(Q35734866)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

C3-dependent mechanism of microglial priming relevant to multiple sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Rossen Donev

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Bryan Paul Morgan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

6

Inge Huitinga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

4

Marieta M Ruseva

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1

Valeria Ramaglia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Timothy R Hughes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Xiaobo Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

James W Neal

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

4 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

965-970

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

Complement: a key system for immune surveillance and homeostasis

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

The role of the complement system and the activation fragment C5a in the central nervous system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Systemic inflammation and disease progression in Alzheimer disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Microglial physiology: unique stimuli, specialized responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Immunoglobulins and complement in postmortem multiple sclerosis tissue

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Membrane protein Crry maintains homeostasis of the complement system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Neuroinflammation and cognitive function in aged mice following minor surgery.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Downregulation of macrophage inhibitory molecules in multiple sclerosis lesions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Electron microscopy of the effect of gram-negative endotoxin on the blood-brain barrier

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

12 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Expression of the murine complement regulatory protein crry by glial cells and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Immunopathology of secondary-progressive multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Complement regulator factor H as a serum biomarker of multiple sclerosis disease state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Idazoxan attenuates spinal cord injury by enhanced astrocytic activation and reduced microglial activation in rat experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Soluble complement receptor 1 protects the peripheral nerve from early axon loss after injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

p53 regulates cellular resistance to complement lysis through enhanced expression of CD59

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H

25 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

25 September 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271873

IFN-γ priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and mRNA stability

15 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111924109

Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity

21 January 2018

1 reference

12 December 2020

Systemic blockade of complement C5a receptors reduces lipopolysacharride-induced responses in the paraventricular nucleus and the central amygdala

1 reference

12 December 2020

Attenuation of experimental autoimmune demyelination in complement-deficient mice

1 reference

12 December 2020

Cutting edge: C3, a key component of complement activation, is not required for the development of myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis in mice

1 reference

12 December 2020

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1111924109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22219359%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22219359

1 reference