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Mitochondrial reactive oxygen species: Do they extend or shorten animal lifespan?
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Europe PubMed Central
PubMed publication ID
26997500
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
title
Mitochondrial reactive oxygen species: Do they extend or shorten animal lifespan?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
main subject
reactive oxygen species
1 reference
based on heuristic
inferred from title
lifetime
1 reference
based on heuristic
inferred from title
author
Alberto Sanz
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
author name string
Alberto Sanz
series ordinal
1
0 references
language of work or name
English
0 references
publication date
17 March 2016
1 reference
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Europe PubMed Central
PubMed publication ID
26997500
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
Biochimica et Biophysica Acta
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Europe PubMed Central
PubMed publication ID
26997500
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
volume
1857
1 reference
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Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
1116-1126
1 reference
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Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
cites work
Paraquat exposure and Sod2 knockdown have dissimilar impacts on the Drosophila melanogaster carbonylated protein proteome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imaging ROS signaling in cells and animals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical diagnosis of mitochondrial disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Testing the vicious cycle theory of mitochondrial ROS production: effects of H2O2 and cumene hydroperoxide treatment on heart mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of superoxide and hydroxyl radicals in phospholipid peroxidation catalysed by iron salts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of age on superoxide dismutase, catalase, glutathione reductase, inorganic peroxides, TBA-reactive material, GSH/GSSG, NADPH/NADP+ and NADH/NAD+ in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of hydrogen peroxide administration on life span, superoxide dismutase, catalase, and glutathione in the adult housefly, Musca domestica.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A site-specific mechanism for free radical induced biological damage: the essential role of redox-active transition metals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxiredoxins as preferential targets in H2O2-induced signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular mechanism and cellular functions of mitochondrial division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carbonylation of mitochondrial proteins in Drosophila melanogaster during aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free radicals and antioxidants in normal physiological functions and human disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide flashes in single mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hallmarks of aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle mitohormesis promotes longevity via systemic repression of insulin signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sites and topology of mitochondrial superoxide production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ageing alters the supramolecular architecture of OxPhos complexes in rat brain cortex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trends in oxidative aging theories
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related alterations in oxidatively damaged proteins of mouse skeletal muscle mitochondrial electron transport chain complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress, inflammation, and cancer: how are they linked?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The redox stress hypothesis of aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reductive stress in young healthy individuals at risk of Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generator-specific targets of mitochondrial reactive oxygen species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison between the effects of aging and hyperoxia on glutathione redox state and protein mixed disulfides in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial electron transport chain dysfunction during development does not extend lifespan in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Respiratory active mitochondrial supercomplexes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative in vivo redox sensors uncover oxidative stress as an early event in life
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial modulation: reversible phosphorylation takes center stage?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling functions of reactive oxygen species.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitonuclear protein imbalance as a conserved longevity mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 'mitoflash' probe cpYFP does not respond to superoxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cellular production of hydrogen peroxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How mitochondria produce reactive oxygen species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's Disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin-deficient mice are not a robust model of parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of mitochondrial respiration by endogenous nitric oxide: a critical step in Fas signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide dismutase is dispensable for normal animal lifespan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex III releases superoxide to both sides of the inner mitochondrial membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is the mitochondrial free radical theory of aging intact?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial respiratory supercomplex association limits production of reactive oxygen species from complex I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The free radical theory of aging revisited: the cell signaling disruption theory of aging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aging: a theory based on free radical and radiation chemistry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paraquat neurotoxicity is distinct from that of MPTP and rotenone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redox-sensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biologic clock: the mitochondria?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production--a correction using glutathione depletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rates of behavior and aging specified by mitochondrial function during development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of murine life span by overexpression of catalase targeted to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Supercomplex assembly determines electron flux in the mitochondrial electron transport chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations causing mitochondrial disease: What is new and what challenges remain?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free radicals in the physiological control of cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between human aging muscle and oxidative system pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress and diabetic complications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rotenone, paraquat, and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aconitase causes iron toxicity in Drosophila pink1 mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G×G×E for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial and cytoplasmic ROS have opposing effects on lifespan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial encephalomyopathy in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vascular aging: chronic oxidative stress and impairment of redox signaling-consequences for vascular homeostasis and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of oxidative stress in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial complex I: a central regulator of the aging process.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBABIO.2016.03.018
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.BBABIO.2016.03.018
1 reference
stated in
Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed publication ID
26997500
1 reference
stated in
Europe PubMed Central
PubMed publication ID
26997500
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997500%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
ResearchGate publication ID
298796961
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