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From genetics of inflammatory bowel disease towards mechanistic insights
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PubMed
title
From genetics of inflammatory bowel disease towards mechanistic insights
(English)
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stated in
PubMed
main subject
inflammatory bowel diseases
0 references
inflammation
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author
Ramnik J Xavier
series ordinal
2
object named as
Ramnik J. Xavier
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Crossref
author name string
Daniel B. Graham
series ordinal
1
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Crossref
language of work or name
English
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stated in
PubMed
publication date
August 2013
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stated in
PubMed
published in
Trends in Immunology
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stated in
PubMed
volume
34
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PubMed
issue
8
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PubMed
page(s)
371-8
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PubMed
cites work
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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
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Genome-wide association identifies multiple ulcerative colitis susceptibility loci
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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
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NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2
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Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
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Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
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7 April 2017
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
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Mapping and analysis of chromatin state dynamics in nine human cell types
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Systematic localization of common disease-associated variation in regulatory DNA
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7 April 2017
lincRNAs act in the circuitry controlling pluripotency and differentiation
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Genetics and pathogenesis of inflammatory bowel disease
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Bifidobacteria can protect from enteropathogenic infection through production of acetate
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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
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The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus
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Cloning, expression, and functional characterization of TL1A-Ig
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28 September 2017
Complex roles of caspases in the pathogenesis of inflammatory bowel disease
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RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition
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The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
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Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages
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Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine.
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28 September 2017
Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease
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Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
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Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding
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Cutting edge: regulation of intestinal inflammation and barrier function by IL-17C.
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p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation.
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Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.
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Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes
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28 September 2017
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.
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IL-10R polymorphisms are associated with very-early-onset ulcerative colitis
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Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
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28 September 2017
Protein tyrosine phosphatases in lymphocyte activation and autoimmunity
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28 September 2017
FLASH assembly of TALENs for high-throughput genome editing
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28 September 2017
Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.
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28 September 2017
Resolving the variable genome and epigenome in human disease.
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28 September 2017
Cofactors required for TLR7- and TLR9-dependent innate immune responses
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28 September 2017
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
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Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
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A transcription activator-like effector toolbox for genome engineering
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28 September 2017
Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype
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28 September 2017
FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection
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Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.
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Genome-wide expression profiling implicates a MAST3-regulated gene set in colonic mucosal inflammation of ulcerative colitis patients
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28 September 2017
Metagenomics and personalized medicine
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28 September 2017
The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell function
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An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians
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28 September 2017
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
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28 September 2017
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
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28 September 2017
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
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A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.
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28 September 2017
Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium
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28 September 2017
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
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28 September 2017
MAST3: a novel IBD risk factor that modulates TLR4 signaling
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Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon
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Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.
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Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA.
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Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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31 May 2018
In vivo genome editing using a high-efficiency TALEN system
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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31 May 2018
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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31 May 2018
Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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31 May 2018
Post-transcriptional control of candidate risk genes for type 1 diabetes by rare genetic variants.
1 reference
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PubMed Central
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28 November 2018
Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8 + Intraepithelial Lymphocytes in a Mouse Model for Crohn's Disease-like Ileitis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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28 November 2018
Macrophage-stimulating protein polymorphism rs3197999 is associated with a gain of function: implications for inflammatory bowel disease.
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28 November 2018
Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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28 November 2018
Role of genetic and environmental factors in British twins with inflammatory bowel disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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28 November 2018
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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28 November 2018
T cell- and B cell-independent adaptive immunity mediated by natural killer cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3735683
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28 November 2018
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
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https://pubmed.ncbi.nlm.nih.gov/23639549
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/23639549
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulatory dendritic cells pulsed with carbonic anhydrase I protect mice from colitis induced by CD4+CD25- T cells
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https://pubmed.ncbi.nlm.nih.gov/23639549
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Unfolded protein responses in the intestinal epithelium: sensors for the microbial and metabolic environment
1 reference
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PubMed
reference URL
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
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7 January 2021
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inferred from DOI database lookup
Identifiers
DOI
10.1016/J.IT.2013.04.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4464104
Fatcat ID
release_zaugvsxq6jhv5nym7nzgokua5a
0 references
OpenCitations bibliographic resource ID
4464104
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4464104
PMC publication ID
3735683
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4464104
PubMed publication ID
23639549
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4464104
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