(Q26865892)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

From development to dysfunction: microglia and the complement cascade in CNS homeostasis (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Matthew Zabel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Wolff M Kirsch

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

1 reference

16 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

published in

Ageing Research Reviews

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

12

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

749-756

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

Microglial interactions with synapses are modulated by visual experience

24 February 2020

cites work

1 reference

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Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 March 2017

1 reference

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Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

21 March 2017

1 reference

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The classical complement cascade mediates CNS synapse elimination

21 March 2017

1 reference

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A new class of membrane-bound chemokine with a CX3C motif

21 March 2017

1 reference

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Control of microglial neurotoxicity by the fractalkine receptor

21 March 2017

1 reference

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Fractalkine and CX 3 CR1 regulate hippocampal neurogenesis in adult and aged rats

21 March 2017

1 reference

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Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12.

21 March 2017

1 reference

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Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

21 March 2017

1 reference

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Synaptic pruning by microglia is necessary for normal brain development

21 March 2017

1 reference

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Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia: a sensor for pathological events in the CNS

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

A shift in microglial β-amyloid binding in Alzheimer's disease is associated with cerebral amyloid angiopathy.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Review: microglia of the aged brain: primed to be activated and resistant to regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Rational heterodoxy: cholesterol reformation of the amyloid doctrine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Genetic variation at CR1 increases risk of cerebral amyloid angiopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

C3-dependent mechanism of microglial priming relevant to multiple sclerosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Neuron-Microglia Dialogue and Hippocampal Neurogenesis in the Aged Brain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Synapse formation and maintenance by C1q family proteins: a new class of secreted synapse organizers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Enhanced synaptic connectivity and epilepsy in C1q knockout mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Immune proteins in brain development and synaptic plasticity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Neurotransmission selectively regulates synapse formation in parallel circuits in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

C1q: the perfect complement for a synaptic feast?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglial clearance function in health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Debris clearance by microglia: an essential link between degeneration and regeneration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Neurotransmitter receptors on microglia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Structural transitions of complement component C3 and its activation products

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia instruct subventricular zone neurogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Immune signalling in neural development, synaptic plasticity and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Migration and differentiation of neural precursor cells can be directed by microglia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Differential distribution and activation of microglia in the brain of male C57BL/6J mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Complement component C1q modulates the phagocytosis of Abeta by microglia

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Neurons express proteins of the classical complement pathway in Alzheimer disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Aggregation state-dependent activation of the classical complement pathway by the amyloid beta peptide.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Localization and cell association of C1q in Alzheimer's disease brain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Comparison of the effects of unilateral and bilateral eye closure on cortical unit responses in kittens

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Characterization of ameboid microglia isolated from developing mammalian brain.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Differential immunochemical markers reveal the normal distribution of brain macrophages and microglia in the developing rat brain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

The Microglial Reaction in the Rat Dorsal Hippocampus following Transient Forebrain Ischemia

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Plaque complement activation and cognitive loss in Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Evidence for synaptic stripping by cortical microglia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

What is immune privilege (not)?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Potentiation of cortical inhibition by visual deprivation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Microglia promote the death of developing Purkinje cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Neuronal localization of C1q in preclinical Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3700678

Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis

28 November 2018

1 reference

12 December 2020

Microglial motility in the rat facial nucleus following peripheral axotomy

1 reference

12 December 2020

Long-term synapse loss induced by focal blockade of postsynaptlc receptors

1 reference

12 December 2020

Displacement of synaptic terminals from regenerating motoneurons by microglial cells

1 reference

12 December 2020

10.1016/J.ARR.2013.02.001

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

23419464

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23419464%20AND%20SRC:MED&resulttype=core&format=json