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Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28
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scholarly article
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PubMed
title
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28
(English)
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stated in
PubMed
main subject
OMP-54f28
1 reference
based on heuristic
inferred from title
object named as
OMP-54f28
retrieved
21 February 2024
author name string
Phuong N. Le
series ordinal
1
1 reference
stated in
Crossref
Jessica D. McDermott
series ordinal
2
1 reference
stated in
Crossref
Antonio Jimeno
series ordinal
3
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
February 2015
1 reference
stated in
PubMed
published in
Pharmacology & Therapeutics
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stated in
PubMed
volume
146
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stated in
PubMed
page(s)
1-11
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PubMed
cites work
Frizzled homolog proteins, microRNAs and Wnt signaling in cancer
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Frizzled-8 as a putative therapeutic target in human lung cancer
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Activation of Wnt Signaling Pathway by Human Papillomavirus E6 and E7 Oncogenes in HPV16-Positive Oropharyngeal Squamous Carcinoma Cells
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Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
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21 March 2017
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
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Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma
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21 March 2017
Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2
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21 March 2017
Wnt signalling in lung development and diseases
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21 March 2017
Efficacy of Wnt-1 monoclonal antibody in sarcoma cells
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21 March 2017
The Frizzled family: receptors for multiple signal transduction pathways
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21 March 2017
LDL-receptor-related proteins in Wnt signal transduction
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21 March 2017
Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function
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A new secreted protein that binds to Wnt proteins and inhibits their activities
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21 March 2017
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
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21 March 2017
Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis
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21 March 2017
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton
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21 March 2017
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Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
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21 March 2017
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
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21 March 2017
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
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21 March 2017
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
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21 March 2017
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
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21 March 2017
Identification of selective inhibitors of cancer stem cells by high-throughput screening
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21 March 2017
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
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21 March 2017
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
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Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer
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21 March 2017
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
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21 March 2017
Functional interaction of beta-catenin with the transcription factor LEF-1
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21 March 2017
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21 March 2017
A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
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21 March 2017
Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells
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21 March 2017
Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway
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21 March 2017
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
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21 March 2017
A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells
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21 March 2017
Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway
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21 March 2017
Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres
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21 March 2017
The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model
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21 March 2017
Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells
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21 March 2017
Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1
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21 March 2017
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
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A role for Wnt signalling in self-renewal of haematopoietic stem cells
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21 March 2017
An LDL-receptor-related protein mediates Wnt signalling in mice
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21 March 2017
Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway
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21 March 2017
Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
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21 March 2017
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
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21 March 2017
beta-catenin is a target for the ubiquitin-proteasome pathway
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7 April 2017
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
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7 April 2017
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
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7 April 2017
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
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7 April 2017
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
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7 April 2017
Wnt proteins are lipid-modified and can act as stem cell growth factors
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7 April 2017
WNT signals are required for the initiation of hair follicle development
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7 April 2017
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
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7 April 2017
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
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7 April 2017
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
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7 April 2017
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
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7 April 2017
A new member of the frizzled family from Drosophila functions as a Wingless receptor
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7 April 2017
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
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7 April 2017
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7 April 2017
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28 September 2017
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28 September 2017
Activated hair follicle stem cells and Wnt/β-catenin signaling involve in pathnogenesis of sebaceous neoplasms
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28 September 2017
Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells
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28 September 2017
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28 September 2017
WNT16B from ovarian fibroblasts induces differentiation of regulatory T cells through β-catenin signal in dendritic cells
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28 September 2017
Overexpression of Wnt5a promotes angiogenesis in NSCLC.
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28 September 2017
Two Natural ent-kauranoids as Novel Wnt Signaling Inhibitors
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28 September 2017
Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cells
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PubMed Central
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28 September 2017
Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer.
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28 September 2017
Effect of niclosamide on basal-like breast cancers
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PubMed Central
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28 September 2017
Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
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PubMed Central
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28 September 2017
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
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28 September 2017
Salinomycin inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cell in vitro and suppresses tumor growth in vivo
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28 September 2017
XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway
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PubMed Central
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28 September 2017
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
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28 September 2017
Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium
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28 September 2017
Anticancer effects of niclosamide in human glioblastoma.
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PubMed Central
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28 September 2017
Regulation of Wnt signaling activity for growth suppression induced by quercetin in 4T1 murine mammary cancer cells
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PubMed Central
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28 September 2017
Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The β-catenin/TCF complex as a novel target of resveratrol in the Wnt/β-catenin signaling pathway
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PubMed Central
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28 September 2017
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Growth inhibition of ovarian tumor-initiating cells by niclosamide.
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PubMed Central
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28 September 2017
A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Salinomycin inhibits osteosarcoma by targeting its tumor stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
FZD7 has a critical role in cell proliferation in triple negative breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Frizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial intracranial transplantation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Targeting Wnt signaling: can we safely eradicate cancer stem cells?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
2,4-Diamino-quinazolines as inhibitors of beta-catenin/Tcf-4 pathway: Potential treatment for colorectal cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt signaling controls radiosensitivity via cyclooxygenase-2-mediated Ku expression in head and neck cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The Wnt/beta-catenin signaling pathway as a target in drug discovery
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Mining the Wnt pathway for cancer therapeutics
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Identification of a specific inhibitor of the dishevelled PDZ domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
An oncolytic adenovirus vector combining enhanced cell-to-cell spreading, mediated by the ADP cytolytic protein, with selective replication in cancer cells with deregulated wnt signaling
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
WIF1, a component of the Wnt pathway, is down‐regulated in prostate, breast, lung, and bladder cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Pinworm infestation in children: the problem and its treatment
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
beta-Catenin regulates vascular endothelial growth factor expression in colon cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt5a cloning, expression, and up-regulation in human primary breast cancers
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 September 2017
Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 September 2017
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Combined Wnt/β-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Localization of the gene for familial adenomatous polyposis on chromosome 5.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Phenocopies induced with antisense RNA identify the wingless gene.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
A new nomenclature for int-1 and related genes: the Wnt gene family
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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31 May 2018
Tumour supressor secreted frizzled related protein 1 regulates p53-mediated apoptosis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
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28 November 2018
Inhibition of protein-protein interactions: The discovery of druglike β-catenin inhibitors by combining virtual and biophysical screening
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Selective targeting to the hyperactive beta-catenin/T-cell factor pathway in colon cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304994
retrieved
28 November 2018
Eating bone or adding it: the Wnt pathway decides
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25172549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.PHARMTHERA.2014.08.005
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
961469
OpenCitations bibliographic resource ID
961469
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
961469
PMCID
4304994
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
961469
PubMed ID
25172549
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
961469
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