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Hedgehog signaling inhibitors as anti-cancer agents in osteosarcoma
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Hedgehog signaling inhibitors as anti-cancer agents in osteosarcoma
(English)
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PubMed
author name string
Ram Kumar
series ordinal
1
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Crossref
Bruno Fuchs
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
13 May 2015
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stated in
PubMed
published in
Cancers
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stated in
Crossref
volume
7
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PubMed
issue
2
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stated in
PubMed
page(s)
784-94
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stated in
PubMed
copyright license
Creative Commons Attribution 4.0 International
start time
13 May 2015
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April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway
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Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
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Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation
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Hedgehog: functions and mechanisms
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ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.
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GLI2 is a novel therapeutic target for metastasis of osteosarcoma
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Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist
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Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells
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Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth
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Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma
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Vismodegib and the hedgehog pathway: a new treatment for basal cell carcinoma
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28 September 2017
Targeting hedgehog-GLI-2 pathway in osteosarcoma.
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28 September 2017
Prevailing importance of the hedgehog signaling pathway and the potential for treatment advancement in sarcoma.
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The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma.
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28 September 2017
Molecular pathways: the hedgehog signaling pathway in cancer
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28 September 2017
Effect of the Hedgehog-inhibitor cyclopamine on mice with osteosarcoma pulmonary metastases
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Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
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Synergistic effects of arsenic trioxide and radiation in osteosarcoma cells through the induction of both autophagy and apoptosis
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28 September 2017
Arsenic trioxide inhibits osteosarcoma cell invasiveness via MAPK signaling pathway
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28 September 2017
Smoothened as a new therapeutic target for human osteosarcoma
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Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
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28 September 2017
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28 September 2017
The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells
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28 September 2017
Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.
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28 September 2017
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31 May 2018
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31 May 2018
Role of GLI2 in the growth of human osteosarcoma.
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21 January 2018
GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome
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21 January 2018
Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila
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Crossref
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21 January 2018
Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression.
1 reference
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Crossref
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21 January 2018
High grade osteosarcoma of the extremities with lung metastases at presentation: treatment with neoadjuvant chemotherapy and simultaneous resection of primary and metastatic lesions
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21 January 2018
Regulatory network of differentially expressed genes in metastatic osteosarcoma
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28 November 2018
Using targeted magnetic arsenic trioxide nanoparticles for osteosarcoma treatment
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PubMed
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based on heuristic
inferred from PubMed ID database lookup
Targeting the Hedgehog pathway in cancer
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25985215
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3390/CANCERS7020784
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3275375
OpenCitations bibliographic resource ID
3275375
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3275375
PMC publication ID
4491684
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3275375
PubMed publication ID
25985215
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3275375
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