(Q26852917)

6

0 references

author name string

Katharine Briggs

1

1 reference

Montserrat Cases

2

1 reference

David J. Heard

3

1 reference

François Pognan

5

1 reference

Christof H. Schwab

7

1 reference

Thomas Steger-Hartmann

8

1 reference

Andreas Sutter

9

1 reference

David K. Watson

10

1 reference

Jörg D. Wichard

11

1 reference

language of work or name

1 reference

2012

1 reference

International Journal of Molecular Sciences

21 March 2012

2 references

26 August 2020

23 November 2020

3 references

26 August 2020

23 November 2020

13

1 reference

issue

3

1 reference

page(s)

3820-46

1 reference

Creative Commons Attribution 3.0 Unported

copyright license

2 references

Europe PubMed Central

26 August 2020

Collaborative development of predictive toxicology applications

Europe PubMed Central

23 November 2020

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Mechanisms of hepatotoxicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Text-mining approaches in molecular biology and biomedicine

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Probabilistic risk analysis: improving early drug development decision making

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Use of genotoxicity information in the development of integrated testing strategies (ITS) for skin sensitization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Anticipating drug side effects by comparative pharmacology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

The computational prediction of genotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

In silico tools for sharing data and knowledge on toxicity and metabolism: derek for windows, meteor, and vitic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Toxicity data informatics: supporting a new paradigm for toxicity prediction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Quantitative structure-activity relationship modeling of rat acute toxicity by oral exposure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

The hERG potassium channel and hERG screening for drug-induced torsades de pointes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Toxicological and clinical computational analysis and the US FDA/CDER.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Validation of an in vitro screen for phospholipidosis using a high-content biology platform

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Data integration: challenges for drug discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Cationic amphiphilic drugs and phospholipid storage disorder.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

A review of drug-induced lysosomal disorders of the liver in man and laboratory animals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

Cationic amphiphilic drug-induced phospholipidosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317745

A multiscale simulation system for the prediction of drug-induced cardiotoxicity

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Oral LD50 toxicity modeling and prediction of per- and polyfluorinated chemicals on rat and mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Descriptor collision and confusion: toward the design of descriptors to mask chemical structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Achieving confidence in mechanism for drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Developing structure-activity relationships for the prediction of hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Using Absolute and Relative Reasoning in the Prediction of the Potential Metabolism of Xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Using Argumentation for Absolute Reasoning about the Potential Toxicity of Chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

Using In Silico Tools in a Weight of Evidence Approach to Aid Toxicological Assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13033820

An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing

21 January 2018

1 reference

12 December 2020

The role of hepatic transporters in drug elimination

1 reference

12 December 2020

Handing over the baton: connecting medicinal chemistry with process R&D

1 reference

12 December 2020

Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models

1 reference

12 December 2020

Identifiers

0 references

1 reference

PubMed publication ID

22489185

1 reference