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Induced pluripotent stem cells as a disease modeling and drug screening platform
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title
Induced pluripotent stem cells as a disease modeling and drug screening platform
(English)
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PubMed
main subject
drug screening
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author
Joseph C. Wu
series ordinal
3
object named as
Joseph C. Wu
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Crossref
author name string
Antje D. Ebert
series ordinal
1
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Ping Liang
series ordinal
2
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language of work or name
English
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publication date
October 2012
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PubMed
published in
Journal of Cardiovascular Pharmacology
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PubMed
volume
60
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stated in
PubMed
issue
4
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PubMed
page(s)
408-16
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PubMed
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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
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Disease-specific induced pluripotent stem cells
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Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
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Human induced pluripotent stem cells free of vector and transgene sequences
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Immunogenicity of induced pluripotent stem cells
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A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
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Patient-specific induced pluripotent stem-cell models for long-QT syndrome
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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
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Stem cells for drug screening
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Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
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Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells
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Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review.
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Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells
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Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
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28 September 2017
Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells.
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28 September 2017
Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors
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28 September 2017
Applications of patient-specific induced pluripotent stem cells; focused on disease modeling, drug screening and therapeutic potentials for liver disease
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28 September 2017
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability
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28 September 2017
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome)
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28 September 2017
Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome
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28 September 2017
Induced pluripotency: history, mechanisms, and applications
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28 September 2017
Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes
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28 September 2017
Quantitative comparison of genome-wide DNA methylation mapping technologies.
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28 September 2017
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.
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28 September 2017
High-content screening of small compounds on human embryonic stem cells.
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28 September 2017
Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening.
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28 September 2017
Patient-specific pluripotent stem cells become even more accessible
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28 September 2017
Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration
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28 September 2017
Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies
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28 September 2017
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
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28 September 2017
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
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28 September 2017
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28 September 2017
Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes
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28 September 2017
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.
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28 September 2017
Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.
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28 September 2017
Recent progress in congenital long QT syndrome
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28 September 2017
Drug-induced QT prolongation and sudden death
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28 September 2017
Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells
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28 September 2017
Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes
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28 September 2017
Complete genetic correction of ips cells from Duchenne muscular dystrophy
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28 September 2017
Technical challenges in using human induced pluripotent stem cells to model disease
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28 September 2017
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28 September 2017
Generation of functional human hepatic endoderm from human induced pluripotent stem cells
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28 September 2017
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
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28 September 2017
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.
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28 September 2017
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28 September 2017
Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Strategies and new developments in the generation of patient-specific pluripotent stem cells
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28 September 2017
The development of new concepts for assessing reproductive toxicity applicable to large scale toxicological programmes.
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28 September 2017
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28 September 2017
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28 September 2017
The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates
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28 September 2017
The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications
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28 September 2017
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28 September 2017
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28 September 2017
Cardiac channelopathies: from men to mice
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28 September 2017
Small molecules that induce cardiomyogenesis in embryonic stem cells
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28 September 2017
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28 September 2017
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28 September 2017
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
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28 September 2017
Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
The long QT syndrome. A review of recent molecular genetic and physiologic discoveries
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28 September 2017
A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects
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31 May 2018
Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells
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31 May 2018
QT interval prolongation: preclinical and clinical testing arrhythmogenesis in drugs and regulatory implications.
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31 May 2018
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31 May 2018
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31 May 2018
Development of patient-specific neurons in schizophrenia using induced pluripotent stem cells
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28 November 2018
Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells.
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28 November 2018
A high-throughput multiplexed screening assay for optimizing serum-free differentiation protocols of human embryonic stem cells.
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28 November 2018
Human and murine embryonic stem cell-derived cardiomyocytes serve together as a valuable model for drug safety screening
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28 November 2018
Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs
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28 November 2018
Benchmarking safety pharmacology regulatory packages and best practice
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28 November 2018
Methodology used in safety pharmacology: appraisal of the state-of-the-art, the regulatory issues and new directions
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28 November 2018
Tumor progression in hepatocellular carcinoma may be mediated by p53 mutation
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based on heuristic
inferred from PubMed ID database lookup
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1 reference
stated in
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https://pubmed.ncbi.nlm.nih.gov/22240913
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human-induced pluripotent stem cells: derivation, propagation, and freezing in serum- and feeder layer-free culture conditions
1 reference
stated in
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https://pubmed.ncbi.nlm.nih.gov/22240913
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
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1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22240913
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1097/FJC.0B013E318247F642
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1215578
OpenCitations bibliographic resource ID
1215578
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1215578
PMC publication ID
3343213
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1215578
PubMed publication ID
22240913
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1215578
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