(Q26777261)

Denis Vivien

6

0 references

Arnaud Chevilley

1

Arnaud Chevilley

0 references

Flavie Lesept

2

Flavie Lesept

0 references

Sophie Lenoir

3

Sophie Lenoir

0 references

Jérôme Parcq

5

Frontiers in Cellular Neuroscience

Jérôme Parcq

0 references

language of work or name

English

0 references

publication date

2015

0 references

published in

0 references

volume

9

0 references

page(s)

415

0 references

cites work

Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Key role of tissue plasminogen activator in neurovascular coupling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Regulation of brain proteolytic activity is necessary for the in vivo function of NMDA receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Excessive autophagy contributes to neuron death in cerebral ischemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator is a potent activator of PDGF-CC

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator: peptide analyses confirm an indirectly derived amino acid sequence, identify the active site serine residue, establish glycosylation sites, and localize variant differences

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

A functional role for Nlrp6 in intestinal inflammation and tumorigenesis

7 April 2017

1 reference

https://api.crossref.org/works/10.3389/FNCEL.2015.00415

Tissue plasminogen activator for acute ischemic stroke

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Stressed neurons protect themselves by a tissue-type plasminogen activator-mediated EGFR-dependent mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Randomized assessment of rapid endovascular treatment of ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Endovascular therapy for ischemic stroke with perfusion-imaging selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Hypoxia-ischemia or excitotoxin-induced tissue plasminogen activator- dependent gelatinase activation in mice neonate brain microvessels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator mediates neuronal detection and adaptation to metabolic stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator regulates Purkinje neuron development and survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2-CREB-ATF3 signaling pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

First structural model of full-length human tissue-plasminogen activator: a SAXS data-based modeling study.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator prevents white matter damage following stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The tissue-type plasminogen activator story

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Antifibrinolytic agents reduce tissue plasminogen activator-mediated neuronal toxicity in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator protects hippocampal neurons from oxygen-glucose deprivation injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

"Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Basic and clinical aspects of fibrinolysis and thrombolysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Purification and partial characterization of plasminogen activator from human uterine tissue

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Purification and characterization of human vascular plasminogen activator derived from blood vessel perfusates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Functional occurrence of the interaction of tissue plasminogen activator with the NR1 Subunit of N-methyl-D-aspartate receptors during stroke

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

A PROTEOLYTIC ENZYME OF SERUM: CHARACTERIZATION, ACTIVATION, AND REACTION WITH INHIBITORS.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

FURTHER INVESTIGATIONS ON THE MODE OF ACTION OF SUBSTANCES INHIBITING TUMOR GROWTH AND ON IMMUNIZATION AGAINST THESE SUBSTANCES.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Enzymatic properties of the one- and two-chain form of tissue plasminogen activator

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Variants of human tissue-type plasminogen activator. Fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Carbohydrate structures of human tissue plasminogen activator expressed in Chinese hamster ovary cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Glycosylation at Asn-184 inhibits the conversion of single-chain to two-chain tissue-type plasminogen activator by plasmin.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Signal and propeptide processing of human tissue plasminogen activator: activity of a pro-tPA derivative

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

The effect of polymerised fibrin on the catalytic activities of one-chain tissue-type plasminogen activator as revealed by an analogue resistant to plasmin cleavage.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Fibrinolysis in the animal organism

19 June 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Characterization of oligosaccharides in recombinant tissue plasminogen activator produced in Chinese hamster ovary cells: two decades of analytical technology development

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue plasminogen activator is required for striatal post-ischemic synaptic potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Inhibition of endothelial cell proliferation by the recombinant kringle domain of tissue-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Interaction of mutants of tissue-type plasminogen activator with liver cells: effect of domain deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Non-proteolytic neurotrophic effects of tissue plasminogen activator on cultured mouse cerebrocortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Effect of neuroserpin in a neonatal hypoxic-ischemic injury model ex vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue plasminogen activator and NMDA receptor cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Memantine improves safety of thrombolysis for stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Modulation of zinc toxicity by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

The regulation by fibrinogen and fibrin of tissue plasminogen activator kinetics and inhibition by plasminogen activator inhibitor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Tissue-type plasminogen activator is not required for kainate-induced motoneuron death in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Fibrinolysis; its mechanism and significance.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4607783

Isolation of a Soluble Fibrinolytic Activator from Animal Tissue

28 November 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2015.00415

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

21 January 2018

1 reference

12 December 2020

Tissue type plasminogen activator amplifies hemoglobin-induced neurotoxicity in rat neuronal cultures

1 reference

12 December 2020

The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator

1 reference

12 December 2020

N-methyl-D-aspartate receptor blockade enhances neuronal apoptosis induced by serum deprivation

1 reference

12 December 2020

Differential proteolysis and evidence for a residue exchange in tissue plasminogen activator suggest possible association between two types of protein microheterogeneity

1 reference

12 December 2020

Kringle glycosylation in a modified human tissue plasminogen activator improves functional properties

1 reference

12 December 2020

Proteolytic activation of tissue plasminogen activator by plasma and tissue enzymes

1 reference

12 December 2020

On the presence of a proteolytic enzyme in the normal serum of the ox

1 reference

12 December 2020

Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser

1 reference

12 December 2020

Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis

1 reference

12 December 2020

Purification and identification of two structural variants of porcine tissue plasminogen activator by affinity adsorption on fibrin

1 reference

12 December 2020

Large-scale purification of human tissue-type plasminogen activator using monoclonal antibodies

1 reference

12 December 2020

Purification of human tissue-type plasminogen activator in centigram quantities from human melanoma cell culture fluid and its conditioning for use in vivo

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator

1 reference

12 December 2020

The plasmin system is induced by and degrades amyloid-beta aggregates

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNCEL.2015.00415

1 reference

1 reference

1 reference

PubMed publication ID

26528141

1 reference