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Olfactomedin proteins: central players in development and disease
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scholarly article
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review article
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Europe PubMed Central
title
Olfactomedin proteins: central players in development and disease
(English)
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PubMed
author
Robert R H Anholt
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Robert R. H. Anholt
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language of work or name
English
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publication date
2014
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published in
Frontiers in Cell and Developmental Biology
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volume
2
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PubMed
page(s)
6
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PubMed
cites work
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High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex
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7 April 2017
Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathway
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7 April 2017
Myocilin is a modulator of Wnt signaling
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PubMed Central
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Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells
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PubMed Central
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7 April 2017
The glycoprotein hGC-1 binds to cadherin and lectins
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7 April 2017
The number of people with glaucoma worldwide in 2010 and 2020
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7 April 2017
Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase
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7 April 2017
Optimedin: a novel olfactomedin-related protein that interacts with myocilin
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PubMed Central
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7 April 2017
Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues
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PubMed Central
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7 April 2017
Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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7 April 2017
pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1
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PubMed Central
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7 April 2017
Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth
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PubMed Central
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7 April 2017
The Optimedin gene is a downstream target of Pax6
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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7 April 2017
Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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7 April 2017
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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7 April 2017
Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Olfactomedin 4 (GW112, hGC-1) is an independent prognostic marker for survival in patients with colorectal cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Depletion of OLFM4 gene inhibits cell growth and increases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced-apoptosis in gastric cancer cells
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PubMed Central
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28 September 2017
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
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28 September 2017
Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier.
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PubMed Central
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28 September 2017
A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker
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PubMed Central
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28 September 2017
GRIM-19 function in cancer development
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PubMed Central
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28 September 2017
Genes of the unfolded protein response pathway harbor risk alleles for primary open angle glaucoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Olfactomedin 4 suppresses prostate cancer cell growth and metastasis via negative interaction with cathepsin D and SDF-1.
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PubMed Central
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28 September 2017
Olfactomedin 4, a novel marker for the differentiation and progression of gastrointestinal cancers
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PubMed Central
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28 September 2017
Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis
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PubMed Central
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28 September 2017
A structural overview of the PDI family of proteins
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PubMed Central
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28 September 2017
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2′-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Development of autoantibody signatures as novel diagnostic biomarkers of non-small cell lung cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Secreted gliomedin is a perinodal matrix component of peripheral nerves
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Olfactomedin 4 promotes S-phase transition in proliferation of pancreatic cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Optimedin induces expression of N-cadherin and stimulates aggregation of NGF-stimulated PC12 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Functional analysis of the glaucoma-causing TIGR/myocilin protein: integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
GW112, a novel antiapoptotic protein that promotes tumor growth
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC).
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Amassin, an olfactomedin protein, mediates the massive intercellular adhesion of sea urchin coelomocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
The latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Molecular evolution of olfactomedin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Identification of a gene that causes primary open angle glaucoma.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Molecular cloning of olfactomedin, an extracellular matrix protein specific to olfactory neuroepithelium
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 September 2017
OLFM4 is associated with lymph node metastasis and poor prognosis in patients with gastric cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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31 May 2018
Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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31 May 2018
Noelin-1 is a secreted glycoprotein involved in generation of the neural crest
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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31 May 2018
Prevalence of mutations in TIGR/Myocilin in patients with adult and juvenile primary open-angle glaucoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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31 May 2018
Targeting Olfactomedin-like 3 Inhibits Tumor Growth by Impairing Angiogenesis and Pericyte Coverage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Olfactomedin 4 is a marker for progression of cervical neoplasia.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
The regulation of OLFM4 expression in myeloid precursor cells relies on NF-kappaB transcription factor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Noelins modulate the timing of neuronal differentiation during development
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Elucidation of subfamily segregation and intramolecular coevolution of the olfactomedin-like proteins by comprehensive phylogenetic analysis and gene expression pattern assessment.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Overexpression and properties of wild-type and Tyr437His mutated myocilin in the eyes of transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
A conserved postsynaptic transmembrane protein affecting neuromuscular signaling in Caenorhabditis elegans.
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PubMed Central
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28 November 2018
Dorsalization of the neural tube by Xenopus tiarin, a novel patterning factor secreted by the flanking nonneural head ectoderm
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28 November 2018
The secreted glycoprotein Noelin-1 promotes neurogenesis in Xenopus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206993
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28 November 2018
Characterization and differential expression of a human gene family of olfactomedin-related proteins
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/25364714
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of olfactomedin 4 and claudin-18 in serrated neoplasia of the colorectum: a characteristic pattern is associated with sessile serrated lesion
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25364714
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Diversity of olfactomedin proteins in the sea urchin
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25364714
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Formation of the extracellular mucous matrix of olfactory neuroepithelium: Identification of partially glycosylated and nonglycosylated precursors of olfactomedin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25364714
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Olfactomedin: purification, characterization, and localization of a novel olfactory glycoprotein
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25364714
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FCELL.2014.00006
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2643557
OpenCitations bibliographic resource ID
2643557
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2643557
PMC publication ID
4206993
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2643557
PubMed publication ID
25364714
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2643557
ResearchGate publication ID
267753954
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