(Q24658277)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1

1 reference

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31 January 2020

author name string

M Suzette Blanchard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Carla A Theimer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Blanka Sengerová

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Purnima Singh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Valerie Chavez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Fei Liu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Jane A Grasby

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Binghui Shen

9

1 reference

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31 January 2020

language of work or name

English

0 references

publication date

11 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

31 January 2020

published in

1 reference

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31 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

33

1 reference

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31 January 2020

page(s)

22184-22194

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describes a project that uses

31 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2755943/fullTextXML

inferred from PubMed Central ID database lookup

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

7 April 2017

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Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage

7 April 2017

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Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The Fen1 extrahelical 3'-flap pocket is conserved from archaea to human and regulates DNA substrate specificity

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding

28 September 2017

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RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

28 September 2017

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Partial functional deficiency of E160D flap endonuclease-1 mutant in vitro and in vivo is due to defective cleavage of DNA substrates

28 September 2017

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Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.

28 September 2017

1 reference

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Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli

28 September 2017

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Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.

28 September 2017

1 reference

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Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

28 September 2017

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Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

28 September 2017

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Triplet repeat expansion generated by DNA slippage is suppressed by human flap endonuclease 1.

28 September 2017

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Flexible loops and helical arches

30 May 2018

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Flap endonuclease homologs in archaebacteria exist as independent proteins.

30 May 2018

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers

21 January 2018

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Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants.

21 January 2018

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Three metal ions participate in the reaction catalyzed by T5 flap endonuclease.

21 January 2018

1 reference

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Interaction interface of human flap endonuclease-1 with its DNA substrates

21 January 2018

1 reference

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Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate.

21 January 2018

1 reference

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Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Effect of flap modifications on human FEN1 cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Quantitative analysis of the effect of salt concentration on enzymatic catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Catalysis by ribonuclease A is limited by the rate of substrate association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

Non-nearest neighbor effects on the thermodynamics of unfolding of a model mRNA pseudoknot

21 January 2018

1 reference

12 December 2020

GNA trinucleotide loop sequences producing extraordinarily stable DNA minihairpins

1 reference

12 December 2020

A comparison of eubacterial and archaeal structure-specific 5'-exonucleases

1 reference

12 December 2020

Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases

1 reference

12 December 2020

Mixed-Effects Models in Sand S-PLUS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.015065

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1074/JBC.M109.015065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19525235%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

19525235

1 reference