(Q26859010)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431722%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

PARPs and the DNA damage response (English)

2 references

PubMed

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26 January 2020

0 references

Fabricio Garmus Sousa

1

1 reference

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26 January 2020

Alexandre Escargueil

4

1 reference

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João Antonio Pêgas Henriques

26 January 2020

5

object named as

João A P Henriques

1 reference

26 January 2020

Renata Matuo

2

1 reference

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26 January 2020

Daniele G Soares

3

1 reference

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26 January 2020

Annette K Larsen

6

1 reference

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26 January 2020

Jenifer Saffi

7

1 reference

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26 January 2020

language of work or name

1 reference

19 March 2012

1 reference

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26 January 2020

2 references

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26 January 2020

volume

33

2 references

PubMed

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26 January 2020

issue

8

2 references

PubMed

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26 January 2020

page(s)

1433-1440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431722%20AND%20SRC:MED&resulttype=core&format=json

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

26 January 2020

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DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

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Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications.

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21 January 2018

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The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.

21 January 2018

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21 January 2018

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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

21 January 2018

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Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

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Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

21 January 2018

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PARP-3 and APLF function together to accelerate nonhomologous end-joining

21 January 2018

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A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

21 January 2018

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Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2

21 January 2018

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Toward specific functions of poly(ADP-ribose) polymerase-2.

21 January 2018

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Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3

21 January 2018

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PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

21 January 2018

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Learning how to read ADP-ribosylation

21 January 2018

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Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

21 January 2018

1 reference

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Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis

21 January 2018

1 reference

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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

21 January 2018

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PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

21 January 2018

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Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

21 January 2018

1 reference

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Mechanism of early biphasic activation of poly(ADP-ribose) polymerase-1 in response to ultraviolet B radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Apurinic/apyrimidinic (AP) site recognition by the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair

21 January 2018

1 reference

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Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.

21 January 2018

1 reference

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Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair

21 January 2018

1 reference

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Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks

21 January 2018

1 reference

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Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition

21 January 2018

1 reference

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DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression

21 January 2018

1 reference

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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice

21 January 2018

1 reference

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p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.

21 January 2018

1 reference

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Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

21 January 2018

1 reference

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PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development

21 January 2018

1 reference

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

21 January 2018

1 reference

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PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery.

21 January 2018

1 reference

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Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair

21 January 2018

1 reference

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Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation

21 January 2018

1 reference

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A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

21 January 2018

1 reference

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Modulation of nucleosome-binding activity of FACT by poly(ADP-ribosyl)ation

21 January 2018

1 reference

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A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

21 January 2018

1 reference

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Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

21 January 2018

1 reference

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Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

21 January 2018

1 reference

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APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells.

21 January 2018

1 reference

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

1 reference

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Poly(ADP-ribose) (PAR) polymer is a death signal

21 January 2018

1 reference

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Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Regulation of poly(ADP-ribose) polymerase-1 by DNA structure-specific binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Could TCTP contribute to Armin Braun's paradigm of tumor reversion in plants?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

New functions for an ancient domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition

21 January 2018

1 reference

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The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

21 January 2018

1 reference

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ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

What histone code for DNA repair?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Mitochondrial and nuclear cross talk in cell death: parthanatos

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Targeted therapy for cancer using PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

PARP inhibition: PARP1 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Making the best of PARP inhibitors in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

PARP inhibition: targeting the Achilles' heel of DNA repair to treat germline and sporadic ovarian cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Inhibition of poly(ADP-ribose) polymerase (PARP) induces apoptosis in lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Poly(ADP-ribose) polymerase inhibitors in cancer treatment: a clinical perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Phase I study of PARP inhibitor ABT-888 in combination with topotecan in adults with refractory solid tumors and lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS132

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS132

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431722%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431722%20AND%20SRC:MED&resulttype=core&format=json