiation.

27 September 2017

1 reference

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Opioid modulation of extracellular signal-regulated protein kinase activity is ras-dependent and involves Gbetagamma subunits

27 September 2017

1 reference

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Egr-1 activates basic fibroblast growth factor transcription. Mechanistic implications for astrocyte proliferation

27 September 2017

1 reference

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kappa-Opioid agonist modulation of [3H]thymidine incorporation into DNA: evidence for the involvement of pertussis toxin-sensitive G protein-coupled phosphoinositide turnover

27 September 2017

1 reference

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Opioids inhibit endothelin-mediated DNA synthesis, phosphoinositide turnover, and Ca2+ mobilization in rat C6 glioma cells

27 September 2017

1 reference

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Dynorphins modulate DNA synthesis in fetal brain cell aggregates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Morphine alters astrocyte growth in primary cultures of mouse glial cells: evidence for a direct effect of opiates on neural maturation

27 September 2017

1 reference

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Directed establishment of rat brain cell lines with the phenotypic characteristics of type 1 astrocytes

27 September 2017

1 reference

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Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes.

27 September 2017

1 reference

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Astroglial differentiation is required for support of neurite outgrowth.

30 May 2018

1 reference

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Characterization of opioid-dependent glial development in dissociated and organotypic cultures of mouse central nervous system: critical periods and target specificity

30 May 2018

1 reference

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Ectopia of meningeal fibroblasts and reactive gliosis in the cerebral cortex of the mouse model of muscle-eye-brain disease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Direct astrocytic contacts regulate local maturation of dendritic spines.

28 November 2018

1 reference

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Astrocytes put down the broom and pick up the baton.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Morphine modulates chemokine gene regulation in normal human astrocytes

28 November 2018

1 reference

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Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Mu opioid transactivation and down-regulation of the epidermal growth factor receptor in astrocytes: implications for mitogen-activated protein kinase signaling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Apolipoprotein E deposition and astrogliosis are associated with maturation of beta-amyloid plaques in betaAPPswe transgenic mouse: Implications for the pathogenesis of Alzheimer's disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Basic fibroblast growth factor-induced proliferation of primary astrocytes. evidence for the involvement of sphingomyelin biosynthesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Evidence for transduction of mu but not kappa opioid modulation of extracellular signal-regulated kinase activity by G(z) and G(12) proteins

28 November 2018

1 reference

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HIV encephalitis, proviral load and dementia in drug users and homosexuals with AIDS. Effect of neocortical involvement

28 November 2018

1 reference

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Coupling of ETB endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606093

Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics

28 November 2018

1 reference

12 December 2020

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

1 reference

12 December 2020

Biomodulatory role of ceramide in basic fibroblast growth factor-induced proliferation of cerebellar astrocytes in primary culture

1 reference

12 December 2020

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

1 reference

12 December 2020

10.1111/J.1471-4159.2008.05745.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19014370%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19014370

1 reference