(Q24652951)

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A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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author name string

Brian L Henry

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Bernhard H Monien

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

language of work or name

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publication date

5 September 2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

282

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

44

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

31891-31899

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Fixed dose subcutaneous low molecular weight heparins versus adjusted dose unfractionated heparin for venous thromboembolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

7 April 2017

On the size of the active site in proteases. I. Papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

7 April 2017

Novel chemo-enzymatic oligomers of cinnamic acids as direct and indirect inhibitors of coagulation proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

An overview of the structure and function of thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

New anticoagulant agents: direct thrombin inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Heterogeneity of synthetic factor Xa inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Heparin-induced thrombocytopenia: clinical manifestations and management strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Molecular recognition mechanisms of thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Lignin primary structures and dirigent sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

The safety of fondaparinux for the prevention and treatment of venous thromboembolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Directing thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Fondaparinux: an update on new study results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Peptidomimetic thrombin inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Structural characterization of human liver heparan sulfate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Mass spectrometry in the biosynthetic and structural investigation of lignins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

New antithrombin-based anticoagulants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Heparin-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Heparin and heparan sulfate: structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Direct thrombin inhibitors in acute coronary syndromes: present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Oligosaccharide mapping of low molecular weight heparins: structure and activity differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Physical evidence for an apolar binding site near the catalytic center of human α-thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

28 September 2017

Antithrombin. A bloody important serpin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

30 May 2018

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643123

30 May 2018

The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704257200

21 January 2018

Crystal structure of thrombin bound to heparin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704257200

21 January 2018

Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704257200

21 January 2018

Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin specificity with tripeptide chromogenic substrates: comparison of human and bovine thrombins with and without fibrinogen clotting activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of substrate composition, pH and other variables on tissue factor enhancement of factor VIIa activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of thrombin by antithrombin is accompanied by inactivation of regulatory exosite I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of exosite ligands to human thrombin. Re-evaluation of allosteric linkage between thrombin exosites I and II

1 reference

https://pubmed.ncbi.nlm.nih.gov/17804413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M704257200

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17804413%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

ResearchGate publication ID

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